Afif Pranaya Jati

Facultative Bioinformatician,Ph.D. candidate at @LithgowLab @MonashBDI |PhageHunter|Klebsiella pneumoniae #KlebClub

[Phage Directory @phagedirectory]

.@afifpj (@MonashBDI) and colleagues published a new paper in npj Viruses on how highly stable #phages PIN1 and PIN2 have hallmarks of flagellotropic phages but infect immotile bacteria.

https://t.co/TLGMv1kjn8

[Afif Pranaya Jati @afifpj]

@SerieA_Lawas Bapaknya pemain Juve

[bioRxiv Microbiology @biorxiv_micrbio]

Hidden in plain sight: Bacterial genomes reveal thousands of lytic phages with therapeutic potential https://t.co/svrRco3FS2 #biorxiv_micrbio

[Andrew millard @milja001]

Want to find new lytic phages .... then obviously look in bacterial genomes !!! Led by
@TSPKU , with @MarthaClokie @panagouras3 , @bentpetersen and many many others...
https://t.co/css8fwnDKz

[Huiluo Cao 曹慧荦 @hlcao]

Klebsiella pneumoniae employs a type VI secretion system to overcome microbiota-mediated colonization resistance | Nature Communications https://t.co/P7c4inXQ4l

[Seth Bannon @sethbannon]

This isn't science fiction. This is real sequencing biotechnology just introduced by Roche. Wild and wonderful.

[Elliot Hershberg @ElliotHershberg]

Extremely clever new NGS tech from Roche 🧬

If it's hard to discriminate between nucleic acids accurately with a nanopore, why not synthesize a new polymer off a DNA template that is easier to sequence?

It's an intuitively simple idea, but took *a ton* of creative nucleic acid chemistry + enzyme engineering to design modified NTPs and create polymers of them.

It's been very interesting to see Roche move into the NGS market, and time will tell how this stacks up with the growing set of totally orthogonal approaches people are cooking up for sequencing tech.

It feels like we are entering another renaissance for biological measurement infrastructure—which is super important.

“Progress depends on the interplay of techniques, discoveries, and ideas, probably in that order." - Sydney Brenner

(These animations of sequencing tech will never get old to me. What a time to be a biologist!)

[Tominaga K. (tomiken) @pacyc1841]

LoVis4u: a locus visualization tool for comparative genomics and coverage profiles | NAR Genomics and Bioinformatics | Oxford Academic https://t.co/wRVDq4tmZq

[Mikael Skurnik @SkurnikMikael]

I am happy to tell that our collaborative review article on #PhageTherapy has been just published in Nature Reviews Methods Primers https://t.co/Te7YbdVMyG

[Rhys White 🧬 @RhysTWhite]

K. variicola can be misidentified as K. pneumoniae. Our #OpenAccess paper reports an outbreak in the NICU

📌The rapid detection of a neonatal unit outbreak of a wild-type Klebsiella variicola using decentralized Oxford Nanopore sequencing | @ARICJournal

https://t.co/CxLCyA0Vdu

[Stephen Turner 🦋 @stephenturner.us @strnr]

xOmicsShiny: an R shiny application for cross-omics data analysis and pathway mapping https://t.co/p5Tl02nvKb #Rstats 🧬🖥️🧪 https://t.co/toGgEsYArx

[Alexander Harms @AHarms485]

🚨 🧬 Updated preprint on the completed BASEL collection - what's new? Some fun with bacterial immunity and a new P22 relative infecting E. coli K-12. A thread 🧵

[Benagen-ONT @benagen3571]

genomics- A collection of scripts and notes related to genomics and bioinformatics
https://t.co/mm21MDigQu

[Jilong Qin @JilongQ]

Our recently work shedding light on the reason why most OAg in E. coli favoured the initial sugar with GlcNAc same to ECA structure is out! It is like a plumbing solution to ensure efficient recycling of the essential cell envelope building block, UndP
https://t.co/z3mmpS5kj0

[Ammar Zafar @az1980micro]

Our study appearing in @NatureComms showing the importance of the T6SS of Klebsiella pneumoniae in gut colonization. We combined tn-seq with metagenomics and identified new microbiota targets and T6SS regulators.
https://t.co/EmSdhvG7f1

[ASM @ASMicrobiology]

Enterobacterales with OXA-48-like carbapenemases are undermining the efficiency of carbapenem therapy. This review in @JClinMicro describes the genomic aspects underlying the rapid global spread of these organisms, and why they have become so successful. https://t.co/bqbsrwvesi

[Stephen Turner 🦋 @stephenturner.us @strnr]

Mining biology for antibiotic discovery https://t.co/i0nCnEGItL 🧬🖥️🧪

[good papers @paperperday]

Engineering Phages to Fight Multidrug-Resistant Bacteria

summarizes phage engineering techniques
https://t.co/RnMLGvxHf3

[bioRxiv Microbiology @biorxiv_micrbio]

Antibiotics that Kill Gram-negative Bacteria by Restructuring the Outer Membrane Protein BamA https://t.co/PKUNqGhAAx #biorxiv_micrbio

[bioRxiv Microbiology @biorxiv_micrbio]

From phenotype to receptor: validating physiological clustering of Escherichia coli phages through comprehensive receptor analysis https://t.co/8AmD3hgOFL #biorxiv_micrbio