Our lab at @TheCrick is looking for a Laboratory Research Scientist interested in bacterial genetics, #TB, #AMR, chemical biology, and/or high throughput screening.
Come work at a vibrant, collaborative research institute and help us #stopsuperbugs!
https://t.co/XSi7zlNvyE
Excited to share this new review! We surveyed the current state of art for bioenergetic inhibitors in Mycobacterium tuberculosis and we discuss how current models of antibiotic-induced cell death fail to adequately describe their mechanism of action.
https://t.co/8WhFwb81te
Hey everyone, I'm Tonya, a 6th year MD/PhD candidate @EinsteinMed. My research is focused on determining how inflammation affects plasma cell survival and function. This work aims to show how inflammation depletes pre-existing antibody titers. #BlackinImmunoRollCall.
When I entered med. school (no docs in fam), I assumed:
1 Med education would primarily train me to be a doc
2 Cancer screening is an unalloyed good
3 When docs recommend Rx, they knew those Rx work
4 Hours/ schedule worked were based on optimizing education
I was wrong x 4
Follow up: After we wrote about how @NYPDShea and his troops have stolen public space around stationhouses, @Vagoish discovered @NYPD26Pct has done it INSIDE Carl Schurz Park, inconveniencing @NYCferry commuters and raising the specter of racial bias: https://t.co/7ASRkTtceX
Now out in @ACS_Infectious: finding chemically distinct compounds against a single target in Mycobacteria, leading to mutually exclusive resistance alleles and collateral sensitivity.
Read free! #ACSEditorsChoice#RealTimeChem#AntibioticResistance
https://t.co/Qeq6P48wMa
When I started reading this, I thought it was going to be another version of the classic “physician becomes patient” essay.
It wasn’t.
If you teach students or residents, please take a moment to read this... and maybe my thoughts below, too.
(thread)
https://t.co/OwKrbpxoLV
Our lab member @tiagobeites published an article in nature communications regarding the "Plasticity of the Mycobacterium tuberculosis respiratory chain and its impact on tuberculosis drug development".
Do give a read!
https://t.co/GQKAH4TF1T
An exciting update!
We used the PROSPECT M. #tuberculosis chemical genetics platform to discover 2 distinct compounds💊 targeting 1 essential protein.
They're synergistic, AND resistance to either one can cause hypersensitivity to the other!
👇1/5
https://t.co/yKUA598EjZ
New publication from the Berney Lab! We found that the aspartate family biosynthetic pathway is a viable space for drug development. In particular, loss of threonine feedback leads to uncontrolled lysine biosynthesis suggesting a unique mechanism of death. https://t.co/Rlv4ZGPo4n
Such an exciting paper from basically everyone I know in TB research! Lots of promising new drug candidates, and what is this crazy essential efflux pump doing? Why would an efflux pump be essential?
https://t.co/jWo7Tijj7I
Soon, 3rd year M.D. students will join hospital wards. This week they've learned clinical, professional, and practical aspects of their new surroundings via workshops, meetings and hands-on exercises led by Einstein and @MontefioreNYC faculty and staff. #MedStudentTwitter#meded
Three Einstein M.D./Ph.D. students share what motivates them to pursue the long and rigorous road to becoming physician-scientists in this video about Einstein's Medical Scientist Training Program. https://t.co/TcvYI5MRid #MSTP#MedEd#science#PHD