Amit Mandal

Postdoc researcher. Smitten by genomics. Charmed by patterns in large-scale data.

[Amit Mandal @amit_49x]

Our lab’s work profiling oncogenes and mutational order phenotypes in patient-derived organoids, is out as pre-print!

We highlight different routes of tumourigenesis, via chromatin and transcriptome profiling. Check it out!

https://t.co/LpykZnL5CD

[Fabian Theis @fabian_theis]

🚀 New in Communications Biology:
Generative models of cell dynamics - from Neural ODEs to Flow Matching
https://t.co/6hEj5pchsg

We discuss modeling single-cell dynamics beyond snapshots: from cont-time Neural ODEs to simulation-free flow matching for scalable pop modeling.

[Cliff Pickover @pickover]

Mathematics.

Fractal Giraffe.
By Farley Katz, @FarleyKatz, https://t.co/jIFb3BR3pa, Used with permission.

[nature @Nature]

These are the 25 highest-cited papers published this century, and why they are breaking records

https://t.co/Y2eW4pbyko

[Tom Dörr @tom_doerr]

Resources for grant writing with AI

https://t.co/BU4DSc1C8e

[Amit Mandal @amit_49x]

The complicated legacy of antibiotics | Science https://t.co/LgxDNa5ilW

[Amit Mandal @amit_49x]

Fast and furious: mapping epithelial cellular turnover into intestinal transcriptomic atlases | Molecular Systems Biology https://t.co/FYPa2oY3PD

[Amit Mandal @amit_49x]

"APOBEC3A drives deaminase mutagenesis in human gastric epithelium"
https://t.co/VzW6d1BS11

[Amit Mandal @amit_49x]

The translational research journey in Cystic Fibrosis | 2025 Lasker award https://t.co/kXcDEPhwCy

[Biotechnology and Biological Sciences Research @BBSRC]

We’re spilling the beans! The UK has developed its first crop of homegrown designer legumes.

Three newly developed varieties bring benefits incl:

- Improved gut health
- Increased food diversity and UK self-sufficiency
- Accelerated genetic techniques

https://t.co/QBg6AGG1ha

[Simon Buczacki @SiBucz]

New research assistant position in our group working with Alex Gordon-Weeks. Interactions between somatic mutations and fibroblasts in liver metastases. #organoids #CRISPR #HPB

https://t.co/JBrMe3ZCS0

[Simon Buczacki @SiBucz]

New post-doctoral scientist position in our group. @OpenTargets funded project in collaboration with Sanger and BRIC (🇩🇰). Multiomic analysis of response to chemoradiotherapy in rectal cancer.

https://t.co/bQ6GznEXc8

[Steven Salzberg 💙💛 @StevenSalzberg1]

Our paper is out in @nature! This is from a @cshlbanbury meeting where a group of scientists got together to ask, can we ever identify the complete set of human genes? And how do we do that? with @elapertea @av_sparrow @carninci and many others https://t.co/YWXUcCAfFy

[Amit Mandal @amit_49x]

@tomgauld Good one!

[ErrantScience @ErrantScience]

The pile of things I have to read is now starting to bend space-time around it, but there's this new book that just came out... #reading #books

[Amit Mandal @amit_49x]

/STRs function as "rheostats" to control local TF concentration../
https://t.co/gD94fC8ZCr

Huge implications in understanding genome structure

[Demis Hassabis @demishassabis]

Excited to share #AlphaMissense our new AI system that can classify whether genetic mutations (missense variants) are benign or harmful - a critical step toward uncovering causes of many diseases, from cystic fibrosis to cancer. In @ScienceMagazine today https://t.co/pIsskIe1cP

[Nature Biotechnology @NatureBiotech]

The global patent landscape of mRNA for diagnosis and therapy https://t.co/utPcGuNd8P
https://t.co/TMBCZ5H832

[Tom Gauld @tomgauld]

My cartoon for this week’s @GuardianBooks / @GdnSaturday

[PHD Comics @PHDcomics]

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