Amazing job by a whole gang of previous AG Bar-Even members @WeTheBarEvenLab who converted E. coli into glyoxylate growth biosensors for enzyme engineering!
Harnessing the high product titers from fermentations for aerobic productions? Metabolic rewiring makes that possible! Read below to get to know my NNmini strain allowing the selective use of respiratory modules to re-balance unbalanced fermentations!
https://t.co/GheBBjW5Xh
Happy to share our curated medium-scale E coli metabolic model out. We believe it has many application potentials, a few demonstrations shown in our preprint https://t.co/jaxUYJsUwv check it out. Great job by Marco! #Synbio#metabolism@WeTheBarEvenLab
How can lab automation, machine learning, and high-throughput screening methods be combined to speed up the enzyme engineering process? We address this question in a new article in @NatureComms, out today: https://t.co/6QnCcqKrcx
This nice work is the result of a team effort involving experts of different aspects of the whole workflow: @LennartSchada, Stephan Noach, @PabloINik and @SteffenNLindner. We believe that this can be a useful read to synbio, enzymologists and automation experts! (n/n)
We propose to combine machine learning with automated workflows and efficient selection processes in engineered bacteria to address challenges in enzyme engineering. By following this integrated approach, we aim to engineer enzymes faster and more reliably than before.
Obtaining efficient #catalysts is one of the core challenges of #bioengineering. However, combination of existing #SynBio, #computation & #automation techs can boost the way we generate these catalysts.
Check this 🧵 to learn more! (1/n)
https://t.co/s6WOi7GO3o
Very happy I was awarded this week the ' Kluyver Award' by the board Royal Dutch Microbiology Association (@KNVM_online ) for my contribution (or better our!) to microbiology, sustainable biotech, teaching and mentoring activities. Thankful to many advisors, colleagues, students
Finally out the work led by @VRBysani and @FabianMachens about the engineering and evolution of the rGP to support formate-to-pyruvate conversion in S. cerevisiae!
Check it at the link: https://t.co/plC1OnzJXA
🚨#preprint alert! Functional reductive glycine pathway in #yeast!
Have a look at our work where @VRBysani, Ayesha, Arren & @FabianMachens successfully demonstrated formate-to-pyruvate conversion while assimilating CO2 in Saccharomyces cerevisiae!
🧬🦠♻️
https://t.co/ojvm75Dt9Z
I am happy to share our publication demonstrating the functional Reductive Glycine Pathway (RGP) in S. cerevisiae, presenting evidence for nearly complete glycine and serine flux and partial pyruvate flux from formate coupled with CO2 co-assimilation is recently published.
Very cool to see this work out! Another promising new to nature/not yet discovered in nature C1 fixation pathway from the @WeTheBarEvenLab led by @haihe10@TongWu_C
Congratulations to @mirbachh on winning the add-on #fellowship of the Joachim Herz Stiftung! Helena plans to use the fellowship to gain additional computational expertise which would help to systematically find bottlenecks in engineered synthetic #CO2 fixation by E. coli.
🚨New paper! In our article, together with @PabloINik, Lars Nielsen and @BioSteDonati, we discuss current state of investigation of #natural and #synthetic C1-trophic bugs, proposing that these approaches can synergistically help each other's👇🧵[1/n]
https://t.co/mJQjIfavqx
📢The C1 Metabolism group @DTUBiosustain is recruiting! We are looking for a Postdoc (https://t.co/gR0fkC4TwE) and a Research Assistant (https://t.co/D5YsGrBsvO) to join us in our mission to understand and engineer microbes that grow on C1 substrates. Please share!
3 years ago we lost an amazing person and great scientist, but his legacy still lives on in the community he left behind—@WeTheBarEvenLab organized an elegiac yet cheerful homage to Arren as his group moves onto new endeavors. Honored to be part of this extended family🌱