Prosad Kumar Das (he/him)

Computationally versed biologist @IGIBSocial, @iiserkol alumnus | CRISPR | genomics | Ambivert | Nyctophile

[eLife - the journal @eLife]

Controlling the forces needed to move around is pretty complicated for soft-bodied organisms. Researchers have implemented a new technique for measuring these crawling forces with nanonewton precision in fruit fly larvae. https://t.co/ZMCDF9yFR8

[Richard Tennant @richardktennant]

Great to be back in the field doing some @nanopore eDNA work using our @theBentoLab! This time we’re in Jersey, part of the @ConvexSeascape, looking for the origins of blue carbon input.

[bioRxiv @biorxivpreprint]

Unravelling differential Hes1 dynamics during axis elongation of mouse embryos through single-cell tracking https://t.co/ukRq46XPn1 #bioRxiv

[bioRxiv @biorxivpreprint]

A multi-tissue de novo transcriptome assembly and relative gene expression of the vulnerable freshwater salmonid Thymallus ligericus https://t.co/6uEEMBsQ74 #bioRxiv

[Mònica Sánchez Guixé @guixe_m]

Our work on the origins of second malignancies in children is out in Cancer Discovery @IRBBarcelona @bbglab @IRSJD_info
https://t.co/OICCeoTFOC
1/16

[omri_drory @omri_drory]

Growing glowing plants!

[PLOS Biology @PLOSBiology]

#Galactose is an important sugar that can fuel glycolysis, but tracking its metabolic dynamics in vivo is challenging. @Yoo_Lab_RIKEN describe #GALDAR, a genetically encoded sensor to measure intracellular galactose dynamics in flies #PLOSBiology https://t.co/B7C7JeDYbw

[Benjamin Towbin @betowbin]

only that Fig. 6 actually ends up being Fig. 1 ...

[PLOS Biology @PLOSBiology]

Some drugs increase the #mutation rate of their target #pathogen, raising the concerns they might increase the pathogen’s rate of adaptation. This #PLOSBiology Perspective proposes a four-step process to evaluate the evolutionary safety of new treatments.

https://t.co/E7MlKtP1Ca

[Adam Cribbs @AdamCribbs]

New paper from our group: we show that PCR, not sequencing, is the main source of error in bulk and single-cell expts and we correct these experimentally using UMI homoblock design. https://t.co/vJPKcc4afs

[Manas Pratim Chakraborty @ManasPratimCha1]

Excited to share our recent findings on VEGFR1 autoinhibition. Thanks to Molecular signaling lab @SwarnenduRoy10 @SubhankarC20, soumee, Bipra, @sayargh_ @KaustavGanguly1
special thanks to @DasDiptatanu, pragya kaul,@_SazAbad
https://t.co/r4KLt7HCm6

[Stowers Institute @ScienceStowers]

The Sea Lamprey may be a monstrous-looking sea creature, but it’s also an incredible organism for studying how the #brain evolved! 🧠 #biology #evodevo

Learn more about these #UnordinaryOrganisms: https://t.co/oTmaaQ1kvS

[Robert Aboukhalil @RobAboukhalil]

Just released a BLAST tutorial on https://t.co/3DKXXBduDD!

Learn to align DNA and protein sequences on the command line:

➡️ https://t.co/0aFNDET09A

This tutorial was adapted from @shawntoneil's fantastic book.

[Uri Alon @UriAlonWeizmann]

E. coli engineered to become stem cells that differentiate! We prevent take-over by mutant stem cells that only self renew - by linking differentiation to an essential function. A new way to engineer stable microbial communities.
https://t.co/GW9XXWNYVg

[Patrick Hsu @pdhsu]

In an era of RNA delivery and therapeutics, we sought to “write” RNA molecules directly into messenger RNA to replace disease-causing exons or engineer synthetic proteins

Our new work on RESPLICE enables fully programmable and highly efficient (45-90%) transcriptome engineering

[Jason Shepherd @JasonSynaptic]

Transposons FTW...yet again! The more we discover about these "junk" elements...the more actual gold we find. Super cool findings from Patrick's lab!

[Bob Johnston @BobbyJEyeGuy]

Humans are one of the few mammals that have both red and green cones. A stochastic gene regulatory mechanism was the main model in the field. @hadyniaks in my lab changed the view, finding that retinoic acid controls their spatiotemporal patterning. https://t.co/QgU96EFBrj

[Alison Feder @AlisonFeder]

Excited to share the published version of this in @MolBioEvol!

Elena Romero developed an approach to quantify recombination from longitudinal short read sequencing, and applied it to measure differences in recomb rate in HIV pops with low and high VL.

https://t.co/7fXEHlh0Ic

[Anthony Bonato @Anthony_Bonato]

I’m in a plane reading about infinity categories to pass the time and I think I want to jump out of it.