Extremely well-differentiated adenocarcinoma with a neuroendocrine tumor in the stomach. Intestinal metaplasia-like glands of the adenocarcinoma.
#GIpath#NET#MINEN
🚨We’re looking at the first reported primary cutaneous spindle cell sarcoma with FN1-rearrangement. Unlike other FN1-fusion tumors like PMTs and CCMNs, this one truly stands apart, making it a unique diagnostic challenge.
Read more: https://t.co/h60kEPsJcu
#dermtwitter#BSTPath
Happy Friday! Happy Holidays! I’m delighted to share this insightful review article, published this week in Histopathology @Histo_Journal , authored by Professor Yihong Wang and colleagues @DrSGraff Congratulations!
Summary: Recent advances in breast cancer research are unlocking new molecular applications for diagnosis & treatment. Personalized therapies like CDK4/6 inhibitors, immune checkpoint inhibitors, & PIK3CA inhibitors are reshaping care for hormone receptor-positive, HER2-negative cancers. Biomarkers related to drug resistance & the tumor microenvironment (TILs, PD-L1) are essential for treatment decisions. Integrating molecular data with pathology will lead to more accurate diagnoses & better outcomes.
The article is available at the following link:
https://t.co/fGwqnKUyoh
@BrownUCancer@BrownUniversity@BrownMedicine@BrownPathology@BrownOncology
Big combo from the small intestine:
Neuroendocrine tumor
Mucinous adenocarcinoma
T cell/histiocyte rich large B cell lymphoma
#GIpath#hempath#NEO#MINEN#THRLBCL
Acral fibrochondromyxoid Tumor (AFCM):
✅benign
✅very rare digital neoplsma, exclusively fingers and toes
✅ median age: 42 years
✅M>W
✅ may mimic chondroma and should be considered in the differential diagnosis
✅IHC:
➕EMA, ERG, CD 34
➖S100, SMA, SOX 10, PanCK