Glad to see my main PhD project finally out @NatureMicrobiol https://t.co/GPTpkClhBI We show for the first time that a synthetic and engineered pathway can indeed exceed nature at one-carbon fixation.
Today I’m joining 30+ colleagues in taking an unusual step: calling for a halt to a line of research I was excited about, the long-term effort to build “mirror life”.
We’re sharing our findings in a @ScienceMagazine paper:
https://t.co/B4eXp46K84
1/6
Lets talk about #acetyl-CoA! As central molecule in C1 metabolism, the efficiency of its assimilation determines yields. Read below about our Lcm as novel activity in the shortest O2 tolerant route to make pyruvate from acetyl-CoA while fixing #CO2!
https://t.co/E3UoZNdKwy
New paper from the group developing a cutting edge genome editing tool for Cupriavidus necator! With @enricoorsi, @copa_bio, @dellavallesimo leading the work and including @NicoC_MicSynBio@PabloINik https://t.co/l0zR8eEdgX
Chek below form more info!
Great to see this work out, 7 (!) years ago we started trying to make an efficient CRISR genome editing tool for my favorite C1-utilizer C. necator . That was a challenge, but driven by @enricoorsi @dellavallesimo and @copa_bio the puzzled was cracked! SIBR(2.0)-Cas! Check it!
Vandaag zouden duizenden studenten en medewerkers in Utrecht protesteren tegen bezuinigingen op onderwijs en onderzoek. Minder geld betekent minder kansen, minder onderzoek en minder oplossingen. We zeggen: Kabinet, DOE HET NIET! 🟥
🟥 Kabinet, Doe Het Niet! ‼️
🟥 Vandaag zouden we met duizenden demonstreren tegen de desastreuze bezuinigingen 🧑🎓 , meer dan 1 miljard ‼️ Ook zonder die demonstratie laten we ons horen:
🟥 Bezuinigingen op (al het!) onderwijs én onderzoek zal Nederland tot stilstand brengen.
'#Onderzoek redt levens, daar mag niet op bezuinigd worden.' - René Bernards, biomedisch geneticus
Kabinet, stop met onverantwoorde #bezuinigingen op #wetenschap. Bezuinigen op wetenschap is bezuinigen op de toekomst van Nederland.
@flamholz@enricoorsi@WeTheBarEvenLab@erblabs@WoolstonLabNEU@LabNikel We bought one recently and will be installed soon, and bought a similar one years ago (during my PhD) which also has served well for 8 years or so, but no experience yet with this model and gas connection, but with the Neo2 (more extensive version from same brand) that works well
Our newest 'hot' preprint is out : making the thermophilic platform P. thermo bacterium use methanol, a promising recipe for future sustainable bioproduction with renewable methanol. Great work led by Miguel Paredes-Barrada @MIB_WUR! https://t.co/WsTceqBNIH