Nathan Winters

Neuroscientist. He/him; Opinions my own.

[Veronika Kondev, PhD @veronikakondev]

Curious how astrocytes in the PFC regulate the negative effects of stress?
Read our preprint on Biorxiv now:
https://t.co/UcHrGvCkkp

So excited to start my astrocyte journey with @holtlm90 & @EricJNestler!! 🧠

PS: hear all about it at Winter Brain this Sunday (5-7pm).

[Science Magazine @ScienceMagazine]

In Science, researchers report the observation of dendritic nanotubes in brain tissue from mice and humans. The discovery suggests that the current understanding of the brain’s organization may be incomplete, overlooking a hidden layer of connectivity.

Learn more in a new #SciencePerspective: https://t.co/Vv42SiBcif

[Samuel Hume @DrSamuelBHume]

The GLP1 weight loss medicine, semaglutide, is associated with lower risk of opioid overdose

Alongside the evidence for less urge to overeat, binge drink, and smoke cigarettes: GLP1s are emerging anti-addiction medicines

[Sachin Patel @SachinPatelLab]

📜📜📜: New lab paper many years in the making! BLA interneuron connectivity and function across fear conditioning and extinction….

Thanks to the whole lab for getting it across the finish line🍸 https://t.co/CE5zyRF9HR

[Journal of Clinical Investigation @jclinicalinvest]

GLP-1 receptor agonists for the treatment of alcohol use disorder: https://t.co/0bIwJS1fEw

@MayoOnTheBrain & @pact_lab provide a Commentary on Farokhnia et al. (https://t.co/onqVDzxHR5)

[Olivier George @brainaddiction]

Last night my brilliant friend with 20 years of expertise in Neuroscience including a decade at NIDA was fired because she was recently promoted for her outstanding performance and it triggered the probation period.

This is not making NIH more efficient, this is not making us healthier, this is not punishing the people who misled the public, this is destroying America’s talent.

Her work is instrumental for testing whether new medications to fight addiction are safe and efficacious before they are tested in humans. now that research is at risk.

She was the backbone of the lab the most senior person. So much knowledge, talent, know how, wasted, so much science destroyed for the wrong reason.

Sigh…

[Kay M Tye PhD @kaymtye]

Thats a great start!!
Let’s make it 50? Because every state has NIH supported research in it. Research is what gives you your medicine and technology and quality of life.

22 states sue to block Trump administration cuts to NIH research payments - STAT https://t.co/02JAzzKPs6

[Matt Hill @canna_brain]

Super cool new work from @DrFrancisLee demonstrating that boosting the endocannabinoid 2-AG may be able to taper the rewarding aspects of opioids without compromising their analgesic effects.

[Lauren Slosky @LaurenSlosky]

Can we design allosteric modulators that change a GPCR's preferred G protein? Yes!💥

BAMs at the GPCR-transducer interface change G protein subtype selectivity in predictable ways, enabling rational drug design.

The lab's 1st preprint! Check it out! https://t.co/ujSNQZsenV
🧵👇

[Drug Monkey @drugmonkeyblog]

A technician is a current and working scientist, not a future scientist in training.

#hilliwilldieon

[Matt Hill @canna_brain]

So for those of you interested in what it was that I took issue with in Hubermans first cannabis podcast, this is the Coles notes of the errors/inaccuracies that I noted. A lot of this is covered in the new episode, but some wont make it through and for others this is the TLDR

[Boris D Heifets @TheBorisLab]

In 2018, we (w @NolanRyWilliams) found that an opioid antagonist, naltrexone, blocks #ketamine's antidepressant effect. Is ketamine an opioid? What else does naltrexone do? We took these Qs into mice to get some answers, with @mCherryGarcia and many more https://t.co/JSkZoFX6Tp

[BryanRoth @zenbrainest]

'our results show the importance of using biosensors compatible with primary cells for evaluating the activities of endogenous GPCRs in their native environment.'
https://t.co/kEhWnnKeSM

[BryanRoth @zenbrainest]

This is a pretty astounding bit of work: discovery of Kir4.1 inhibitor as potential antidepressant
https://t.co/kRwaN2B4eJ

[nature @Nature]

Starting salaries at New York’s Icahn School of Medicine rise to $72,500 as part of a deal led by unionized researchers https://t.co/ObZ8qy2Ic9

[CLaE @leafs_s]

Nature Reviews Neuroscience

Causation in neuroscience: keeping mechanism meaningful
https://t.co/OeY3wfBJRR

[Alejandro Montenegro @aemonten]

"Based on these findings, the majority of PhDs would be financially better off if they skipped the postdoc entirely"

https://t.co/ejCnFB50pb

[Jason Sheltzer @JSheltzer]

Salaries in academia are never going to be as high as at DE Shaw. But I also think that academics need a significant salary increase, at all stages of their career trajectories.

[Scott Rich, Ph.D 🧠 @RichCompNeuro]

Morning radio show is playing “guess the salary.”

A postdoc comes on and makes a valiant effort to explain academia in 30 seconds.

Every radio host guessed the postdoc was making nearly 2x their actual salary.

Let’s fix that.

@AcademicChatter @OpenAcademics @thepostdoctoral