Today we report a new model system for the gut microbiome: hCom2, a defined community of 119 strains. @AliceCheng107 led the charge, with major contributions from Po-Yi Ho, @DrChilennial, and @SunitJain. Co-led by my longtime collaborator KC Huang. 1/22
https://t.co/EGr9EExTXp
NEW: With Helmsley funding, @StanfordBioE’s Dr. Fischbach and colleagues are developing therapeutic options to treat Crohn’s disease that could benefit the more than 2 million people suffering from the disease worldwide: https://t.co/XiHSBEfDjk
If you want to climb the unclimbable, be inspired here: @AlexHonnold
If you want to dream the undreamable, donate here: @UNITEDWEDREAM
And if you want to manage the unmanageable, well do I have an opportunity for you: 👇
https://t.co/mzgt5QoG0n
The final version of our DC genome editing paper is online @eLife https://t.co/4ybMhzPEnO ! If you've wanted to knock out genes in human DCs, take a look - we report a Cas9 RNP strategy that works quite well (generally >90% knockout). Co-led by partner in crime @alifescientist 1/
Many A. baumannii clinical isolates produce lipooligosaccharide (LOS) negative colonies after colistin selection. Though it’s thought that LOS is essential for viability it turns out that 2 compensatory mutations allow growth of LOS− mutants @mBioJournal https://t.co/yPep8dpZAa
We're excited to share two (2!!) new preprints from our lab now on @biorxivpreprint!
The first: "Human gut bacteria produce TH17-modulating bile acid metabolites" https://t.co/ejOXhmMmwF (1/2)
Check out our latest pre-print describing a strategy for CRISPR screens in human DCs and its use to probe how DCs recognize immune ligands (LPSs) from the microbome: https://t.co/eFnwGsWBHM
We are thrilled to announce @CarolynBertozzi as the new Baker Family Director of @Stanford_ChEMH!
Read the full announcement here: https://t.co/BUleXVgNR6
The bile acid pool, which recirculates between the liver and gut 10x/day, is central to metabolic & immune function. Its composition is heavily influenced by gut bacteria. Excited to share Masa/Tyler's work on the core pathway, w/🙏 to Almo for the collab. https://t.co/nM8tzAiqA4
We're looking for a scientific director for a new DARPA program in the area of microbiome therapeutics. Our lab + @Geneticdesigner and @Omar_Akbari_ . Job ad will be up soon; if interested, send me a note.
Congratulations to Baker Family Co-Director Chaitan Khosla on his election to @theNASciences! A well-deserved honor for an excellent scientist and leader @StanfordUChem@StanfordEng https://t.co/AOhpJBXCC9
Whitehead Institute announced today that the globally respected cell biologist Jonathan Weissman has become the Institute’s newest Member and will be the inaugural Landon T. Clay Professor of Biology at Whitehead Institute: https://t.co/yotLRQvgRq
Stanford ChEM-H and Wu Tsai Neurosciences Institute will host a joint scientific symposium on the occasion of the official dedication of the new ChEM-H and Neurosciences Buildings on Feb. 11, 2020!
To register, click here: https://t.co/HWCN2Zm2oo
@StanfordBrain
Soon, we will begin moving into the new Stanford ChEM-H Building, part of a joint research complex with @StanfordBrain. "The opening of this complex heralds a new era of scientific collaboration and discovery on campus,” says President Marc Tessier-Levigne https://t.co/NGsxIHBvJH
Join our quest for bacterial molecules that mediate microbe-host interactions!
We're looking for a postdoc with a background in bacterial genetics/biochemistry. You can email me directly for more information.
Please RT
@CCLRI@ClevelandClinic
We are seeking a highly motivated scientist to head our Metabolomics Knowledge Center!
To apply or for more information click here: https://t.co/Qn2vLIRaaD
In the newest ChEM-H Quarterly, we feature the new #Microbiome Therapies Initiative @Stanford, the prospect of a lifetime flu vaccine, and the intersection of chemistry and medicine with @lmkdassama! Read more and subscribe: https://t.co/IVyhmKpruP @CarolynBertozzi @StanfordMed
Excited to join the @Stanford_ChEMH operations team as the scientific program manager for @Stanford MITI! Check out the thread below for more info on the new initiative.
1/5 We are thrilled to announce the new @Stanford Microbiome Therapies Initiative. (That’s MITI, pronounced "mighty," for short.) The effort leverages the talents of @StanfordEng and @StanfordMed to advance what’s possible in #microbiome research. https://t.co/e6X3L2FHBU