Amy Walker Lab

Studying how metabolic pathways listen to environmental signals. Using worms, cells, and mice at UMASS Medical school.

[Amy Walker Lab @akwalker_lab]

@mengwang939 Can't wait to read it!

[Elizabeth Veal @ElizabethVeal9]

Exciting PhD project understanding how replicatively aged fungal cells contribute to antimicrobial resistance.

[Amy Walker Lab @akwalker_lab]

Let’s go worms!!

[Pukkila-Worley Lab is also @rpwlab.bsky.social @RPWLab]

Warming up on the Union Terrace for #MAPSS2024 The best worm meeting on Planet Earth!!

[Amy Walker Lab @akwalker_lab]

@Kavita_Babu_ @Sachin_mitosis @WormlockHolmes @smartelegans @VarshaS53228024 Thank you and all the other organizers! Super meeting, ran like a well-oiled machine, so much good science and community! #APWM2024

[Amy Walker Lab @akwalker_lab]

@WormlockHolmes @UMassChan Thanks and tagging @YAWormNerd86 Adwait Godbole who did much of this work! @ProgMolMed

[Amy Walker Lab @akwalker_lab]

@NinaSteele17 @Momademia In 2011 that was happening for me. Lab start + a difficult family split, with a teenager rather than a toddler. Survived and thrived with help from friends, family and the 🪱s. Feel free to PM, happy to provide a listening ear!

[Amy Walker Lab @akwalker_lab]

@StefPuig @UMassChan @UMassPsychiatry @NeurobioUMass Congrats on the lab move and the students! We are biased, but good choice!

[Amy Walker Lab @akwalker_lab]

@DrAndreaScharf Exciting! I'm disappointed that we aren't expected to have any in Massachusetts.

[Phillip J White PhD @phillipwhite14]

#METPHYS2024 @JBSpinelli is sharing a new key to unlocking the potential of the ETC

[Amy Walker Lab @akwalker_lab]

@ProgMolMed @UMassChanGSBS @guertin_lab @RDavisLab @UMassChan Congrats!!!

[Amy Walker Lab @akwalker_lab]

@RyderLab, super paper!

[Fruit Worms @fruitWormPapers]

The mex-3 3' untranslated region is essential for reproduction during temperature stress https://t.co/HESVATjgMw

[Amy Walker Lab @akwalker_lab]

@WormlockHolmes @iiscbangalore @GhoshRoyLab @Kavita_Babu_ @smartelegans @Sachin_mitosis Super excited for the meeting!

[Amy Walker Lab @akwalker_lab]

@millerlab

[Andrea Scharf @DrAndreaScharf]

Still looking for a MSC or PhD position for Summer/Fall 2024? The Scharf lab is hiring!
Come work with me on C. elegans populations and study aging!

[Amy Walker Lab @akwalker_lab]

@cmichSE @XanthaKarp Super news!

[Amy Walker Lab @akwalker_lab]

@ardemp @scrippsresearch Awesome Supriya!

[Amy Walker Lab @akwalker_lab]

@basktastic Thanks, we are excited about lipids in the Golgi!

[Amy Walker Lab @akwalker_lab]

@JavierApfeld @ScienceAdvances @ProgMolMed @UMassChan Thanks Javier, and for including the team! Awesome collaboration from all in the group.

[Amy Walker Lab @akwalker_lab]

(1/3) We are excited that our paper linking metabolism and regulation of immunity-linked genes is out in @ScienceAdvances, with an image highlighted on the front page!
@ProgMolMed, @UMassChan, https://t.co/XD0IRWAYyJ

[Amy Walker Lab @akwalker_lab]

@dweinkove @ScienceAdvances @ProgMolMed @UMassChan Thanks Dave!

[Amy Walker Lab @akwalker_lab]

(3/3) why these genes are so strongly unregulated in a pathogen challenge, since antimicrobial peptide production ramps up as well. Big shout to authors Matt Fanelli, @ChristoferWelsh, Lorissa Smulan and Dom Lui.

[Amy Walker Lab @akwalker_lab]

(2/3) We found that these genes are activated when the secretory system is stressed, which happens when lipid ratios are out of wack in the secretory system, when blocking the ARF-1 GTPase disrupts Golgi function or when secreted protein load is increased. This could explain