Ali Ajam, MD

Postdoc @RazaniLab at UPMC/University of Pittsburgh | Cardiovascular Researcher | Interested in Atherosclerosis, Prevention & Procedure Outcomes

[Ali Ajam, MD @AliiAjam]

@RazaniLab @life_of_carlos @yushengyeh @Ziyang_LiuPhD @doureradjou @JunHuan70044527 Thank you so much for this great experience!🙏🏻

[Babak Razani, MD, PhD Laboratory @RazaniLab]

Fun times for @RazaniLab members with cameo appearance from Razani family to create 2 Marathon Relay Teams for the @PGHMarathon yesterday. Teams were appropriately called "#Lysosome Lightning" and "#FoamCell Fighters" 🤩. Guess which team won?

[Ali Ajam, MD @AliiAjam]

Excited to share my story in The Scientist’s Postdoc Portraits series—reflecting my journey from clinical medicine to translational cardiometabolism research.

🔗 https://t.co/3llxY74WzP

[Ali Ajam, MD @AliiAjam]

Honored to present at #AHA25 in New Orleans!
Grateful to share our work linking cholesterol, mTORC1, and immune dysfunction in residual CV risk.
Inspired by so many brilliant minds advancing cardiovascular science. Grateful to my mentor @RazaniLab for his guidance and support.

[Ali Ajam, MD @AliiAjam]

Honored to receive the Best Poster Award at Aging Institute Research Day 2025. Great to connect with so many inspiring scientists.
Thank you @RazaniLab @AgingPitt @PittDeptofMed — excited for what’s ahead!

[Ali Ajam, MD @AliiAjam]

Honored to present “Cholesterol-Driven Monocyte mTORC1 Activation and Autophagy Suppression in Hypercholesterolemic Patients” at #AHA25 in New Orleans, showing LDL-driven #mTORC1 activation & impaired autophagy may drive residual CV risk in #Atherosclerosis beyond LDL.

[Babak Razani, MD, PhD Laboratory @RazaniLab]

Check out our new commentary on #leucine and role in #CVD #atherosclerosis via #mtor #autophagy. Spearheaded by @XiangyuZ0321, @AliiAjam & @RazaniLab team we discuss next steps in limiting leucine's damage to the #macrophage & the atherosclerotic plaque.
https://t.co/m3rZuwe3IL

[Ali Ajam, MD @AliiAjam]

@HabibzadehMD Congratulations!

[Pradeep Natarajan @pnatarajanmd]

Among N=2530 w HeFH or ASCVD on max tolerated LLT with insufficiently low LDL-C (mean 98mg/dl), obicetrapib (CETPi) 10mg po daily v placebo led to 33% lower LDL-C at 3mo https://t.co/q5NTxK19F0 @NEJM @NewAmsPharma #EAS2025

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[EHJ Editor-in-Chief @ehj_ed]

Mitral annular disjunction is associated with a increased long-term risk of ventricular arrhythmias after mitral valve surgery
https://t.co/LGSYyJeJNF
#VHD #mitralvalve #cardiacsurgery #arrhythmias #cardiotwitter, @ESC_Journals, @escardio

[EHJ Editor-in-Chief @ehj_ed]

Pregnancy in women with a prosthetic heart valve: is considered high risk, primarily due to the need for effective anticoagulation: results of a large prospective registry published.
https://t.co/FS9itZQt64
#pregnancy #VHD #thrombosis #cardiotwitter, @ESC_Journals, @escardio

[Ali Ajam, MD @AliiAjam]

@AryaAminorroaya Thanks Arya jan!

[Ali Ajam, MD @AliiAjam]

Honored to present our study at both #VascularDiscovery #AHA2025 and #DOMResearchDay2025

From bench to bedside—a cinical study linking LDL-C, mTORC1, and autophagy in atherosclerosis.

Grateful to my mentor @RazaniLab, our team, and @AnumSaeedMD for her vital clinical insight!

[Ali Ajam, MD @AliiAjam]

@m_keykhaei Thank you!

[Babak Razani, MD, PhD Laboratory @RazaniLab]

Great showing by @RazaniLab at #VascularDiscovery25 in Baltimore the past 3 days. Kudos to the efforts of @KathyMartinYale, the entire organizing committee, & @American_Heart for the excellent programming & opportunity to present our work. See you all next year in Bellevue, WA!

[Ali Ajam, MD @AliiAjam]

@Naderian_mr Congratulations!

[Babak Razani, MD, PhD Laboratory @RazaniLab]

Wondered how #adipocyte #fat release #lipid via #lipolysis in #fasting, cold exposure? Multi-year @Razanilab effort in @jclinicalinvest by postdoc maven @yushengyeh identifies #lysosome lipolysis (LAL) as major way on par with known cytosolic route (ATGL)
https://t.co/ThtJuPgVUy

[ASCI @the_asci]

Spilling the skinny on fat cells!

ASCI member Babak Razani @RazaniLab & team @pitt_medicine discover the process for adaptation to fasting and cold-induced lipolysis involves lysosomal lipolysis: https://t.co/AQUSh8Bevq

[Ali Ajam, MD @AliiAjam]

@RForoumadi @MayoSurgery @Ali_Aminian_MD @marielariveram @TheNRMP Big congrats, Roham! As always, you were exceptional!

[Ali Ajam, MD @AliiAjam]

@Pouya_B95 @UMICHNeuroRes Big congrats Pouya jan!