Rhiana C Simon, PhD

A.P. Giannini Postdoctoral fellow @ UCSF // Molecular profiling of the subcortical 🧠

[Mark Rossi @WhoIsMarkRossi]

Excited to share new work from the lab led by @YiLu72150820 highlighting the relationship between lateral hypothalamic glutamate neurons and acute overeating. We found unexpected sex differences that may explain why female mice are often resistant to diet-induced obesity.

[Malavika Murugan @muruganmalu]

Many decades ago Olds and Milner found lateral septum stimulation to be extremely reinforcing. In our latest preprint we explore why. Check it out and let us know what you think! https://t.co/TMu2S2tXTe
@jennisisaac @sonia_karkare @HymavathyB

[Garret Stuber @gstuber]

UW NAPE Center is hosting another outstanding imaging and genetics workshop this Fall. Geared towards new graduate students and postdocs. Please consider applying if you are interested!

[Weston Fleming @westonfleming]

How does the brain link a novel food to illness that happens later? We found that acetylcholine, released in part by parabrachial Calca neurons, can work through GPCRs in central amygdala to bridge the gap.

New preprint from @gstuber + Palmiter labs: https://t.co/thcod1hJE8

[Science Advances @ScienceAdvances]

A new study finds that both fear conditioning and antidepressant treatment stimulate new neuron growth in adult mouse brains, suggesting a possible adaptive response to stress-inducing experiences as well as elevated serotonin. https://t.co/kHjOmLf4sO

[UCSF Broad Stem Cell @UCSFstemcell]

Congratulations to Corey Harwell, PhD, on receiving a Neurobiology of Brain Disorders Award from the @McKnightFdn. His research explores how brain circuits develop and function, with implications for understanding neurodevelopmental disorders. #UCSFProud https://t.co/7WXSdjG5Lh

[Travis Goode @TravisDGoode]

Restaurants, billboards, commercials… what brain circuits link context to appetite? 🧠🍽️

Very happy to share a major update in our work on the hippocampus and lateral septum in calibrating food consumption! 🍩

Major thanks to our lab/collaborators! ⭐️

https://t.co/VEX5C2pzqV

[Rhiana C Simon, PhD @mouse_braind]

@muruganmalu @gstuber Thank you so much! So glad that it's officially wrapped up~

[Rhiana C Simon, PhD @mouse_braind]

Thanks to @westonfleming for the ephys, @brandy_briones for the behavior help, @KenIshii1223 and Sam Golden for the lightsheet data, and everyone else who chipped in along the way. Finally, thanks to @gstuber for his guidance and support throughout this project!

[Rhiana C Simon, PhD @mouse_braind]

Thrilled to announce that our paper is now finally out! 🎉We combine scRNAseq, 2p imaging, ephys, and behavior to understand the role of lateral septal Nts neurons in opioid withdrawal. Curious about the septum and addiction? Give it a read👇

https://t.co/3ZLg0EEStJ

[Andrew Luskin @aluskin]

New paper on arousal in the brain! What controls the controller?

[Malavika Murugan @muruganmalu]

Want to compare social and nonsocial reward seeking behavior? 
On STAR Protocols, we provide instructions for the assembly of a 2 choice operant chamber with an easy to use GUI-based acquisition system. Low cost and fully automated @STARProtocols https://t.co/wNEoY0hCVr

[Rhiana C Simon, PhD @mouse_braind]

I am thrilled to announce that I have been selected as an A.P. Giannini Postdoctoral Fellow! 🥳 Feeling fortunate to have received funding for my work on neurodevelopment of the lateral septum

[Dionnet Bhatti Mazo @victoryofflight]

Excited about our minisymposium at @SfNtweets ! Join us Wednesday afternoon to hear about the functional organization of lateral septum - from molecules to circuits and computations! Session details here: https://t.co/JcLSqVSN2J
#sfn2024

[mbruchas @mbruchas]

Chk out our newest collab paper co-led w/ @tpatriarchi, & others. We developed & characterized a nociceptin opioid peptide sensor. Congrats to Xuehan, @carriestineUW (student in my lab) who co-led effort. DM to try. @NIMH @NIDAnews @NAPECenter
Link: https://t.co/V27PRg0UNH

[Rhiana C Simon, PhD @mouse_braind]

Incredibly thankful to have had an opportunity to work on this project. I learned so much from @SodenLab and had a great time picking apart the VTA! Check out this thread to learn more about input specific regulation of VTA cell types 👇

[Yi Lu @YiLu72150820]

Thrilled to show my recent work about the regulation of dorsolateral septum GLP-1R neurons on feeding behavior. In this work, we showed that dLS-GLP-1R neurons and the inhibitory pathway to LHA can regulate feeding behavior.
https://t.co/T4PE13etlp

[Madelyn Hjort @BrainMadelyn]

Excited to share our methods work out in #Neurophotonics today! We coupled a new microprism design with a long working distance objective to track thousands of cells across days in the striatum.
https://t.co/A5JFkVTeel

[Harwell Lab @Harwell_Lab]

Please check our newest study on @biorxivpreprint - a tour de force led by the phenomenal @Chris_M_Reid, describing the diversity of neurons in the lateral septum in terms of transcriptomics, anatomical distribution, connectivity and electrophysiology: https://t.co/MQAtPvSBRH

[Antony Abraham @antabra]

Please apply to join my lab at Research Triangle Institute in North Carolina! We are seeking Ph.D. level scientists to join our team to work on mitochondrial mechanisms in substance use disorders. Apply here (or please RT/share):
https://t.co/VMbfUQEtPp