Belén López Morales

Licenciada en Biología.
Profesora de Biología y Geología.
Directora de ciclismo Nivel III.
ExCiclista profesional.
Metiéndome en líos desde 1984.

[CPA Women @women_cpa]

Hannah Ludwig, Riejanne Markus and Alessia Missiaggia are the #CpaWomen riders representative for #Durango Durango #Emakumeen Saria in case of application of the Safety and Extreme Weather Protocol during the race 🚴🏼‍♀️
#WeAreTheRiders #StrongerTogether #Cycling #WomenCycling

[Belén López Morales @belencycling]

@allory_d Fucking shit beta update. GPS stops working in my @Garmin edge 1050
@Garmin_Iberia

[Asociación Mujeres Imparables @mujer_imparable]

🙌Increíble #directo con la gran @belencycling, claro #referente del #ciclismo femenino y profesora de #Biología!

💪 A por el #CampeonatodelMundo de ciclismo Gravel en Nannup, #Australia!

https://t.co/vyBsaqDrN8

#MujeresImparables #InvisiblesImparables #Mujer #Deporte #Ciencia

[Asociación Mujeres Imparables @mujer_imparable]

👏 #InvisiblesImparables con @belencycling, #referente gaditana en el #ciclismo de élite❗

🕔 29.04, 17h. #Directo #Instagram https://t.co/TvZgKn4dVv

🙌 #Campeona de #España de Gravel en su categoría❗

https://t.co/Slu6dExRBp

#MujeresImparables #Igualdad #Deporte #Cádiz

[rotaaldia @rotaaldia]

Belén López se proclama campeona de España de Gravel en su categoría https://t.co/qUR3M4Enaz #rota #rotaaldia #RotaHoy

[CPA Women @women_cpa]

#DemiVollering is the best in #LBLwomen for the third time in her career 👏

#CpaWomen #WeAreTheRiders #StrongerTogether

📸 @SprintCycling

[Belén López Morales @belencycling]

Campeones de España de Gravel.
@TrikiBeltran en Máster 50B y yo en Máster 40A
#CEGravelAlcaraz26

[Belén López Morales @belencycling]

@ProCyclingStats @Amstelgoldrace @women_cpa

[🟥🟥⬛️ ProCyclingStats.com @ProCyclingStats]

What we love about @Amstelgoldrace is to see the women first and men later.

When we visit races with women after men most spectators are gone.

[Belén López Morales @belencycling]

@ciclo21 Gracias caballero!!!

[Ciclo 21 @ciclo21]

Hoy cumple 42 años Belén López @belencycling, primera #TOPCiclo21 a la mejor ciclista española del año.

¡FELICIDADES!

https://t.co/r4wCTihVCJ

[Iñigo San Millán @doctorinigo]

🚨After years of work along with major funding and institutional challenges, I am proud to share this new study showing how tumor metabolism, through lactate, actively shapes immune escape.

CONTEXT
PD-1/PD-L1 blockade, such as pembrolizumab, dominates current immunotherapy. However, its efficacy in most solid tumors remains limited, and the mechanisms underlying resistance remain poorly understood.

OUR STUDY
Using breast and lung cancer cell lines, we show that chronic lactate-producing metabolic states, rather than acute glucose exposure, drive tumor-lineage–dependent immune checkpoint gene expression. Tumors do not rely on PD-L1 alone. Instead, multiple immune checkpoints including CD80, CD73, VISTA, LGALS9 (Galectin-9), CD47, and PVR are coordinately remodeled in lactate-rich environments.

By experimentally separating lactate availability from lactate production using an extracellular lactate clamp, we demonstrate that lactate-conditioned immune features persist even when endogenous glycolysis is suppressed.

WHY THIS MATTERS
These findings indicate that immune escape is multi-checkpoint and metabolically conditioned through lactate, helping explain the limited success of single-checkpoint therapies. Our study highlights tumor metabolism as an upstream regulator of immune resistance and underscores the need to target lactate production and exchange, both within and between cells, alongside immune checkpoints beyond PD-L1.

(This one´s for you Dad🙏 🕊️)

https://t.co/0uvCGoiDKm

#CancerImmunology #Immunometabolism #TumorMetabolism #ImmuneEscape #Lactate

[Asociación Mujeres Imparables @mujer_imparable]

👏 Nueva entrega de #InvisiblesImparables!

💜 #Protagonista: @belencycling. Profesora de #Biología y #Geología. Directora de #ciclismo Nivel III. ExCiclista profesional.

🕔 22.04, 17h. #Directo #Instagram https://t.co/TvZgKn4dVv

#MujeresImparables #Igualdad #Deporte #Ciencia

[Marcos M. 🇵🇸 @euklidiadas]

¿Hay forma más bonita de ir a clase que en Bicibús Escolar?

[Belén López Morales @belencycling]

@PedalVintage Pirineos del Tour del 96

[Belén López Morales @belencycling]

Elegancia #Colnago hasta para escribir. #Mapei
@Colnagoworld

[Pedal Vintage @PedalVintage]

Aquí os dejamos el Podcast🎙️de esta semana: @gzlz11 entrevista al @TrikiBeltran. Esperamos que os guste:
https://t.co/GBeQxeBIfr

[Belén López Morales @belencycling]

@TrikiBeltran @PedalVintage @gzlz11 Qué vas a tener historias que contar tú? Si me han dicho que ayer casi no hablaste en el podcast 🤣🤣

[Track Piste @TrackPiste]

Nos ha dejado David Cabrero, un gran velocista, una extraordinaria persona. DEP
https://t.co/mcS7XYdSYy