Andrew Luskin

in vivo veritas

[Sterling Crispin 🕊️ @sterlingcrispin]

This is one of the craziest ideas I've ever seen. He converted a drawing of a bird into a spectrogram (PNG -> Soundwave) then played it to a Starling who sung it back reproducing the PNG.

Using the birds brain as a hard drive with 2mbps read write speed.
https://t.co/f5gEyyK1MH

[Rhiana C Simon, PhD @mouse_braind]

Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇

https://t.co/3ZLg0EEStJ

[nature @Nature]

Nature research paper: Heterogeneous pericoerulear neurons tune arousal and exploratory behaviours

https://t.co/EKyLUh08Na

[Andrew Luskin @aluskin]

@SChenlab Thanks!

[Andrew Luskin @aluskin]

New paper on arousal in the brain! What controls the controller?

[Andrew Luskin @aluskin]

@willgiardino Thanks!

[Andrew Luskin @aluskin]

@baseliu Thanks Aiste!

[Andrew Luskin @aluskin]

@dilithium21 @mbruchas @_MadisonMMartin @kelseybarcomb @mouse_braind @gstuber @GuLiangcai Institutes include @UWAnesthPainMed, @UWPharmacology, @UWproteindesign, @seattlechildren, @UWPsychology , @UWBiochemistry, @CUAnschutz, @BioStructureUW - thank you all for making this possible!

[Andrew Luskin @aluskin]

@dilithium21 @mbruchas @_MadisonMMartin We worked on electrophysiology with @kelseybarcomb and Chris Ford; single-cell sequencing with @mouse_braind and @gstuber, spatial sequencing with Xiaonan Fu, Li Sun, Lei Gao, and @GuLiangcai; and 3-D imaging with Alexandria Murry and Sam Golden

[Andrew Luskin @aluskin]

@nabeelqu form determines function; neural processing is dependent on complex spatial/temporal dynamics - this is why neurons have different shapes, form different layers, etc. and many modulatory effects are not strictly synaptic but depend on volumetric release or spill-out effects

[Andrew Luskin @aluskin]

@nabeelqu ulkar nailed it but I'll add:
-easier to wire logically within biological constraints
-easier to learn/repair etc. bc adult neurons don't like to do huge morphological changes
-shorter transmission lengths increases speed, decreases size, decreases cellular stress in long cells