Our latest article in Nature (@Nature) reports the discovery of pathways to new polyene antifungals that outperform current clinical drugs and act via a different mechanism. Combating #AMR@imperialcollege
https://t.co/42W2nOEmiQ
BODIPYを脱水縮合でアミド化してプローブ化する論文。BODIPY側がアミンで基質がカルボン酸。縮合はDCC/DMAP。
#学ぶの論文紹介
Ready BODIPY-Tagging of Carboxylic Acids | The Journal of Organic Chemistry https://t.co/4Ndmg6ts5R
We are very excited to present our recent work, which just appeared in @ScienceMagazine (Ahead of Print) on a deconstructive synthesis strategy for efficient, programmable and stereocontrolled preparation of precisely modified macrocyclic skeletal analogs.
https://t.co/hMmPvtwG0x
A team applies their Glyph prodrug delivery platform to bypass liver metabolism and deliver allopregnanolone directly to the gut lymphatic system, achieving effective oral delivery in large animals and a phase one trial. @ScienceTM https://t.co/RtymxNev29
Modular Total Synthesis of Lasalocid Acid A through Direct C(sp3)–C(sp3) Attached Ring Construction | Journal of the American Chemical Society @ThomasBPoulsen https://t.co/BvbzOthNTw