Luiz Felipe Barella

Biotech Scientist - former @nih @niddkgov trainee - PhD, Islet Biology, GPCR, Gut-Brain Axis, Obesity, Alpine Skiing, Travel and IPAs

[Luiz Felipe Barella @Barella_LF]

Want to know more about beta-arrestin-1 (barr1), beta-cell mass and #obesity #diabetes? Thrilled to share that our paper is online now on @NatureComms! Beta-cell barr1 is essential for proper beta-cell function and mass @NIDDKgov @NIH https://t.co/JCj0tXitUJ

[Sai P Pydi @saip_pydi]

Thank you @biopatrika for highlighting our work!
We used single-cell RNA/ATAC-seq to comprehensively map how different cell types within the pancreatic islet communicate with each other, work that will help uncover new molecular targets for treating diabetes.@MolMetab

[SIMRAN SINGH @SimranSingh_26]

Thank you, @biopatrika , for the opportunity to share our research and for highlighting our recent work. It was a pleasure discussing our study and the science behind it. We truly appreciate your efforts in making scientific research more accessible to the broader community.

[Luiz Felipe Barella @Barella_LF]

@saip_pydi @MolMetab 👏👏👏

[Luiz Felipe Barella @Barella_LF]

Excited to see this paper out in @MolMetab ! Years in the making and such a great collaboration. Kudos to the whole team! 👏👏👏

[Sai P Pydi @saip_pydi]

Thrilled to share our new paper in @MolMetab ! 🎉
In this study we asked “what really happens inside the pancreas as obesity progresses?”
Temporal single-cell transcriptional dynamics of murine pancreatic isl... https://t.co/8051JlWjf5

[Sai P Pydi @saip_pydi]

Thrilled to share our new paper in @MolMetab ! 🎉
In this study we asked “what really happens inside the pancreas as obesity progresses?”
Temporal single-cell transcriptional dynamics of murine pancreatic isl... https://t.co/8051JlWjf5

[Sai P Pydi @saip_pydi]

Happy to share our preprint titled “ Myeloid Gi signaling acts as a weight-independent immunometabolic switch controlling systemic insulin sensitivity”. Here is the story!! #Immunometabolism #MacrophageBiology #GPCR #T2D #MetabolicDisease
https://t.co/92f89WJ85x

[Luiz Felipe Barella @Barella_LF]

@saip_pydi @Dharma_IITK @santhoshd22 @BioMeDHs @Quasarzafar Amazing! Congrats to all the team for putting such a great work together! 👏👏👏

[Sai P Pydi @saip_pydi]

Thrilled to share our new preprint “Acute activation of Gq signaling in islet macrophages inhibits β-cell insulin secretion through the AMPK–sphingolipid axis.”
Here’s how we uncovered a new immune–islet communication pathway (1/n)
🔗 https://t.co/zuyNsx7OAH

[Daniel J Drucker @DanielJDrucker]

The latest chapter from the "you can't outrun a cheeseburger" consortium. Analysis of energy expenditure across 34 populations implies dietary intake plays a far greater role than reduced energy expenditure in #obesity related to economic development https://t.co/1SCHtIvXl4

[Luiz Felipe Barella @Barella_LF]

Thrilled to have been part of this monumental project with great collaborators! Check out the thread below to learn how dynamic the mighty pancreatic islets are during the progression of obesity #obesity #diabetes #singlecell

[Sai P Pydi @saip_pydi]

Excited to share our preprint! “A Temporal Single-Cell Multi-Omics Atlas of Murine Pancreatic Islet Remodeling During Hyperglycaemia Progression” here’s what we found👇(1/n) #IsletBiology #SingleCell #DiabetesResearch https://t.co/wjEDH3YlAB

[Luiz Felipe Barella @Barella_LF]

@healthheronav @DanielJDrucker @jclinicalinvest https://t.co/ACQzPwQUqM

[Daniel J Drucker @DanielJDrucker]

The authors propose that α-cell enriched Gs-coupled receptors represent potential targets for modulating α-cell function/glucagon secretion for therapeutic purposes @NatureComms https://t.co/tzfFCUcWIF

[NIDDK @NIDDKgov]

Congrats to Dr. Jürgen Wess, Section Chief of Molecular Signaling in NIDDK’s Laboratory of Bioorganic Chemistry, for being elected a 2023 @aaas Fellow for his distinguished contributions to molecular and translational pharmacology. https://t.co/oCX3K9yZni

[Filip K. Knop @Filip_Knop]

In 🇺🇸, the prevalence of adult obesity increased from 30.5% in 2000 to 41.9% in 2020 (2030 projection: ~50%)😳
Prevalence highest among Black (49.9%) followed by Hispanic (45.6%), White (41.4%), and Asian (16.1%) individuals.

[Tatsuya Amano @tatsuya_amano]

How hard is it to do science in a language that’s not your first language? We quantified the severity of #languagebarriers for non-native English speakers when reading/publishing papers and attending/presenting at international conferences.
https://t.co/Z6za22rMgg
1/9

[Daniel J Drucker @DanielJDrucker]

GLP-1 #Weightloss #Obesity What's next instead of or in combination with the newer GLP-1RA via @NatureBiotech has some thoughts https://t.co/6gSmCJhk7E

[Luiz Felipe Barella @Barella_LF]

@CamilaLubac @KeystoneSymp @FractylHealth @harithr Great talk, Camila! 👏

[Frontiers - Endocrinology @FrontEndocrinol]

📣 Calling for contributions to our new research topic, edited by Dr. Renato Branco, Dr. @Barella_LF, Prof. Júlio Cezar De Oliveira and Dr. Isabela Iessi.

Want to contribute? Click here to get started 👉 https://t.co/ZS2UdkWSh0

[Dana Small @danamsmall]

The geographic overlap between BMI and life expectancy.

[Sai P Pydi @saip_pydi]

Non-White scientists appear on fewer editorial boards, spend more time under review, and receive fewer citations | PNAS https://t.co/4LuTHxYiGk