Laura Spinelli

Postdoc in Miller Lab, University of Dundee-
Former postdoc in @LabDac, University of Dundee

[Laura Spinelli @_LSpinelli]

Delighted to share our latest work in @FrontImmunol using #RNAseq and #proteomics to explore the different contributions of #PI3K p110d to #Tcell antigen receptor control of naive versus effector CD8+ T cell fate. @labdac @jmarchingo @UoDCellSigImm
https://t.co/SYeibywFR2

[Laura Spinelli @_LSpinelli]

@G__Napolitano @Nature Congratulations Gennaro and team!

[Ganley Lab @LabGanley]

SAVE THE DATE!!

[Alejandro Brenes @AJ_Brenes]

In-depth microglia #proteomes showing the differences of in-vitro and ex-vivo!

Importantly a xenografting them back into a mouse brain reverts them back to their pre in-vitro state, showing the importance of the microenvironment to reprogram the cells. Well done Amy!

[Linda Sinclair @LindaVSinclair]

Fly little bird… fly!!!

[Laura Spinelli @_LSpinelli]

@DundeeCulture Luigi's Pizzeria

[Royal Society of Edinburgh @RoyalSocEd]

🎖️ Professor Doreen Cantrell is the first woman to receive an RSE SIR JAMES BLACK MEDAL. Working at @UoDLifeSciences at @dundeeuni she is an international leader on cell signalling; the mechanisms that control the function of key immune cells.👏

https://t.co/oWiTkn1Ryl

[bioRxiv Immunology @biorxiv_immuno]

Quantitative proteomics reveals tissue-specific, infection-induced and species-specific neutrophil protein signatures https://t.co/RZX5bbnXwa #biorxiv_immuno

[bioRxiv Immunology @biorxiv_immuno]

Rewiring of the TCR signalosome in natural intestinal Intraepithelial T lymphocytes drives non-deletional tolerance https://t.co/mtRcsLUIMj #biorxiv_immuno

[Irene Cantone @CantoneIrene]

We are looking for a #postdoc to join our group (up to 3yrs):
- Develop a project on the #epigenetics of #sex_bias in #autoimmunity using our favorite model system: #XChromosomeInactivation
- Use genome-engineering, flow-cytometry, single-cell transcriptomics and more
Please RT

[Immunological Proteome Resource @ImmPRes_]

📢📢 New dataset alert. The "PI3Kδ regulated TCR retriggered CTL proteomes" is now live on ImmPRes.

Want to know what inhibition of PI3Kδ does to CTL proteomes when they are TCR activated a second time? You know where to look

#tcells #PI3Kδ #proteomics

[Laura Spinelli @_LSpinelli]

@LabDac @UKBspr @EuPAProteomics Congratulations Alejandro 🎊

[Cantrell Lab @LabDac]

📣A single-cell assay for SLC1A5 uptake capacity : glutamine uptake on a flow cytometer!!! See tweetorial for details, see Cell Reports for paper

[Linda Sinclair @LindaVSinclair]

** UPDATE** now online @CellReports @CellPressNews QUAS-R: An SLC1A5-mediated glutamine uptake assay with single-cell res... https://t.co/OLR0gpWdtE

[Buzz Baum @BaumBuzz]

As scientists we know the Climate Emergency is upon us. We need to act. So, how many meetings should we fly to per year? If it’s <12 hours by train should we refuse to fly? Should we let postdocs go (for their careers) in our stead? Are we boycotting les Treilles and SLB support?

[Laura Spinelli @_LSpinelli]

@HenryMcSorley Had issues yesterday..

[Dr. Liz Miller @LizMillerCU]

PhD opening in my lab at the University of Dundee open to UK-based students. Details in link below - reach out if you have any questions!

https://t.co/F88iXSAJ1X

[Sarah Ross @sarah_h_ross]

An exciting opportunity to lead the @SciImmunology editorial team⬇️

[Cantrell Lab @LabDac]

🎉Check out this new paper from former DACmember Aneela Nomura 🎉
Identification of a novel enhancer essential for Satb1 expression in TH2 cells and activated ILC2s | Life Science Alliance #Th2 #ILC2 https://t.co/gPInfKP3bV

[Linda Sinclair @LindaVSinclair]

So happy and proud to see this paper out now! Big collaborative effort - well done @KediaMehta @AndyHogan82
“The proliferation of human mucosal-associated invariant T cells requires a MYC-SLC7A5-glycolysis metabolic axis” https://t.co/ORwKlewHm7

[MRC PPU @mrcppu]

Success! First Dundee #Parkinsons patient randomized for Biogen Luminare #LRRK2 kinase inhibitor trial