Alejandro Esclamado

PhD Student @thechaudhurilab. Mechanobiology in Development and Aging. MechE SGF @StanfordEng ‘27 | @ImperialBioeng '22 🇪🇸🇺🇸

[David Sinclair @davidasinclair]

Grateful to share our latest publication: We’ve previously shown age reversal is possible using gene therapy to turn on embryonic genes. Now we show it’s possible with chemical cocktails, a step towards affordable whole-body rejuvenation 1/17 https://t.co/J9c01lv5FQ

[Alejandro Esclamado @aesclamadoca]

@theChaudhurilab Congrats Frank and Dhiraj!!

[Dhiraj Indana @DhirajIndana]

Excited to share a preprint of my thesis work!!! Many thanks to amazing collaborators Andrei Zakharov, @ShenoyLab, Nidhi Bhutani, @Dunn_Lab and Youngbin Lim.
https://t.co/QwJMCkSA7C

[Alejandro Esclamado @aesclamadoca]

@MiroGasparek @sensible_bio @blueyard @Ginkgo This is amazing Miroslav, congratulations and good luck!!

[the Chaudhuri lab @theChaudhurilab]

Check out our latest review in @NatRevMCB on Cell-ECM mechanotransduction in 3D! w/ @aashrithsarasw1 @DhirajIndana https://t.co/VkZESo4Wh7

[the Chaudhuri lab @theChaudhurilab]

Stanford ME is hiring! We are looking for applicants for an Assistant Professor or untenured Associate Professor position across all areas of mechanical engineering. Check out our search ad here:
https://t.co/TYCOipuByt

[David Sinclair @davidasinclair]

Delighted to share with you our latest paper. Here, we test the hypothesis that aging may be driven by DNA damage-induced changes to the epigenome. Mightbe due to a glitch in the software of the body that causes it to malfunction, which can be fixed with a reboot?👇 1/

[David Sinclair @davidasinclair]

As cells divide they lose global DNA methylation, leading to a loss of cell identity and the replication of selfish DNA, which causes DNA damage and inflammation that may underlie cancer. Is it reversible? Should be https://t.co/gGQpBMG6x2

[the Chaudhuri lab @theChaudhurilab]

Another successful @StanfordSPLASH in the books! We had a great time teaching Intro to Mechanobiology to visiting high schoolers!

[the Chaudhuri lab @theChaudhurilab]

Lots of fun at Lake Nacimiento last weekend for our 2nd Annual Chaudhuri Lab retreat!

[Nature Biomedical Engineering @natBME]

Tendon degeneration alters nanoscale chromatin organization in tenocytes and impacts their mechano-epigenetic memory.

https://t.co/aUlSIdJ8TP

[Alejandro Esclamado @aesclamadoca]

@ProfTomEllis Setting aside the metric by which the govt assesses 'high potential', this seems like a great initiative. Why haven't the US or other countries introduced anything similar? Shouldn't one of our primary goals be to aggregate top talent that can supercharge the economy?

[Alejandro Esclamado @aesclamadoca]

@CNSdrughunter @JohnDoench Isn’t progeria due to a problem with nuclear lamins (not ecm laminins)?

[Lisa Feldman Barrett @LFeldmanBarrett]

The most expensive tasks that brains do are (1) moving your body and (2) learning something new. They have a metabolic cost that may feel unpleasant.

So, feeling bad doesn't always mean that something bad happened. You might just be doing something really hard.

[David Sinclair @davidasinclair]

Okay, this is a big deal: Vaccinations against aging work. Sure, it’s a proof-of-principle study in a rapidly aging mouse, but there’s little doubt this will be possible in us one day. Link👇1/3

[Jeff Karp (Pronouns: he/him/his) @MrJeffKarp]

The Modest Moderna Cofounder And Multibillionaire Robert Langer Shares His Secrets To Success https://t.co/QhCoBSgpwG

[Alejandro Esclamado @aesclamadoca]

@HyunwooYuk Would you have made a different choice 6 years ago though? Is this a call for change in the system or a word of warning to maybe consider other paths?

[Peter H. Diamandis, MD @PeterDiamandis]

Having known Elon Musk for 20 years, I’ve had the opportunity to watch his meteoric rise into someone who is arguably the greatest entrepreneur of our age.

Here's what EVERY exponential entrepreneur can learn from Elon. Thread.

[Alejandro Esclamado @aesclamadoca]

@ProfZhaoMIT Incredible, I can't wait to dive into the weeds. Thank you for putting this together!!

[Xuanhe Zhao @ProfZhaoMIT]

Soft Materials by Design: Unconventional Polymer Networks Give Extreme Properties https://t.co/QoTDQ5OLcG

#hydrogels #softmaterials #polymers #tissues #biomaterials #bioelectronics #bioinspiration #networks #fracture #fatigue #adhesion #conductive #magnetized #selfhealing