Our lab’s work profiling oncogenes and mutational order phenotypes in patient-derived organoids, is out as pre-print!
We highlight different routes of tumourigenesis, via chromatin and transcriptome profiling. Check it out!
https://t.co/LpykZnL5CD
🚀 New in Communications Biology:
Generative models of cell dynamics - from Neural ODEs to Flow Matching
https://t.co/6hEj5pchsg
We discuss modeling single-cell dynamics beyond snapshots: from cont-time Neural ODEs to simulation-free flow matching for scalable pop modeling.
We’re spilling the beans! The UK has developed its first crop of homegrown designer legumes.
Three newly developed varieties bring benefits incl:
- Improved gut health
- Increased food diversity and UK self-sufficiency
- Accelerated genetic techniques
https://t.co/QBg6AGG1ha
New research assistant position in our group working with Alex Gordon-Weeks. Interactions between somatic mutations and fibroblasts in liver metastases. #organoids#CRISPR#HPB
https://t.co/JBrMe3ZCS0
New post-doctoral scientist position in our group. @OpenTargets funded project in collaboration with Sanger and BRIC (🇩🇰). Multiomic analysis of response to chemoradiotherapy in rectal cancer.
https://t.co/bQ6GznEXc8
Our paper is out in @nature! This is from a @cshlbanbury meeting where a group of scientists got together to ask, can we ever identify the complete set of human genes? And how do we do that? with @elapertea@av_sparrow@carninci and many others https://t.co/YWXUcCAfFy
Excited to share #AlphaMissense our new AI system that can classify whether genetic mutations (missense variants) are benign or harmful - a critical step toward uncovering causes of many diseases, from cystic fibrosis to cancer. In @ScienceMagazine today https://t.co/pIsskIe1cP