Anzy Miller

Research Fellow, University of Manchester

[Anzy Miller @AnzyMiller]

To join our MRC funded PhD programme @FBMH_UoM apply before 15/11/24. #PhD #Stemcell #Oscillations #CellFate #CellDivision.

The impact of cell division on the decoding of oscillatory gene expression during neurogenesis at The University of Manchester on https://t.co/uP0xAKKlNo

[Anzy Miller @AnzyMiller]

Are you interested in exploring the interplay between dynamic protein expression and cell division, and how they impact fate decisions in neural development? We are looking for a PhD student to combine live imaging, optogenetics and data modelling. @BigaVeronica @TheAsheLab

[Papalopulu Lab @PapalopuluLab]

Our innovative study brings out the distinction between single cell and population-level #dynamic regulation. Single cell #oscillators can behave abnormally, despite this the population is normal due to cell #coupling mediated compensation. @Dev_journal
https://t.co/Mo0iGIrZIZ

[The Barker / Williams-Gray Lab @PDandHDLab]

The day is FINALLY here! The green light has been given by Swedish authorities for a first-in-human clinical trial with the stem cell therapy STEM-PD for treatment of Parkinsons disease! https://t.co/WgNC6SM4pf @ParmarLab @SCICambridge @BrainRepair_VGB @Kirkeby_Lab

[Teresa Rayon @t_rayon]

🚨we’re looking for a Postdoc (2-years initially) 🐭⌛️

📩 drop an email for further info

Closes Jan 31st

[Papalopulu Lab @PapalopuluLab]

!!Job advert alert!! We are looking for an enthusiastic postdoc with molecular biology expertise and a strong interest in developmental and/or cancer biology to join our team. Apply before Feb 5th:
https://t.co/IbgBMNs3mq

[Elli Marinopoulou @E_Marinopoulou]

We identified that the #SOX2 protein oscillates every 17h in proliferative and quiescent #glioblastoma stem cells. Interestingly, the #OscoNet algorithm predicted thousands more genes to oscillate 🤯
Our paper is out:
https://t.co/kvCHymYpAT

[Anzy Miller @AnzyMiller]

Yay my decoding NGN3 #oscillations paper is now in review, fingers crossed for a friendly reviewer 3 🤣

[Papalopulu Lab @PapalopuluLab]

How do cells decode #TF oscillations and how does this impact development? We find #NGN3 protein oscillates in #pancreatic endocrine cells, #oscillations are likely decoded via fold-change and impact on the timing of differentiation, but not fate choice: https://t.co/OYZSa3ryyU

[Papalopulu Lab @PapalopuluLab]

We are looking for a talented, self-motivated and collegial post-doc, with passion for #liveimaging, molecular biology expertise and a desire to understand the mechanisms of #cellstatetransitions in #development and #cancer. Apply before June 10th! https://t.co/3P4oL0aCRD

[The Ashe lab @TheAsheLab]

A new preprint from us! We use the SunTag system to image translation from single mRNAs in the Drosophila embryo and uncover translational regulation of the zygotic hunchback mRNA. Work by @DaisyJVinter, @Caro_Hoppe, Cath Sutcliffe, and @TomMinchington https://t.co/Q2uLvAkX7N

[Papalopulu Lab @PapalopuluLab]

In the latest preprint a phase-dependent relationship between Hes1 and cell-cycle is shown to underlie #cellcycle length heterogeneity in ER+ #breastcancer cells. Congratulations to the authors @nitin_sabherwal @Andyrowntree @JochenKursawe @papalopulu
https://t.co/iwotC4xbfg
1/6

[Tom Minchington @TomMinchington]

Excited to see that my first, first-author paper with @samgriffjon and @PapalopuluLab is now out! Do you work on dynamically expressed proteins? Probably. Check to see if your favourite transcriptional regulator features in our results.

https://t.co/DdR1X8CNL4

[Caroline Hoppe @Caro_Hoppe]

I'm excited to share my first first-author publication that is out now in @Dev_Cell. An exciting collaboration between @TheAsheLab, @MagnusRattray and @TomMinchington. We show how the Drosophila embryo decodes the BMP signaling gradient at single-cell resolution. (1/7)

[Papalopulu Lab @PapalopuluLab]

Cells in tissue are using ‘group chats’ to make decisions!

Multiscale synthesis of fine-grained protein expression of HES5 reveals locally co-ordinated clusters and stripes that control rate of progenitor differentiation.

bioRxiv: https://t.co/n5eLH6bHTq

1/5

[Herbert Lab @HerbertLab]

WE’RE HIRING!

Are you a cell or developmental biologist? Are you interested in how cells coordinate multiple processes during tissue morphogenesis?

Join our team! We’re looking for TWO new research associates!

https://t.co/5yu38XYaH7

#sciencejobs #postdoc @jobRxiv @the_Node

[The EMBO Journal @embojournal]

How do cells make cell state transitions? @PapalopuluLab @XimenaSoto40 et al reveal a #miRNA-driven mechanism counteracting noise and ensuring oscillatory expression of transcriptional regulators during #zebrafish neurogenesis
https://t.co/H0LshRT4zC

[Papalopulu Lab @PapalopuluLab]

Latest preprint by @TomMinchington @samgriffjon decomposes gene regulation into simple motifs showing that dual feedback motifs (auto-regulatory TF+microRNA) are prevalent and thus could drive dynamic expression in many genes found in human.

https://t.co/G8OprTKKRv

[DevBioManchester @DevBioUoM]

Exciting PhD opportunity with the up and coming PI of the moment Dr Guilherme Costa. If you are interested in RNA localisation, angiogenesis or ideally both then you should check out this fantastic opportunity: https://t.co/6qMtruwOrd