Caleb Appleton

Cyclist, coffee roaster, recovering triathlete and engineer. Deep tech investor at Bison Ventures. Always learning. Views are my own.

[Caleb Appleton @appleton_caleb]

@pdhsu @Stanford @StanfordPath @arcinstitute @BerkeleyBioE Congrats @pdhsu !

[Caleb Appleton @appleton_caleb]

@andrewpannu Congrats @andrewpannu and the full @sleuthinsights team!

[Andrew Pannu @andrewpannu]

We're launching Sleuth today.

The intelligence platform for biopharma's highest-stakes decisions, in use at top companies in the world.

To celebrate, we broke down the Chinese landscape: 18K+ assets & a map of the strategic white space. RT + comment "Sleuth" for access.

[Caleb Appleton @appleton_caleb]

@kevinweil Congrats on an epic run @kevinweil, hopefully more time for actual running now!

[Andrew Pannu @andrewpannu]

https://t.co/ZtcaoWs2wn

[Caleb Appleton @appleton_caleb]

@JonMSchwartz Agreed, obvious in hindsight. Jim Fan called it the integral of data types at Actuate and I thought that was a good way to frame it

[Caleb Appleton @appleton_caleb]

@benscharfstein I think it also probably tells you something about comp and comp structures at Anthropic and TML.

[Caleb Appleton @appleton_caleb]

@srikosuri @StJude Incredible news. So happy for you both

[EVCA @joinEVCA]

🥁 October Featured Investor: @appleton_caleb, @BisonVentures Caleb’s led investments in techbio & AI (@Vivodyne, @Cobot) and shares how a key career moment shaped his VC approach: https://t.co/NjDQqN55tF

[Caleb Appleton @appleton_caleb]

@eladgil Row34 for seafood and a great drink list

[Tim Walz @Tim_Walz]

Dropped by Georgia Tech to remind the Yellow Jackets to register to vote!

https://t.co/KwTi6hNP8Z

[Caleb Appleton @appleton_caleb]

@IanRountree Well, have you eaten?

[Caleb Appleton @appleton_caleb]

@PatrickMoorhead @AMD @LisaSu What do you think of the margin profile of ZT and the impact that has on AMD? Surprising to see this acq. at half of reported revenue suggesting a less than rosy GM.

[Caleb Appleton @appleton_caleb]

@adityaag I've been on a similar cadence (200 miles, 16 hours of ride time). For me the biggest value is the in car experience (music, AC) coupled with the smoothness of accel/deceleration; it means I can work on a laptop or take a call without fear of car sickness for first time in years

[Caleb Appleton @appleton_caleb]

@Sergiu_P_Pasca @Nature Congrats @Sergiu_P_Pasca !

[Caleb Appleton @appleton_caleb]

@neildevani We are!

[Caleb Appleton @appleton_caleb]

@McStempel ugh.

[Caleb Appleton @appleton_caleb]

@sfstandard If only it was to Billy Bishop it would be a true home run

[Caleb Appleton @appleton_caleb]

@LukeBornheimer I didn’t know Hansel but reading this brought tears to my eyes. Hansel seems to have embodied the ‘why I ride bikes’ that exists in all of us. The world needs more Hansels.

[Caleb Appleton @appleton_caleb]

@OpenJonathan They odds remain highly varied across a couple different wager sites. Good opportunity for someone to make a ton of money if they have conviction. Me, on the other hand, I’m just enjoying the internet drama and the possibility of something groundbreaking