Farokhzad Family Distinguished Chair (Endowed Chair) @BrighamWomens | Associate Professor @Harvardmed | Member of Academia Europaea (MAE) | AIMBE Fellow
Thanks @NatureMedicine for this interview, and I am glad that the Drug Delivery Technologies developed in my lab can be highlighted. It is also my great honor to be alongside world's top scientists - Profs. Bob Langer, @SMitragotri, @ryanfdonnelly, etc.
https://t.co/kKMHociFmk
Sprayable Lactococcus lactis-Nanocatalyst Gel for Postsurgical Immunomodulation in Preclinical Oral Squamous Cell Carcinoma | Journal of the American Chemical Society https://t.co/MrGSgxJ5Ee
Thrilled to share our latest @natrevbioeng paper with Profs. Bob Langer @MIT, Gaurav Gaiha @ragoninstitute, et al. In this Review, we evaluate clinical trials of HIV mRNA medicine and discuss persistent challenges in developing mRNA-based interventions against HIV. @harvardmed
We are delighted to announce that our article has been selected for the front cover feature in the 2026 First Issue of American Scientist!👉
"Messenger RNA Can Do More for Medicine" https://t.co/QCNtpNCTqO
@XiangangHuang@MGBResearchNews@harvardmed
This integrative approach represents a notable advance in LNP characterization, offering a more mechanistic understanding of how structural and biophysical attributes influence functional performance. - Another fantastic work by @MJMitchell_Lab and his team! @NatureBiotech
New in @NatureNano: Systemic delivery of IL-10-mRNA NPs triggers strong immune surveillance in diverse tumor models. This #mRNA NP strategy may offer promise for overcoming recombinant IL-10's challenges in immunosuppressive tumors.
https://t.co/n0e02L6qBS
Our new paper is published as a Cover Story -"Eating the Message" in @ScienceTM. This paper demonstrates that oral mRNA delivery to the intestines is feasible using our RNACap design. Congrats to our Rising Star @XiangangHuang and the team!
Engineered “RNACaps” provide oral delivery of liquid #mRNA therapeutics to the intestines in small and large animals for the treatment of #colitis and could support the clinical translation of oral mRNA therapies. @WeiTaoLab@BrighamAnes@XiangangHuang https://t.co/SjKazC1QdZ
RNACap can orally deliver liquid mRNA therapeutics to the intestines in response to intestinal pH, the resulting pressure release, and contractions
https://t.co/bQdyg0VYDQ @ScienceTM
The new issue of #ScienceTranslationalMedicine has arrived!
Engineered capsules can deliver liquid mRNA therapeutics to treat intestinal disease in animals, the complement cascade offers a target in acute chest syndrome in sickle cell disease, and more. https://t.co/NELkknKnH9
By loading different types of mRNAs, new oral mRNA vaccines for infectious diseases and oral mRNA medicines for cancers are possible. This technology could also benefit the oral delivery of other types of biologics (e.g., nucleic acids and proteins) to tackle different diseases.
Happy to share our most recent article on using RNA therapeutics to promote healthy
aging @NatureAging. Congrats to Shuying and Qian from my team. Link here: https://t.co/HywyjJyD8a