Bernard Carroll

Semi-retired research psychiatrist and now Equal Opportunity Critic

[Bernard Carroll @bcarroll40]

New outbreak of spat about FDA’s continuing use of ‘black box’ for antidepressants - this time on STAT. Comments are a must read. My take: it's an epistemologic quagmire caused by DSM-III. https://t.co/x2M3wBi6Qg via @statnews

[Bernard Carroll @bcarroll40]

As we await McCain’s interment,
Not forgetting Trump’s deferments,
The question arises
Who gives out the prizes
That give the nod of our preferment.

[Bernard Carroll @bcarroll40]

The sound of one hand clapping while putting lipstick on pigs: Ketamine, A Promising Depression Treatment, Seems To Act Like An Opioid https://t.co/79eBIWmPqE

[Bernard Carroll @bcarroll40]

United States woefully unprepared for nuclear strike, say scientists. Actually, we are woefully unprepared for a hell of a lot more than that. https://t.co/bu4ePGh6Ph

[Bernard Carroll @bcarroll40]

Oh, the company we keep! Half of the 2016 firearm deaths occurred in just six countries in the Americas: Brazil, the U.S., Mexico, Colombia, Venezuela, and Guatemala. h/t STAT

[Bernard Carroll @bcarroll40]

I have 3 new followers from USA last week. See https://t.co/JBlkcYEDvl

[Bernard Carroll @bcarroll40]

@AllenFrancesMD We don't need rocket science, but rigorous definitions of signs and symptoms, plus a numerate approach to their Dx weights. Neurologists are years ahead of us, e.g., with Parkinson's disease and look-alikes. Start here: https://t.co/zEss67Z2dM

[Bernard Carroll @bcarroll40]

Surrender Dorothy was the word.
Here’s Donald, too, now being spurred.
His name they’ve been scorning
On her bridge – not mourning –
One more step to his ending absurd.

https://t.co/vCvcCJ0fn2

[Bernard Carroll @bcarroll40]

Two examples of class, converging.

[Barack Obama @BarackObama]

Our statement on the passing of Senator John McCain:

[Bernard Carroll @bcarroll40]

A-plus for irony https://t.co/hWUIDWZgf7 via @theonion

[Bernard Carroll @bcarroll40]

Conveyor belt psychiatry or game changer? iTBS v rTMS are equivalent for MDD... but no active comparator. Are they both just placebos but just 3 mins v 37 mins per session? https://t.co/2fmgQozpg9 via @medscape

[Bernard Carroll @bcarroll40]

Parkinson's research has many parallels in mood disorders. But it's sad that this stale, boilerplate stuff on need for biomarkers is being recycled now. It's just hortatory handwaving. https://t.co/LAOYNpMwyu

[Bernard Carroll @bcarroll40]

@CoyneoftheRealm @JAMA_current @eturnermd1 You wouldn't be the first critics DeAngelis got nasty with.

[Bernard Carroll @bcarroll40]

You are conflating mere feelings and metaphysical posturing with clinical crisis due to delusions and cognitive impairment. Get to know these patients. When prevented from 'dying with their rights on' they will thank the front line responders who rescued them.

[Palliation Elixir @PalliationElix]

@psychunseen @deborahgeesling @bcarroll40 but are you not entitled to your own feelings without a huge intervention?
I read a quote earlier that said everyone is all about being there for the mentally ill but when they have a breakdown it's "toxic" they are entitled to their own feelings, same as you are.

[Bernard Carroll @bcarroll40]

@dawso007 Then the next step was when academics began forming their own corporations... arrrgh!!!

[Bernard Carroll @bcarroll40]

Where are the disinterested pioneer clinical scientists of yore?

[Allen Frances @AllenFrancesMD]

There's an enterprise-wide positive bias in medical literature.
Weak benefits are wildly hyped/serious harms buried.
We need better ways to extract signal from noise.
And more publication of negative studies.
#TMM

[Bernard Carroll @bcarroll40]

@PalliationElix @psychunseen There's a novel use of the whataboutism deflection. How about a substantive response now?

[Bernard Carroll @bcarroll40]

Here's an A-list of robust psychiatric syndromes with utility for Dx and prognosis: mania; BP I d/o; recurrent melancholia; disabling OCD; crippling anxiety; hebephrenic Sz; profound autism; more. We 'carve nature at the joints' to dissect these out by Guze-Robins method.

[Bernard Carroll @bcarroll40]

@PaulMinotMD Not at all... endo is a fine field. As for syndromes, I'll take them any day. Remember, Parkinsonism was a disease before it became a syndrome and now is multiple diseases. You can go a long way with syndromes without proving causation. What exactly do you want?

[Bernard Carroll @bcarroll40]

@seanmcarroll Gosh... I thought it was the circadian rhythm of plasma cortisol. And it's recurrent. :-)

[Bernard Carroll @bcarroll40]

@PaulMinotMD Not at all... endo is a fine field. As for syndromes, I'll take them any day. Remember, Parkinsonism was a disease before it became a syndrome and now is multiple diseases. You can go a long way with syndromes without proving causation. What exactly do you want?

[Bernard Carroll @bcarroll40]

A lesson for antipsychiatry diagnosis freaks... even where criteria seem clear and backed up by lab tests, the clinical process is fraught with uncertainty and delay. Dx is a moving target on reliability and validity. Time for you all to get real. https://t.co/w9PSOa5QVb