Researchers used a new single-cell profiling technique, PheP-Seq, to study HIV reservoir cells. Results suggest that only small subsets of infected cells survive long-term ART. https://t.co/8KiCpaJaRB @YuLabAtRagon@Nature
In this new study, our team reports the longitudinal selection for intact proviruses integrated into heterochromatin regions after two decades of ART.
https://t.co/VBVsRmvsn9
Researchers analyzed HIV reservoirs and found that long-term antiretroviral therapy causes the immune system to select for latent reservoirs that cannot be easily reactivated. Press release: https://t.co/HZQb6dXKJc @cellhostmicrobe@YuLabAtRagon
We have awarded our second grant of the year to to Mathias D. Lichterfeld, MD, PhD. and Catherine Koofhethile, Ph.D. https://t.co/kYnGOCYsu0 @ragoninstitute#HIV#AIDS
Last week, the Ragon Institute had the pleasure of welcoming Dr. Sikhulile Moyo. Dr. Moyo is one of the leading experts in immunology and HIV research in Botswana. He is known for his identification of the Covid-19 Omicron variant. Learn more -https://t.co/rJHtwkmIQj
#immunology
Congrats to Kyra Seiger for her presentation at #CROI2022! For a unique cohort of people living with #HIV who have been on #antiretroviraltherapy since its advent, intact HIV-1 proviruses accumulate in more transcriptionally silent regions.
Third person CURED of HIV!
HIV-infected individual treated with CCR5d32/d32 cord/haplo stem cell transplantation has 14 months ART free, AML free, no evidence of HIV reservoir, no evidence of immune responses to HIV. CURED!
By Yvonne Bryson/IMPAACT P1107/Deborah Persaud
#CROI2022
Last month #amfAR held a think tank on how to control #HIV w/out ARVs where scientists in attendance hope to collab w/amfAR in a study to enroll people who have been on ARVs for decades to examine their HIV integration patterns on the path to #HIVcure. https://t.co/IKvo8Q3d8S
A major day for @ragoninstitute! The Cambridge Planning Board unanimously approved plans for our new building. Construction of Ragon 2.0 begins immediately on last land in Kendall Square. The CPB called it "a landmark", "extraordinary". We + @MGH_RI @MIT@Harvard agree!
So proud of Xu Yu, Assoc Prof @ragoninstitute@mgh@Harvard who was just awarded an NIH R37 Merit Award!! Her research on elite controllers and #hiv is super exciting- see this about her recent paper: HIV cure is possible? https://t.co/de7X9XiLxC