Wilson Lab

We are a molecular virology lab led by @samjwilsonphd.

ISGs and viruses (SARS-CoV-2, HIV-1, IAVs).

[Wilson Lab @WilsonLabCITIID]

New @wilsonlabcvr paper. Our work, led by @virologist_atu, showing that the prenylated variant of OAS1 can sense SARS-CoV-2 and protect against severe #COVID19 is out in Science:

https://t.co/pMcnLroGbm

#CVRCovidResponse
🧵 (with some new bits)

[Ellen Foxman @EllenFoxman]

Our new paper @JExpMed - Nasal viruses & bacteria are very common in children (90% of symptomatic and ~50% of asymptomatic <5yrs!), and activate nasal defenses, which may have protected from #Covid_19 @YaleMed @Yale_LabMed @YaleIBIO @YalePediatrics
https://t.co/cxRMJctiEt

[Kenneth Baillie @kennethbaillie]

I always say jobs in my lab are great opportunities but this one really is. The last incumbent published 3 1st-author @Nature papers, found a treatment for Covid, and now has a senior job in pharma.

Quantitative geneticists - please consider joining us!

https://t.co/W1nRZt7zTk.

[Suzannah Rihn @Lab_Rihn_th]

🔔'Tis the season...to apply for a new job?! My group @MedCambridge is recruiting for 2 posts:

Postdoc: https://t.co/65QjHYDpXk
Research assistant: https://t.co/1vSF3py32A

Both roles will seek to improve our understanding of coronavirus cross-species transmission. #preparedness

[Robert Gifford @Paleovirologist]

A lovely piece of work that places interferon-mediated antiviral immunity to betacoronaviruses into evolutionary & ecological context.

[Ryan Hisner @LongDesertTrain]

Really interesting thread and paper about an anti-coronavirus gene in humans that bats lost millions of years ago, which could help explain why bats are such prodigious reservoirs of coronaviruses, posing a constant threat of spillover into humans.

[Spyros Lytras @SpyrosLytras]

🚨New paper alert! and it's one I'm really excited for! Resurrection of OAS1 from the ancestor of modern horseshoe bats blocks SARS-CoV-2 replication now out in @PLOSBiology

Here's a 🧵on how we reconstructed an ancient 🦇anti-CoV protein

https://t.co/N96BooeewT

[Wilson Lab @WilsonLabCITIID]

Thanks to all the authors and the MRC/UKRI for funding this work.

[Wilson Lab @WilsonLabCITIID]

New WilsonLabCITIID publication led by @SpyrosLytras where we reconstructed an ancient OAS1 from the ancestor of modern horseshoe bats and demonstrate it possessed anti-SARS-CoV-2 activity.

https://t.co/kPjlrAOO0m

[Wilson Lab @WilsonLabCITIID]

This study builds on our previous work demonstrating human prenylated OAS1 (p46) inhibits SARS-CoV-2 whereas the nonprenylated (p42) form does not.

https://t.co/pMcnLroGbm

The nonprenylated human OAS1 p42 is not functionally analogous to nonprenylated horseshoe bat OAS1.

[Suzannah Rihn @Lab_Rihn_th]

One thing the pandemic forever changed for me was my perspective on sharing biomaterials (tools and reagents) from publications. I’ve written about this, with co-author Alexander Harms (@AHarms485), in our new PLOS Biology perspective:

[FL Cosset's lab @EvirTeam]

Join our EVIR team in the fight against the Crimean-Congo hemorrhagic fever! We're looking for a Research Assistant to work on #CCHFV. Contact us for more info or to apply!

[Wilson Lab @WilsonLabCITIID]

Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses.

https://t.co/Danx8wIKn6

Deadline Oct 1st 2023

[Wilson Lab @WilsonLabCITIID]

More positions to follow soon from @Lab_Rihn_th

[Wilson Lab @WilsonLabCITIID]

Please RT. Are you interested in how viruses emerge in humans? We're looking for a postdoctoral investigator to join us and lead exciting projects investigating innate immune barriers to the emergence and pathogenesis of viruses.

https://t.co/Danx8wIKn6

Deadline Oct 1st 2023

[Wilson Lab @WilsonLabCITIID]

We'll be invested in supporting your career and development. If you'd like more info, contact @samjwilsonphd, or read our recent papers:

https://t.co/7oC3kGR05s
https://t.co/pMcnLroGbm

[Fodor Laboratory @fodorlab]

📢 Exciting job opportunity! 📢

A postdoc position is available in our lab at @Dunn_School @UniofOxford to study influenza virus transcription, genome replication, nuclear export and assembly.

More info: https://t.co/SCVM4BJeMb

[Spyros Lytras @SpyrosLytras]

✨New title unlocked!!✨ Finally a Dr! Big thanks to @katrina_lythgoe and @rbiek for a great viva and ofc to my wonderful supervisors for the past four years @blJOg @SamJWilsonPhD @robertson_lab!! 😁😁🎉🎉

[Richard Jenner @RegGenomics]

Join us! A postdoc position between my lab and @QuezadaLab has become available at @uclcancer in London. Please help us characterise the molecular mechanisms through which anti-tumour immune responses are controlled.

To apply
https://t.co/NiFHxhlg49

Deadline 14 Sept

Please RT!

[Marc Johnson @SolidEvidence]

This talk is open to the public if anyone is interested.

Thursday at 5PM EST.