Here is our latest work in which we developed a method to map ssDNA contacts during DNA break repair in yeast. Homology search is not uniform along the ssDNA, the genome, and over time. We could define the mechanisms of its uneven expansion genome-wide🧵https://t.co/yepXyA8f7N
Interested in transcription and non-coding RNAs? Come join our lab @CBIToulouse to understand the regulatory function of 7SK snRNA during neuronal differentiation.
Only a few days left to apply for an ANR-funded PhD position: https://t.co/QJfpJS2e6b
Deadline : September 4th
Our latest review, spearheaded by @i_milagre on the suboptimal mitotic fidelity of human pluripotent stem cells. Many intriguing questions are still open! https://t.co/edvg3e24zB
A much-improved version (kudos to peer-review) of our exciting story on the link between sister chromatid resolution and removal of nascent transcripts in #mitosis is *now out* @emboreports https://t.co/zit9lox3ng
The @IJMonod is very proud to announce the election of Dr. Sandra Duharcourt and Dr.Katja Wassmann as new members of the @EMBO community.
This election highlights their scientific excellence and international reputation.
Congratulations!
@univ_paris_cite @INSB_CNRS
EMBO announces the election of 69 new members and associate members who join the EMBO community of more than 2,000 leading life scientists in Europe and beyond
https://t.co/vvu8lhuR5F
Single molecule interaction between human cohesin and CTCF - now in @Nature
https://t.co/sdFelsnvCs
A fantastic collaboration between Jan-Michael Peters' and the Cees Dekker lab to have a close-up look on those two major partners shaping chromosomes...
(1/n) The first paper from @EKimlab is now online in @Nature!
https://t.co/4kwUr2NZv8
Using single-molecule imaging, we reveal that Smc5/6 is a DNA loop-extruding motor. Upon ATP hydrolysis, single Smc5/6 translocates along DNA, while dimerized Smc5/6 extrude DNA loops.
Are you interested in chromosome structure and DNA repair/recombination?
Do you want to explore biological mechanism and develop your skills?
Come and join our team!
Two Wellcome-funded PDRA positions available with flexible start dates: Contact @LabNeale
https://t.co/BxTcCAB20Y
Pleased to introduce our latest preprint, out now: “Cohesin-mediated DNA loop extrusion resolves sister chromatids in G2 phase”. We present new quantitative assays probing the conformation of replicated chromosomes by imaging and high-throughput DNA sequencing. A tweetorial:
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