Ian Boys

NIGMS K99 fellow (formerly LSRF) w/ @ElEarlyBird. Interests include viral evolution, comparative immunology, exploring the outdoors, and cooking.

[Ian Boys @_iboys]

A bit under two years ago, @ElEarlyBird & I jumped on the #AlphaFold2 bandwagon. Could ab initio modeling guide studies of host-virus interactions in poxviruses? For the deep dive, see our @CellReports article https://t.co/WmLBlhzNno. For some highlights, continue below!

[Justin Bosch @jakbosch]

I’m thrilled to share a @biorxivpreprint for my postdoc work in the @PerrimonLab🎉. Together with our collaborators, we built a tissue-specific atlas of circulating secreted proteins in Drosophila 🧬🪰🧪🗺️.
Thread below🧵
1/8
https://t.co/oRvsdpogof

[Ian Boys @_iboys]

I'd love to be in a timeline where an AI wouldn't cold-email you having "read" your recent preprint and come up with an "exciting Novel Hypothesis" to improve your work that is, shocker, largely behind a company's paywall. This isn't what we should be using ML for, dammit.

[Ian Boys @_iboys]

Does anyone have a sense for how long it takes for an unannotated eukaryotic genome to process w/ NCBI following submission? The official "at least two weeks" is pretty vague & we're closing in on a month and a half.

Also it's 2025 so I guess past experience may be irrelevant.

[Ian Boys @_iboys]

@thesteinegger Super excited to have this resource as an alternative to folding viral proteins "in-house" - thank you!

[Ian Boys @_iboys]

Have been pretty quiet here for a while, but this is something I'm supposed to excitedly share, no?

Extremely excited to begin my transition into the next phase - lots of exciting work on the evolution of immune (and anti-immune) proteins ahead! Thank you @NIGMS!

[Emily Anderson Stern @emilyreanderson]

Nearly a thousand fewer doctors applied to residency programs in Utah this year.

Researchers noticed a pattern among the states experiencing the most severe losses in applicants: They had adopted restrictive abortion policies.
https://t.co/4y8hEtbxQ3

[Ian Boys @_iboys]

@Wenchun_Fan Just cells!

Though I do have a couple of tanks of snails... 🐌

[Ian Boys @_iboys]

"gekko cells are extremely sticky" ranks pretty high on my dumb little internal list of things I find funny, right next to "for frog cells, take culture media and dilute it with a ton of water"

[Ian Boys @_iboys]

Oh also: "snail cells grow really slowly" might top said list

[Omaya Dudin🍉¦ 🦠¦🔬¦ @dudin_o]

#PreprintAlert🚨Please share.

Our latest #Ichthyosporean #EvoDevo story, led by M. Olivetta @ChandniBhickta @NChiaruttini & in co. with @burnsajohn.

**𝗧𝗵𝗶𝘀 𝗶𝘀 𝗡𝗢𝗧 𝗮𝗻 𝗮𝗻𝗶𝗺𝗮𝗹 #𝗲𝗺𝗯𝗿𝘆𝗼**

LINK ➡️https://t.co/zdiu7zlfPy

Buckle up for a LONG 🧵(sorry)

[Ian Boys @_iboys]

Follow-up: I ended up borrowing someone's computer to do this using Geneious. I try to avoid expensive software (especially subscriptions!) when community alternatives exist, but man did it make this easy.

[Ian Boys @_iboys]

Does anyone have tool recommendations for sgRNA design using an in-house (nonmodel) assembled genome as a reference for specificity? Seems like there are several options, wondering if anyone could vouch for specific ones. Thanks!

[Ian Boys @_iboys]

I'm late to the party retweeting this, but I highly, highly recommend taking a look at the Hilbert lab if you're interested in evolution and fungal pathogens. Zoë is an amazing scientist and will be a fantastic mentor for you if this is up your alley!

[Zoë Hilbert @zoehilbertspace]

Opening day of the Hilbert Lab @BiologyBC @BostonCollege --can't wait to see what awesome science we get up to in this space in the years to come! Looking for anyone with a passion for evolution, fungal pathogens, and curiosity-driven science to come join us!

[Ian Boys @_iboys]

A section of a paper in a reputable journal is dedicated to “identifying” something you published two years ago and fails to cite your work/the body of work yours itself was built upon...

[Nels Elde @ElEarlyBird]

A little late to the party. Please apply for our newly posted faculty position in Evolutionary Genetics - broadly defined- here in the Department of Human Genetics at Utah @UofUHealth. PS: the photo below was taken 15 minutes from your new lab.

https://t.co/BE20HTR7Wr

[Ian Boys @_iboys]

@jkagan1 @russellevance IRF1? Makes sense as an individual, somewhat gentle/specific driver of some inflammatory signaling/IFNs, and a quick pubmed search turns up at least one study demonstrating it as an adjuvant in another vaccine type.

[Ian Boys @_iboys]

@Aakanksha__Jain @FMKirbyNeuro @ThePasareLab Congrats Aakanksha!!

[Ian Boys @_iboys]

@ProfessorPowder The other direction was pretty cool too

[Ian Boys @_iboys]

@ClementYChow In our defense we at least stuck with ones that were shoulder/pork/ham-adjacent. There was also a duck confit one that looked tempting...