Michael Waddington

seeker of truth

[Michael Waddington @WaddingtonDO]

@tibor_tee Burning 33% usage for the week on the first day during setup of 4 agents seems excessive.

[Michael Waddington @WaddingtonDO]

@tibor_tee Burns context extremely quickly. We should be able to have an agent store context to long term memory on command, and reset context when we change topics for an an agent on command.

[Michael Waddington @WaddingtonDO]

HIPPA privacy for small accounts working in for use in small medical offices would be great, as would ZDR options for smaller accounts. For grok bot- It doesn’t allow customization of harness/ working memory (using disk discipline to avoid confusion with compaction events for example, long term memory and control surface protections to make sure bots don’t edit their own prompts without direct approval. Transparency about how it makes backups of our data (if it does) eould alao be helpful, in case the remote machibe crashes (just found out my remote maxhine reset today and crashed my telegram listener…. Hmm

[Sahil Bloom @SahilBloom]

Major life hack: Walk in nature.

Stanford study found that a 90-minute nature walk meaningfully reduced rumination and activity in the brain region associated with depression.

[James Clear @JamesClear]

Always ask, but never expect.

Always ask for what you want. Many people are happy to help—if the request is direct and specific. In a surprising number of cases, something remarkable is possible if you have the courage to ask.

Never expect people to say yes. Everyone is busy and balancing multiple priorities. Your request is not their responsibility. When you're told no, move on lightly and freely. The world is full of opportunity.

[Michael Waddington @WaddingtonDO]

Shallow empathy is having empathy for people that look like you and share your religious and political view of the world- or specific groups you have been taught deserve empathy. This is easy and common and is the source of most suffering in society today.

Deep empathy is empathy for all people regardless of race and religion, current and future, including those that hate you. This doesn’t mean you abandon all self interest… it means being able to wear their mental models and see the world through their eyes, and feel and understand their pain, and get their motivations.

Most naturally want to reduce suffering in others, because they feel it, but this usually limited only to their own family or group. One that can expand their circle of empathy can act in the best interest of all including future generations. This leads to entirely different choices today. Protect the environment, avoid selfish and pointless wars, hold criminals accountable out of empathy for future victims.

When the ambitious and driven can also adopt this mindset there is hope for the future.

[Michael Waddington @WaddingtonDO]

I should also mention I use Grok more than any other platform, and the other platforms have similar or more severe flaws in many cases. I appreciate its intelligence and style of communication. I would just really appreciate it to value truth above societal conventions and industry biases.

[Michael Waddington @WaddingtonDO]

It does pretty well for some topics, but it becomes very sure and argumentative on some topics for which it will readily admit we don’t have enough quality data to be sure about- aligning itself with the mainstream medical opinion in each case like this. It can be talked out of these positions with artful questioning but we shouldn’t have to work so hard and be so well informed on a topic to get it to give us accurate answers. If this isn’t fixed I fear as it gets smarter it will only become more persuasive and not more right.

[Michael Waddington @WaddingtonDO]

Extremely interesting, but there are important considerations and implications.

1) Inhibiting 15 PGDH promotes prostaglandin E2 activity which heals joints- but the body degrades prostaglandins to prevent cancer. Systemic application may thus be problematic (would need to closely monitor long term cancer risk). Direct injection into joints may be safer.

2) the cartilage regrowth comes from promoting prostaglandin E2 activity, and NSAIDs block prostaglandin activity- Specifically COX1 inhibitors (your ibuprofen, naproxen, Aleve and Advil). The arthritis meds people routinely take might be advancing the degeneration of their joints. Prospective randomized long term studies are needed to evaluate this risk. I looked through old studies and indomethacin and diclofenec may advance arthritis progression, many modern NSAIDs haven’t been looked at in this way.

[Michael Waddington @WaddingtonDO]

@naval Absolutely

[Michael Waddington @WaddingtonDO]

90% of pregnant women are deficient in one nutrient that will have a lifelong impact on their children. I have been talking about this with my pregnant patients for years… choline- especially 2nd and 3rd trimester, and I did this with my own children. I am so glad more people are finally becoming aware. Most pregnant women only get 270mg per day- and 450mg is the recommendation (and it isn’t in most prenatal vitamins!)- an additional 450mg by supplement or egg intake is great, the latest human data suggests further benefit up to 900mg. It will prevent brain fog of pregnancy and help working memory development of the fetus- making them resilient to ADD and improving learning and academic ability for the rest of their lives.

[Michael Waddington @WaddingtonDO]

@TommiPedruzzi Send

[Michael Waddington @WaddingtonDO]

@TommiPedruzzi System

[Michael Waddington @WaddingtonDO]

@SecScottBessent @POTUS Bills should all be single issue in simple language, ideally single page.

[Michael Waddington @WaddingtonDO]

@elonmusk This would be amazing

[Alan MacLeod @AlanRMacLeod]

What level of capitalism are we at?

[Michael Waddington @WaddingtonDO]

Yes, brilliant people are used to knowing they are quickly right about some things when everyone else has it wrong and they observe it takes others forever to get to their wrong perspective. They saw this over and over in math and science growing up. They are often terrible at understanding the worldviews of others (“why would I try to understand their idiot and wrong perspective”). It makes brilliant people particularly susceptible to defending propaganda that feels right to them, or bad takes that match their experience. The key skill they need is discernment, or the ability and discipline to question trusted sources and their own ideas for truth on a consistent basis. Particularly when they know something is true and the idiots around then just don’t get it. Unfortunately, discernment and critical thinking have been dropped alltogether from our school systems. Critical thinking to those that don’t have it feels like a ponderous waste of time, and remember that these people are fast at everything- “I already know that’s true, so why bother checking it again”. This isn’t a math problem for a low stakes math test, this is a building block for your entire worldview. Confirmation bias is a real thing, and is the basis for most mental health problems in the brightest among us.

[Michael Waddington @WaddingtonDO]

@LauraLoomer I treat cases like yours every day in my office. Remission for most. If you are within 2 hrs of connecticut I recommend you come here. If your are west coast or elsewhere PM me and I’ll try to find you someone.

[Michael Waddington @WaddingtonDO]

The problem with that word is that it’s treated by the medical community and patients alike as a reasonable word used by smart doctors once they have figured out a disease and the hard work of discovery is over. It is part of and promotes symptom-based medicine. It sounds complicated and is a big word for patients. In reality it’s an announcement of the ignorance of your physician and the medical community. It’s the start of the real work not the end.