@jrkelly@Ginkgo Looking forward to see cell line DNA transfection + luciferase/fluorescence readout. Many therapeutic protein approaches could be enabled!
We’re looking for an enthusiastic postdoc to join our team. 😊
The project focuses on protein design and cryo-EM applied to cancer research. 🔬🧪
Position funded for 3 years.
Please share 🙏
Job description and details (deadline: October 11th): https://t.co/GIvf8LmbpU
Very happy to report today bioprospecting and AI-generation of high performance gene writers @NatureBiotech@Synbio_Lab_UPF@Integra_Tx@UPFBarcelona
https://t.co/AwfMVdR7qy
READ/WRITE tech fueled DNA molecular technologies development. Extremely exciting to see how AI starts to enable to 'SPEAK' the language of life. Enabling the generation of synthetic diversity is a fundamental step for future synthetic evolution which opens new horizons in engineering biology.
We explored and experimentally tested the natural diversity of PiggyBac transposases. We then used this natural data to train protein language models. This generated protein variants with increased efficiency compared to the the current best PiggyBac transposase, HyPB.
The improved variants are compatible with therapeutic T cell editing and Cas9-guided programmable integration. We also observed domain acquisitions in parts of the HyPB phylogeny. Stay tuned for future work on improving gene writing systems.🧬❇️
1. Happy to share our latest work @biorxivpreprint on developing SONAR (Sensing Of Nucleic acids using ASOs and Reverse-transcriptases) for sensing and responding to nucleic acids in living cells.
https://t.co/2k74P3RvOk
👇🧵
I am very proud to share that our ‘epitranscriptomic fingerprinting’ manuscript is now published in @MolecularCell ! You can access the article here: https://t.co/40fB4MJF1T; for highlights see the thread below. (1/11)
We're currently looking for new members to join our lab! If you're excited about this research, feel free to reach out!
We already have two open, fully funded positions:
🔬- Postdoc: https://t.co/cKH9W9uNOG
🧪- Senior Scientist: https://t.co/ZsnAaGMrZ8
Join us at 11th Mammalian Synthetic Biology Workshop in Boston! https://t.co/zeC1DY2Pxh
Our Innovation Scientist Dimitrije Ivančić (@_dimiid) will present new PiggyBac transposases to increase the performance of #FiCAT
Chairs: @GallowayLabMIT & @johntngo@BostonU_BME#mSBW2024
#JobOffer#JobPosition
The @Synbio_Lab_UPF, located at @the_prbb, is recruiting an Immune Cell Engineering Scientist to join our team.
The project involves developing technologies for in-vivo immune cell modification for #CART therapies.
Apply now 👇🏽
https://t.co/WxvSCyev3n