@RenoHemonc@BertrandBio My understanding is that the concern here with CAR-Ts is around insertional mutagenesis that could occur during the genetic engineering process with lentiviral vectors, which wouldn’t be a concern with bispecs.
@VergudoForU@FDACBER This is a risk worth taking for a cancer treatment, but now companies are studying these CAR-T therapies in chronic immune conditions where the risk might not be worth taking.
@VergudoForU@FDACBER CAR-Ts are white blood cells that get their DNA modified to hunt cancer, but the way the DNA gets modified is pretty random so there’s a very small chance the new cancer hunting DNA screws up existing cancer preventing DNA in those cells and they actually become cancer.
@DylanMSmith3@bendreyfuss@AlexMLeo Yeah, they added specific limits because some guy in a camero successfully argued to the Montana Supreme Court that going 85 mph was a “reasonable and proper” speed and that he should’ve have been ticketed.
Love that creating a Threads account automatically sends out follow request notifications to hundreds of people you haven’t spoken to in years. Absolutely unforgivable.
@JMannhart@nisten Yeah, I finally got around to watching the whole 40 minute interview last night, and while your clip shows the juiciest parts, I don’t think you misrepresented his thoughts at all.