balaganista

[balaganista @balaganista]

@salamasinamusic If anyone is looking for research on this topic, here are some papers indicating what USED to be normal was a toddlerhood peak of six or fewer infections per year (resp. AND GI), with the attack rate falling to 2-3 per year in school-aged children and 1-2 in adults. 1/n

[balaganista @balaganista]

My pinned🧵 provides evidence to answer the question, “how often is (was) it normal to get sick?”

Ex: In 2011, the textbook, “Bronchitis” defined ≥ 6 respiratory infections/yr RRI and therefore NOT NORMAL and only 6% of children younger than 6 had this many back then.

[chantzy @chantz_y]

Got this patient info sheet from the after hours clinic where my son went for an ear issue (not Covid, thankfully)

Apparently they are calling Covid a "common cold" now & normalizing kids being sick like 16 weeks of the year "without cause for concern" 😳

[balaganista @balaganista]

@pausedME @DiamonDie @C_Scheibenbogen Verapamil binds to α1. It has been a great med for me (was Rxed for tachycardia, but helps with cognitive function, food tolerance, even mood).

I don’t know anything about pharmacology but I thought I’d post here as it seems relevant and it’s cheap/available/reasonable safe

[balaganista @balaganista]

@DcrInYYC @JudahWorldChamp @jonstewart @jonfavs @Timodc @weeklyshowpod What dataset is this graph from? I only see the WHO part. Is it reported cases? TIA

[balaganista @balaganista]

@I_need_a_razor @Gmwetz Yeah when I was put on a vasoconstrictor to help me pump blood into my brain this symptom improved *dramatically*

Also various drugs with anti-inflammatory effects help a lot: ambroxol, verapamil, Spironolactone, antihistamines

[balaganista @balaganista]

@AndrewG76201347 @manruipa I also have reactivated EBV related to Long Covid and also have found spironolactone helpful--but since it works so fast for me (clears up the poisoned brain feeling <1hr), I figure it's more to do with its antipurinergic or ACE2-modulating effects than antiviral capacity.

[balaganista @balaganista]

@michaelzlin has your opinion on this changed since this thread?

Was exposed Thursday. Have had slight sore throat and congestion since yesterday (Sunday) morning. No positive RAT yet. If it were you, when would you start Pax?

[Michael Lin, MD PhD 🧬 @michaelzlin]

New study: Paxlovid rebound is much more likely if you initiate it within the first 2 days:

29% if started on day 1
17% on day 2
0% on day 3 or later

I had predicted such based on basic principles of immunity alone

https://t.co/0aKzPNyTAk

[balaganista @balaganista]

...and I mainly think that maybe the "diseases of civilization" are not due to sugar or even pollution but literally to civilizaton, as in: being crowded together in cities, spreading viruses that were never spread so far and so fast before.

People in the past knew that. 2/2

[balaganista @balaganista]

My education was in history, not science. I've been thinking a lot for the past few years about miasma theory, Victorians compulsively throwing open the windows/otherwise seeking ventilation, and other behaviors and beliefs of the past that now sound ridiculous. n/1

[Rachel Thomas @math_rachel]

The misleadingly named “Hygiene Hypothesis” is more accurately framed as the “Old friends hypothesis.”

We co-evolved with friendly bacteria & some parasites. We did NOT co-evolve with the *crowd infections* of mass travel, mega-cities, & indoor confines. 4/

[balaganista @balaganista]

@BaileyDevine20 Howdy

[balaganista @balaganista]

@loscharlos Yes, I am in the SW USA and I saw about half the staff masked at a big box store two weekends ago. Not so many customers. In this Progressive area it's usually 5%.

[balaganista @balaganista]

@HillcrestCardCo @CovidSolidarit1 Can confirm! I am someone who REALLY struggles with sticking out. Masking to protect what little health I have left is extremely hard for this reason.

Conformity is a safety thing for me (lifelong experiences as a member of a minority group taught me this).

[balaganista @balaganista]

@emiliesyverson @pot8um Yeah all my women friends (35-45) have some kind of inflammatory/immune ailment. My mom confirms it was not like this when she was this age. Maybe after menopause people would have HBP or be on thyroid meds. Multifactorial but mostly since 2021.

[balaganista @balaganista]

@krenzx Did you take a statin as well, or just the maraviroc?

[balaganista @balaganista]

@SplendidSpeseia WORD. Evil is literally what I say, too. There’s normal malaise, nausea, etc and then there’s the evil of a mast cell disorder.

So happy to hear of these improvements.

[balaganista @balaganista]

@BaltimorePeace @sheeza_blade “Researchers found that people ages 25 to 44 had about a 30% increase in heart attack deaths in the first two years of the pandemic. In fact, heart attack deaths rose most sharply in that age group compared to all other age groups.”

https://t.co/uVUhCNfyxP

[balaganista @balaganista]

@BaltimorePeace @sheeza_blade “1 in 5 heart attacks now occur in adults aged 40 or younger, a significant jump from just a decade ago when this age group accounted for only 1 in 10 cases.”

https://t.co/heqo8tkWbt

[balaganista @balaganista]

@SalvMattera I live in a large city in the SW US, near a big public university. I'm never the only masked person I see when I go out. There are more on the bus and in the pharmacy and library. But it's very rare among my bourgeouis clientele--my business is in a more affluent area.

[balaganista @balaganista]

@acrossthemersey @chantz_y @chaitrovert I just watched it and did not hear a peep about that C-word. Only Cancer.

[balaganista @balaganista]

@AlisonNolan9 @Naomi_D_Harvey I missed the discourse—people on here were talking about probiotics and ME? What was the gist?

[balaganista @balaganista]

@julieakincaid @useless_priest Yes, I would prefer to be invisible in general. Masking is socially VERY difficult for me. Just constant angst because rationally speaking it’s in my best interest but I hate standing out

Also I have a small business and it’s off-putting for sure