Yossi Quint

Human & rescue dog dad (2x). Founder @ Ark Biotech

[Yossi Quint @YQuint]

On one program: yield 43% above a top pharma's historical best, in three weeks.

When manufacturing keeps pace with discovery, rare diseases, cell and gene therapies, and N=1 medicines stop being economically marginal.

Essay: https://t.co/Dq0HvKq6rx

[Yossi Quint @YQuint]

We can discover drugs at the speed of silicon.

We still make them at the speed of cells.

AI is about to flood the pipeline with new drugs. The next bottleneck isn't finding them. It's making them. 🧵

[OpenAI @OpenAI]

We’ve acquired Orchestra Bio, a platform that helps biopharma teams coordinate the complex process of drug development.

Together, we’ll build on Rosalind, our AI models and tools for life sciences research, to streamline those operations and help new treatments reach patients sooner.

Welcome @ashokaraj_ and team!

https://t.co/vi51OhznQn

[Yossi Quint @YQuint]

Drug manufacturing is the industry that never built a simulator. Too little data for AI alone, too little settled science for physics alone.

So we built a world model where the neural net is a term inside the physics, and agents that steer every run live.

[Kevin Wimer @kevinace]

https://t.co/YGKEnA2Hvp

[Yossi Quint @YQuint]

@BSchech Building the dream team!

[Yossi Quint @YQuint]

@patrick_oshag New @FoundersPodcast dropping? 🤞

[TBPN @tbpn]

"I think what tech people misunderstand is just the size of the TAM in pharma."

@zebulgar says capital will rotate into pharma after AGI:

"Anthropic is at what, a $60B run rate? Keytruda, the drug that Merck did in 2019, that one drug's topline is $25B in revenue. Just that one drug."

"By the way, once there's AGI, what do you think everybody's going to be focused on afterwards? Everybody's just going to want to live forever. Where do you think the capital is going to rotate into? It's going to rotate into longevity, therapeutics, and manufacturing."

[Yossi Quint @YQuint]

@patrick_oshag https://t.co/LYTfoDn1P8

[Yossi Quint @YQuint]

@patrick_oshag Seven Samurai and Setting the Table by Danny Meyer

[delian @zebulgar]

BREAKING NEWS

Ron Desantis signs a bill into law that bans the use of steam engines in the state of Florida

"Until we have decades of safety data, we cannot allow consumers to access these engines, we already have donkeys that can run our mills"

[Yossi Quint @YQuint]

Thanks for highlighting @ArkBiotech's work. We're proud to be pioneering the tech essential for the biorevolution, from cultivated meat to life-saving medications.

@SenFettermanPA the choice is clear: we either seize the opportunity to anchor this future right here in America (Make More Sh*T in America 🇺🇸), or we risk watching more jobs slip through our fingers to overseas competitors. Senator - would love to show you around Ark and discuss how we can strengthen US supply chains, bolster our economy, and improve national security.

[U.S. Senator John Fetterman @SenFettermanPA]

btw, this is the thing that makes lab meat

[Matt Fay 🌱 @mattefay]

We just opened up an incredible role focused on commercializing our technical platform — bioprocess modeling, simulation, optimization, and real-time control. Are you product-focused, with a deep knowledge of biotech and B2B software?

This job's for you!

https://t.co/I6gOkgaINB

[Yossi Quint @YQuint]

@SexyLikeMeiosis (1) dynamic nature of biological systems (linearities, hard to model) (2) accurate understanding of differences in geometry between bioreactors. This is a solvable problem and @ArkBiotech has built an robust digital twin for (1) and uses CFD for (2).

[Yossi Quint @YQuint]

@tferriss @FoundersPodcast 311: James Cameron
266: Henry Ford
238: Jay Z

[Yossi Quint @YQuint]

@eatscifi Congratulations!!!

[Eshan | Better Bioeconomy ✉ @biotecheshan]

🥩 @YQuint on cultivated meat capacity:

“If Samsung Biologics [world's largest cell culture facility] were to be running every single minute of every single day for an entire year, they would produce less cultivated meat than the average Tyson facility produces in one day...

[Yossi Quint @YQuint]

It’s not about incremental change. We’re talking about a revolution, and that means reimagining what infrastructure looks like... At Ark, we are offering the path for industry to succeed.

https://t.co/MORc217LhN

[Yossi Quint @YQuint]

@sethbannon 💯 At @ArkBiotech we’re making biomanufactured goods available to the masses

[Noah Kaufman @noahqk]

Nice figure from the White House on actual EV sales versus AEO projections (or, as they call them, AEO forecasts, because they are forecasts)
https://t.co/HNGKvCpPAl

[Yossi Quint @YQuint]

Technological progress is non-linear.

Monumental innovations don’t happen overnight. Mass production takes time to get started.

Turning moonshots into meals is not easy, and yet, company after company have developed mouth-watering products.

And the reality is that cultivated meat has made tremendous progress. Ten years ago, a Dutch professor unveiled the first cultivated burger. Since then, we've seen costs plummet 99.99%.

Of course, companies are going to try things that fail. Every great achievement comes after repeated failures.

Take the lubricant spray WD-40. The full name is Water Displacement 40th formula. The first thirty-nine version of the formula failed. But, the chemist learned from each one of those failures and nailed it on the fortieth try.

The cultivated meat industry has solved some of the biggest, hardest, show-stopper problems.

And, we still need to constantly refine and improve. Better is always possible.

Innovation is perpetual.

https://t.co/L14V6NBayX