Why most of our organs don't regenerate after damage? Have we lost the regenerative ability or can we enhance endogenous tissue regeneration?
In our @ScienceAdvances paper, we studied the MAPK/ERK signaling at the crossroad between fibrosis & regeneration https://t.co/egX74bj0ZE
Kudos to my colleagues for our study on inflammatory CAFs in PDAC. When MYD88+ iCAFs were depleted, tumor growth was reduced and T cell infiltration enhanced, suggesting that TME can shift from immunosuppressive to immunogenic for effective therapies👇 https://t.co/U8BaLnur0V
A baby named KJ, who was born with a rare genetic disorder – CPS1 deficiency – is healed thanks to doctors at the @ChildrensPhila who administered the world’s first personalized gene-editing treatment. The research team used base editing, a gene-editing method invented by HHMI Investigator @davidrliu and his lab at @Harvard University in 2016.
Earlier this year, Liu received the @brkthroughprize for developing both base editing and prime editing. These gene-editing technologies enable the correction or replacement of virtually any genetic mutation, including those that cause countless human genetic diseases.
Read more about Liu's work here: https://t.co/NlE25O7wJR
Choose Science. Choose Europe.
A new Marie Skłodowska-Curie Actions Postdoctoral Fellowships 2025 call is now open.
With a budget of €404.3 million, it will support around 1,650 researchers from Europe and beyond.
Apply by 10 September ↓
(1/2) Delighted to share our article in @Nature today on lung fibrosis! We used the histological architecture of lungs as a "map" to track biological factors that promote vs. resolve lung scarring across time and space.
https://t.co/E9hFfAbDGz
Biggest medical discoveries of the week (🧵)
1/10
Why does caloric restriction boost lifespan?
This study of ~1,000 mice finds (surprisingly) it's less to do with lowering fat mass, and more to do with boosting immune function and stress resilience
https://t.co/Qh58AyNNnT
Our latest paper is out in @Nature!
Hair follicle stem cells activate phagocytosis to clear apoptotic neighbours and maintain homeostasis👇🏼
Shout-out to Katie Stewart and everyone involded for the great work 👏🏼
https://t.co/kAU1n7fQVU
Our review on the Marvels of Spiny Mouse Regeneration is out! Discover the latest in spiny mouse research and their multi-organ regenerative abilities. Highlights on the ECM's role and combining ECM remodeling strategies with cellular therapies for new anti-fibrotic treatments👇
Humbled to receive a Rubicon Postdoctoral Grant from @NWOFunding
This further fuels my passion for science that remains a burning drive to explore new frontiers for effective treatments that can prevent and reverse tissue and organ fibrosis
https://t.co/3g36B3hWwB
Humbled to receive a Rubicon Postdoctoral Grant from @NWOFunding
This further fuels my passion for science that remains a burning drive to explore new frontiers for effective treatments that can prevent and reverse tissue and organ fibrosis. https://t.co/sm3UKWeTpp
Why do the brain appear wrinkly & resemble a cauliflower? Does the brain have a 'helmet'?"
We had the privilege of teaching 7th graders & answering their questions at this year's Stanford BrainDay about one of the most astounding organs 🧠
#ScienceIsFun#Stanford#BrainDay
Finally, it's out!!! Please read, enjoy, and share our latest publication on @Nature! One step closer to understanding progression in #MultipleSclerosis! Thanks to all the collaborators and to the @Pluchinolab
https://t.co/TzIPU2kq0g