Epitalon gets thrown around as vague “anti-aging peptide” hype. What it’s actually doing: binding CAG/ATTTC repeats in the telomerase gene’s promoter and dialing transcription up, like a dimmer switch. It’s not editing your DNA, just telling more of it to express. 🧵
My single prediction for 2H26 in the peptide world:
Bacteriostatic saline becomes the new standard for reconstitution.
Not because it’s cheaper. (It is.) Not because it’s easier to source. (It is).
Because as people start paying attention to formulation science instead of simply copying what everyone else has always done, they’ll realize it’s often the better choice for many peptides.
Unlike bacteriostatic water, saline provides an isotonic, ionic environment that’s much closer to physiological conditions. Read: it mimics what’s inside your body already. For some peptides and proteins, that can mean better solubility, less aggregation, reduced adsorption to glass, and potentially improved stability over time.
I think we’ll eventually look back and realize most people in the peptide space are just singing from the same Jay Campbell/Hunter Williams song sheet (tremendous staring point by the way), and some of us will stand on the shoulders of those giants.
You heard it here first.
@ESPNInsights AR is SOOOOOOO lucky he got injured. People were talking about him getting max $, and he still might if people think this performance is b/c of the injury.
@sama How is this an update? “we’re going to be releasing some things someday, and some things after that. Some people will get some things, other people will get better versions of those things, and other people still will get better versions of those things.”
@bennyjohnson What a weird conclusion. Imagine telling someone from another timeline “In our timeline, sometimes our politicians make offhand kinda funny digs at other politicians!” Or maybe you wouldn’t tell them because it’s like… too braggy?
@KamalaHarris Two things: 1) This is clearly not a women’s rights issue, as it takes a biological man and woman to create an embryo, and IVF helps both men and women conceive equally. 2) @elonmusk clearly hasn’t fixed the bot issue, because any sentient human would realize this.
@sleepdiplomat theoretically, if a mid-30s male naturally gets 30-50 mins/night of n3 sleep, and when he takes Trazedone he gets 80-100 mins/night of n3 sleep, should he take Trazedone every night? This theoretical male uses at-home Polysomnography on a nightly basis.
@sleepdiplomat theoretically, for a mid-30s male, polysomnograph shows he naturally gets 30-50 mins/night of n3 sleep, and when he takes Trazedone he gets 80-100 mins/night of n3 sleep, should he take Trazedone every night? https://t.co/8mLikEr6H7
@EricJorgenson A front yard for neighbors to stop by without being intrusive. Outside actually comes with a lot of that stuff, anyway. And if you want to feel like you innovative, get a sign says “Generative AI Powered Lawn” and stick it wherever. Pro tip: include “LLM” on that sign, oh boy!
The “lean” concept based on a manufacturing process to build cars faster. This 1 concept tells you everything about how to create a car, for the entire history of cars, all the way back to riiiiiiiiiiiight after the moment the car was invented by Don T Worabadit
It’s not weird that the only advice you hear is: to build something that matters, you must first build the most basic v1 thing you can as quickly as you possible. Hegemony exists. It is kinda weird that it took Eric Reise 2 years to write the book this hegemony came from, tho…