Jesse Ashton

Recovering academic. From bench top neuroscientist to demand intelligence @predicthq. Dad 👨‍👧‍👦.

[Jesse Ashton @ashtonjesse]

I finished my first week as a Senior Data Analyst at PredictHQ, and I'm looking forward to sharing what the future holds for me there! Huge moment for me after spending 12+ years in biomedical science. Top thing I will not miss is the long hours at the bench away from family 💯

[Jesse Ashton @ashtonjesse]

@dgonzales1990 "you're gonna have to wrap yourself in tinfoil"

[Jesse Ashton @ashtonjesse]

@SMcfarnell What do you think is the implication here? Judging is an approximation?

[Jesse Ashton @ashtonjesse]

@AdrianoAguzzi This is the first tweet I've seen from you since your accident - happy to see you are alive!!!

[Jesse Ashton @ashtonjesse]

@hansmollman One of my best experiences in the US was at Pinecrest diner in San Francisco - love that place!

[Jesse Ashton @ashtonjesse]

@bryan_johnson You forgot don't have children that constantly wake up in the middle of the night

[Jesse Ashton @ashtonjesse]

Sincere thanks to our funders @royalsocietynz @HeartNZ and the Hynds Family Foundation, as well as support from @FMHS_UoA

[Jesse Ashton @ashtonjesse]

Huge congratulations to my other coauthors, the team at Auckland Hospital, and in particular my supervisor and collaborator Prof. Johanna Montgomery for having the vision and all the work required to make it happen.

[Jesse Ashton @ashtonjesse]

A lot of work was also done by my talented coauthor Ben Prince developing new techniques to image these neurons in 3D using tissue clearing and a new large volume imaging system developed @ABI_bioeng by Dr Greg Sands, Prof Bruce Smaill and others

[Jesse Ashton @ashtonjesse]

This suggests greater synaptic communication could underlie aberrant activity in heart neurons associated with episodes of AF. It also supports further investigation into ways to reverse this synaptic plasticity using stimulation techniques which may help prevent AF.

[Jesse Ashton @ashtonjesse]

Today we published the first of my last two papers! I am immensely proud of this one and hugely grateful to the tissue donors and their families. Here, we shed some light on how atrial fibrillation impacts heart neuron function in humans https://t.co/xfYKOF5YYs

[Jesse Ashton @ashtonjesse]

We recorded electrical activity from heart neurons using the patch clamp technique in intact groups of neurons. We show neurons from patients with AF have greater excitability and more synapses as well as changes in protein expression that could influence neuronal phenotypes.

[Jesse Ashton @ashtonjesse]

@iam_lpettingill @blarson424 What strong analytic skills were you looking for?

[Jesse Ashton @ashtonjesse]

@levelsio Are you feeding it any specific knowledge about CBT like in a RAG way or just relying on the base model? Could be a way to improve

[Jesse Ashton @ashtonjesse]

@visakanv Did you change your diet?

[Jesse Ashton @ashtonjesse]

@omaclaren Congratulations man! They finally came to their senses

[Jesse Ashton @ashtonjesse]

@tcarpenter216 Data-story telling skillz

[Jesse Ashton @ashtonjesse]

@SeattleDataGuy Yes please!

[Jesse Ashton @ashtonjesse]

@visakanv Definitely feel like I played house at academia some of the time. Having that laser focus is hard to keep up over long periods.

[Jesse Ashton @ashtonjesse]

@Mariintheworld

[Jesse Ashton @ashtonjesse]

@thdxr Yeah we came to the same conclusion after having trouble getting the pure vector search approach to work