Zac Germon

Project Manager @ CSRG - University of Newcastle | HMRI #DIPG #DunLab

[Hawkins Lab @CHawkinsLab]

proteomic landscape of diffuse midline glioma highlights the therapeutic potential of non-histone protein methyltransferases https://t.co/Xy1gNY5j69

[Zac Germon @ZacGermon]

@MattDun17 @charles_debock @NatureComms @KidsCancerInst I have! Amazing data, congrats to all involved.

[Zac Germon @ZacGermon]

@Ritchlynn_A @TheASMR1 Thanks Ritch!

[Zac Germon @ZacGermon]

Had a great day at @TheASMR1 Hunter meeting. Grateful to have been awarded Best ECR/MCR talk on the day!

[Zac Germon @ZacGermon]

@MattDun17 @Mika_Persson97 @RUNDIPG Congratulations Mika!!

[Zac Germon @ZacGermon]

Thanks Heather, looking forward to it!

[Heather Lee @Dr_Heather_Lee]

On July 18, I'll be hosting @XuDongZhang15 and @ZacGermon at an online seminar for @AEpiA. I'm looking forward to showcasing the work of two great colleagues from @UON_research and @HMRIAustralia . Tune in for some fabulous science and discussion!

[Zac Germon @ZacGermon]

@DavidSkerrettB @nhmrc Great news, congratulations David!

[Zac Germon @ZacGermon]

Thanks @CancerAustralia & @KidsCancerProj! Excited to be given the opportunity to continue this project investigating much needed novel treatment strategies for Paediatric cancers #AML #DMG #DIPG

[Matt Dun, PhD @MattDun17]

Delighted #DunLab 's childhood cancer project was funded by @CancerAustralia & @KidsCancerProj
Free-radicals (#ROS) promote cancer signaling in RTK mutant- #AML & #DMG #DIPG
Here we will develop new targeted treatments
Congrats @ZacGermon @duchatel_ryan @Jonatha16752881 DE & ID

[Matt Dun, PhD @MattDun17]

Wonderful to see the glossy version & cover of #DunLab’s latest paper discovering the genetic dependency & targeting of PI3K in #DIPG #DMG
Huge thanks to the funders & parents who donated their child’s tissues to help us in this & all our important studies https://t.co/JTv8nXdrDl

[Zac Germon @ZacGermon]

@williamreay96 Congratulations Will! All the best in Tassy!

[Zac Germon @ZacGermon]

Congratulations @MattDun17! So well deserved. Your dedication and determination inspire us each day in the fight against kids cancer!

[Matt Dun, PhD @MattDun17]

So thankful to receive this prestigious award on behalf of our incredible #DunLab team
May I thank all our #CSRG team & recognise the inspirational scientists that did all the work particularly @evierjackson @duchatel_ryan @AliciaD0uglas @DilanaStaudt @ZacGermon #DIPG 💪 @RUNDIPG

[Matt Dun, PhD @MattDun17]

What a team #DunLab 2023-2024

[Zac Germon @ZacGermon]

Congrats, Sam and team! A super interesting review. Thank you for the opportunity to contribute.

[Heather Lee @Dr_Heather_Lee]

Our new review on #hypoxia and #DNAmethylation in #AML is online today. We explored complex and bi-directional interactions between hypoxia signalling and regulation of DNA methylation as well as implications for AML therapy.
https://t.co/JsWcL8h2cw

[Zac Germon @ZacGermon]

@DavidSkerrettB @Science_Academy @epi_tep @HelmholtzMunich Congrats David!

[Zac Germon @ZacGermon]

@Bryce_Thomas23 @DilanaStaudt @MattDun17 @VitanzaNick @michelle_monje Congrats Bryce and team, on a great paper and an awesome image!

[Zac Germon @ZacGermon]

@MattDun17 @PrecisionMedUON @UON_research Thanks Matt, and thank you for all the support and opportunities you have given me along the way. To be continued!

[Zac Germon @ZacGermon]

Congrats Evie and team! Great summary of this paper below.

[Evie Jackson @evierjackson]

Incredibly proud to share the latest work from #DunLab, published in #CancerResearch! We highlight the combination of ONC201 and paxalisib for the treatment of DMG, the preclinical data informing PNOC022. Follow this tweetorial for a summary: (1/10)
https://t.co/rG6RK1t08r

[Science Signaling @scisignal]

A new study shows that inhibiting the oxidase NOX2 suppresses a common subtype of #AcuteMyeloidLeukemia (AML) in mice by blocking ROS in cancer cells—hinting that targeting NOX2 may potentiate precision therapies for AML. @ZacGermon @MattDun17 https://t.co/qEbbWBuAn0

[Matt Dun, PhD @MattDun17]

Probably my favourite part of adding to the literature, students/stuff pinning their first author papers to our walls of honour!
#DunLab #CSRG

[Zac Germon @ZacGermon]

Excited to see this paper published today in @scisignal. This work formed a large part of my PhD and is summarised below:

[Matt Dun, PhD @MattDun17]

#DunLab paper alert:
Patients diagnosed with the most common driver mutation in acute myeloid leukemia (AML) – FLT3, are associated with poor-outcomes.
FLT3+ AML sees the overproduction of reactive oxygen species (ROS), a second messenger signaling (T1)
https://t.co/ut8hnZogVQ