We're launching Challenge 1 of the Anthropic x Adaptyv Protein Design Competition on @proteinbase: design a conditional binder to EGFR, a key cancer target.
The goal: bind EGFR under the acidic conditions of the tumor environment, but not at the normal pH around healthy cells. Moreover, the proteins must bind to both the human and the mouse variant of EGFR to support easier preclinical testing
To show what these optimizations make possible, we’re partnering with Adaptyv Bio on a protein design competition. Together, we’ll be experimentally validating over 5,000 designs.
We're providing up to $1 million in Claude credits plus funding alongside Adaptyv for experimental validation. Modal is contributing up to $250,000 in compute and Twist Bioscience is providing DNA.
Learn more on Adaptyv’s Proteinbase: https://t.co/KnjkWbH7zh
And sign up for the competition here: https://t.co/ytR2TAC3Vt
Biologists use specialized open-source models for tasks like modeling the structure of molecular systems, designing drug-like molecules, and predicting the effects of genetic mutations. But these models are often expensive to run, potentially limiting their impact.
In our latest Science Blog, we share how Claude was able to optimize inference for more than 30 open-source models, making them 4x faster on average, partly by writing custom software for GPUs. We’re open sourcing all of the optimization code.
Read more: https://t.co/qiuN1jpgpA
Introducing Gemini on Mac.
It’s the first time we’re bringing the @Geminiapp to desktop. The team built this initial release with @Antigravity, and it went from an idea to a native Swift app prototype in a few days.
More features on the way!
@amazonIN dear amazon india
I have ordered the items Arriving today KANPUR, UTTAR PRADESH
Order # 404-3193657-9048307
But we received the open package and there is no option showing for the return or refund, please see the attached screenshots and provide the full refund
@AmazonHelp How to connect while the Amazon server is showing error every time, now even if I want fetch the invoice info it's not showing anything,I hope based on order number your team can find the necessary details and proceed for the refund.cookie box was deliberately broken ñ consumed
Trained on 2M+ interaction complexes, ATOMICA learns atomic-to-molecular embeddings of interaction interfaces @AdaFang_
In the latest preprint:
🎯 Wetlab tests of AI predictions: Experimental validation confirms heme binding for 5 ATOMICA-predicted sites in uncharacterized proteins
🎯 Dark proteome illuminated: ATOMICA predicts 2,646 previously unknown ligand-binding sites, including zinc fingers and transmembrane cytochrome subunits
🎯 Disease insights: We built interfaceome networks (ATOMICANets) which connect proteins based on interaction similarity with ions, small molecules, nucleic acids, lipids, and proteins, revealing strong links between lipid networks and asthma, and ion networks and myeloid leukemia
https://t.co/WEeBIcmKuL
Chandrayaan-3 Mission:
'India🇮🇳,
I reached my destination
and you too!'
: Chandrayaan-3
Chandrayaan-3 has successfully
soft-landed on the moon 🌖!.
Congratulations, India🇮🇳!
#Chandrayaan_3#Ch3