A new living clinical guideline from @ACPIMPhysicians recommends #semaglutide and #tirzepatide as first-line options when initiating pharmacologic treatment with lifestyle modifications for weight management for nonpregnant adults with obesity. Read the full guideline: https://t.co/1Tbu4z60Kh
Could factor XIa (FXIa) inhibition change the future of secondary stroke prevention?
Hear experts discuss the science behind FXIa targeting and review key phase 2 and 3 trial data shaping this emerging approach to care.
▶️ https://t.co/uFr3A5jhde
The FDA has approved the first treatment for chronic hepatitis Delta virus (HDV): bulevirtide-gmod (Hepcludex).
Phase 3 data showed:
🔹 48% combined response at week 48 & more: https://t.co/bCYXPgSg08 #HDV
Research presented at #ERA26 highlighted new findings in chronic kidney disease (CKD), including evidence supporting more precise GFR assessment & trial results on finerenone in nondiabetic CKD & rivaroxaban in advanced CKD patients w/ CV risk factors. 👇 https://t.co/p4LQ9X9fh4
Survodutide led to significant weight loss in adults with obesity and without diabetes, according to results from the randomized, placebo-controlled SYNCHRONIZE-1 trial.
Learn more ➡️ https://t.co/6Mo4K4bzUn #CardioX
A new review of the evolving management of differentiated thyroid cancer highlights overdiagnosis of low-risk disease, dynamic risk stratification, active surveillance or ablation, targeted therapies, and active patient involvement.
Read the Review Article “Management of Differentiated Thyroid Cancer” by Laszlo Hegedüs, MD, Lori J. Wirth, MD, and R. Michael Tuttle, MD: https://t.co/0YKtWvwIEo
Try asking AI Companion to break this article down into teaching points for you.
GLP-1s are gaining traction in #MASLD and #MASH treatment.
New studies show:
🔹 Semaglutide improves MASH resolution
& more
More options may soon reshape liver disease care: [article-linik] #GLP1#Hepatology
https://t.co/ms0xHEbRsC
VitaK-CAC: Supplementation with the vitamin K homologue menaquinone-7 significantly attenuated coronary artery calcification compared with placebo in adults with symptomatic #cvCAD.
Get full details ➡️ https://t.co/7gBxg0pA5A #CardioX
🗝️ takeaways:
💉 Coadministration of #COVID19 and flu #vaccines may reduce MACE and mortality risk vs. flu vaccination alone
❤️ Risk reduction was strongest among older adults with comorbidities
@InfectDisNews@HealioPulm
https://t.co/iIVtoyYiLJ
Potassium: target or surrogate of optimized care in heart failure? Perspective in #ASNJASN argues that the POTCAST trial may reflect MRA intensification more than potassium targeting. https://t.co/d7aQI5OQpz
A new definition of MINOCA: from infarction
to injury. https://t.co/bIKCDyXaAG A new @EHJ paper proposes a vital update to #MINOCA: Myocardial Injury (not Infarction) with Non-Obstructive Coronary Arteries. This shift perfectly captures the "working diagnosis" phase, preventing premature diagnostic labels before advanced imaging confirms the actual cause. @ESCardio@ESC_Journals #NonObstructiveCoronaryArteries
Hipertensión Arterial en un punto de inflexión. 📈🫀👌🏻
🔷️La hipertensión está entrando en una nueva era: objetivos más agresivos y terapias dirigidas a mecanismos específicos. 👨⚕️🔎
🎯 Nuevas metas de TA:
✅ Las guías AHA/ACC 2025 establecen un objetivo universal de <130/80 mmHg.
✅ En pacientes con alto riesgo CV, se recomienda intentar alcanzar una PAS <120 mmHg, siempre que sea tolerado.
🎯Evitar mala adherencia, usar 2 fármacos de primera lina en una sola tableta desde estadio 2 (≥140/90 mmHg). 💊
🎯Nuevas vías terapéuticas:💊💉
1️⃣ Antagonismo dual de endotelina (Aprocitentan).
2️⃣ Inhibidores de la aldosterona sintasa (Lorundrostat y Baxdrostat).
3️⃣ RNA silenciador contra angiotensinógeno (Zilebesiran).
4️⃣ Denervación renal.
5️⃣ Obesidad & HAS (iGLP-1/GIP, Cx Bariatrica).
📄🆓️⤵️✨️State-Of-The-Art Review 2026 @JACCJournals 💯
https://t.co/Kgn9z2kNfD
https://t.co/oktV6loc8j
In the SNAP trial, cefazolin was noninferior to flucloxacillin or cloxacillin with respect to 90-day mortality in patients with methicillin-susceptible Staphylococcus aureus bacteremia and had fewer nephrotoxic effects. Read the full trial results and Research Summary: https://t.co/5Z39siPUhS