Aging Institute at the University of Pittsburgh

Official account for the Aging Institute, part of @PittDeptofMed at @PittTweet School of Medicine & partnered with @UPMC. Researching the how and why of #aging

[Aging Institute at the University of Pittsburgh @AgingPitt]

The Aging Institute is pleased to share the Winter 2026 edition of The Chronos Chronicle, our official newsletter!

Learn more about all of the exciting research happening at the Aging Institute by clicking this link or by scanning the QR code below: https://t.co/QO683XOUEm

[Circulation @CircAHA]

Age-related vascular changes contribute to disease. What drives vascular aging and how can these insights lead to new therapies? @AgingPitt https://t.co/6hD2E2R9gp

[PittDeptofMed @PittDeptofMed]

The abstracts are in, the judges are ready, and the stage is set for the the Department of Medicine’s finest research on April 27 & 28 at the Pete! 🏟️

Register now to secure your spot for two days of discovery, awards, and a keynote from Dr. Wolfram Goessling.

🔗https://t.co/doWkN1MVlq

#DOMResearchDay #PittResearch

[Vascular Medicine Institute @PittVMI]

🔬 Join us at noon on Wednesday, February 18, for the next VMI/HVI Research Conference!

Dr. Shiori Sekine will present: "Functional cooperation between protein import and proteostasis in intracellular iron sensing at mitochondria"

[PittDeptofMed @PittDeptofMed]

A new @Nature paper by @JayXiaojunTan from @AgingPitt finds that a lipid called PI(3,5)P₂ binds to STING and is essential for activation in addition to cGAMP.

Read more about this study and other recent STING research by Jay Tan 👉 https://t.co/SiqvU97Vu5

#ResearchMatters #PittDOM

[PittDeptofMed @PittDeptofMed]

Your abstract ghosted us … so we gave it more time 💘

The deadline for abstract submissions has been extended to Monday, February 16, at 11:59 p.m.!

Groundbreaking research, just like true love, shouldn't be rushed.🔬❤️

🔗https://t.co/DHbZICC05M

#DOMResearchDay #ResearchMatters #PittMedicine

[PittDeptofMed @PittDeptofMed]

Abstract submissions are now open for DOM Research Day 2026!

Bench, bedside, or beyond – if it’s DOM research, it belongs at Research Day 2026 🔬🧪🩺

🗓 Deadline: Feb 11
🔗 https://t.co/7K4lyT5CIp

#ResearchExcellence #AcademicMedicine #HealthServicesResearch #H2P

[PittDeptofMed @PittDeptofMed]

Congratulations to Dr. Matt Steinhauser, who was recently promoted to Professor of Medicine with tenure in the Division of Cardiology and Aging Institute! 👏🎊👏

[PittDeptofMed @PittDeptofMed]

🍂🩺The Fall 2025 edition of Code Blue & Gold is here! 🔬🍂

Catch the latest news, discoveries, and highlights from the Pitt DOM 👉 https://t.co/UQvvSp8xI9

[Vascular Medicine Institute @PittVMI]

🔬 Join us at noon on Wednesday, September 17, for the next VMI/HVI Research Conference!

Dr. Andrey Parkhitko will present: "Targeting Age-Related Metabolic Dysfunction to Extend Healthspan"

[PittDeptofMed @PittDeptofMed]

Congratulations to Dr. Aditi Gurkar, who was recently promoted to Associate Professor of Medicine with tenure in the Division of Geriatric Medicine and the Aging Institute! 👏🎊👏

[Bokai Zhu lab @LabZhu]

Left by the tides | Pitt Med Magazine | University of Pittsburgh. A nice piece on our earlier work on identifying 12h rhythms in ‘free-living” humans. https://t.co/VsxEIGrDYI

[PittDeptofMed @PittDeptofMed]

🎇The summer edition of Code Blue and Gold, the University of Pittsburgh Department of Medicine's quarterly newsletter, has arrived!🎇

👀Check out all the recent happenings across the DOM in our latest issue 👉https://t.co/bOjsUP6Thk

[Jay Tan @JayXiaojunTan]

Excited to share our latest review "Lysosomal Repair in Health and Disease". We summarized how cells repair lysosomal damage via 4 distinct strategies and discussed the implications for aging, neurodegeneration, cancer, infection, and more.
Open access: https://t.co/Pg5wD5CBKC

[PittDeptofMed @PittDeptofMed]

Only 2⃣ weeks left until the 23rd Annual DOM Research Day!

Have you registered yet? If not, there is still plenty of time to register. Come discover the innovative research happening around the DOM!🔬🩺

Visit https://t.co/DHbZICC05M today to register and learn more about this year's event!

[PittDeptofMed @PittDeptofMed]

Read about recent @AgingPitt research including new insights on lysosomes from @JayXiaojunTan, biological rhythms from @LabZhu, and other geroscience breakthroughs in the @PittMedMag spring issue👇

[Pitt Med Magazine @PittMedMag]

The spring ’25 issue of Pitt Med is out! Look for:

👵 Age is more than a number.
🧠 Timothy Greenamyre unravels Parkinson’s mysteries.
🩺 Ideas to reality: Hearing hearts at home.

And much more. Read now:
https://t.co/i0wwlHjOA2

[Science Advances @ScienceAdvances]

Metabolic dysregulation is a driving force of aging.

Enzymes from lower organisms—such as bacteria and yeast—may be able to reverse age-associated metabolic changes in humans, a new study finds. @VFCracan @Scintillon @Aparhit @AgingPitt @PittDeptofMed https://t.co/6jsjozkLND

[Valentin F. Cracan @VFCracan]

Happy to share latest review which I wrote together with Andrey Parkhitko @Aparhit on how various enzymes from lower organisms can be leveraged to delay aging and age-related diseases. We discuss how genetically encoded tools we and others are developing can be used to target various aging-associated metabolic changes:
https://t.co/mMUuXjRCOU
@Scintillon @scrippsresearch @PittDeptofMed @AgingPitt

[Jay Tan @JayXiaojunTan]

Hormesis is everywhere, but particularly important on lysosomes. In this comment, I try to define 'Lysohormesis' as a mechanism and strategy for health benefits. Mild lysosomal stress is emerging as a way to avoid or delay many age-related issues. https://t.co/d22v3JXU2g