Dr. Adrian Boström

MD, PhD | RTs, following≠endorsements | Views my own - not my employer | Father, forgive them; for they do not know what they are doing

[Dr. Adrian Boström @bostrom_adrian]

🌍💪 Amidst turbulence, it is important not to forget our progress as a species! 🚀 During the last century, basic sanitation improved, child mortality reduced, and GDP soared worldwide! 📈 Science's role is paramount in our advancements, and safeguarding its freedom is crucial.

Let's stand united against misinformation and bad scientific practices to keep the journey of progress going strong! 🌐🔒 #ScienceMatters #Progress #Humanity

[Tyler Black, MD @tylerblack32]

Ketamine flops when a psychoactive placebo is used. It could be that the entire effect was expectancy / unblinding.

[Dr Joanna Moncrieff @joannamoncrieff]

Article in JAMA on how over-diagnosis of autism is increasing and becomes 'a self fulfilling prophecy' and 'does not allow a child to develop their full capacity'. https://t.co/htVXJreiAk.

[Michael Ostacher, MD, MPH @RecoveryDoctor]

This study confirms (or is at least in line with) the idea that if you compare psychotherapies in a study with similar dose and duration of intervention that they all work about the same. Comparing a psychotherapy to "wait list control" is so biased that it should be illegal!

[Ash Paul @pash22]

Across the social sciences, half of research doesn’t replicate: Ambitious effort tested whether more than 100 papers held up on multiple types of “repeatability” tests via @JeffreyBrainard
https://t.co/4y8aJ7sMAp

[Ash Paul @pash22]

Half of social-science studies fail replication test in years-long project: Results from massive, ‘eagerly awaited’ initiative reinforce concerns about the credibility of science but raise hope for solutions. https://t.co/mcYb97OH7Q via @nicolakimjones

[George Kirov @GeorgeKirov1]

https://t.co/Go498zDofM

[Robert Howard @ProfRobHoward]

Our new paper in Nature Mental Health - why everyone treated with clozapine should be offered ACKR1 testing to identify individuals with benign neutropenia who can safely continue clozapine therapy.
https://t.co/u9mc24DIqz

[Allen Frances @AllenFrancesMD]

ECT is by far most effective/safest/fastest treatment for depressions that are: 1)very severe; 2)psychotic; or 3)unresponsive to meds.

Underused because of: 1)stigma; 2)misinformation campaigns; 3)poor access; 4)inconvenience; 5)neglect in training

See why my 1st choice for me:

[The BMJ @bmj_latest]

Swedish authorities are considering requests for “de-diagnosis services” for autism and ADHD from a new patient group: adults who no longer want their diagnosis
https://t.co/31BOnTb3nl

[JAMA Psychiatry @JAMAPsych]

Viewpoint: Patients with psychotic conditions often wish to stop antipsychotics, suggesting a shift to shared deliberation for collaborative management of associated risks. https://t.co/adUvZDfVUV

[James C.Coyne @CoyneoftheRealm]

"While several medications [for child obesity] demonstrated greater weight loss than placebo, the totality of the evidence was found to be inadequate. An important limitation of the pharmacotherapy studies was that there was only a single trial for each effective medication (ie, phentermine/topiramate, semaglutide, and liraglutide) that lasted longer than 2 months." https://t.co/fEqYmAVNK5

[James C.Coyne @CoyneoftheRealm]

NCI: Large analysis finds that for healthy adults, taking multivitamins daily is not associated with a lower risk of death. https://t.co/tTeZ4cCwRZ

[George Dawson @dawso007]

Don't know if others were aware of the passing of @CoyneoftheRealm a frequent poster here and elsewhere. Here is his obit https://t.co/0FZZrnPSvc

[JAMA Psychiatry @JAMAPsych]

Esketamine nasal spray as a monotherapy improved depressive symptoms in treatment-resistant depression (TRD) compared to placebo. https://t.co/qTTQmTerKA

[Chris Aiken, MD @chrisaikenmd]

Only 10-30% with bipolar take lithium, but 90% of experts in new survey rank it their top choice:
https://t.co/CQq2VAzOJW

Why? Better long-term outcomes, and addresses underlying causes of the disorder in new review by R Post et al:
https://t.co/CQq2VAzOJW

[JAMA Psychiatry @JAMAPsych]

Viewpoint: Target trial emulation can improve observational study validity by applying randomized trial design principles, but it is not a substitute for randomization.

https://t.co/nMtfMxA7tG

[Anisopoikilocyte @Anisocyte]

@DrLKVaughan @pash22 @YugShankar @UMAPsUK @NHSEngland @pa_StephenNash @lengreview @gmcuk @Adam_Skeen @AHill_PlymUni @bmj_latest There’s a real loss, I feel, in teaching medical reasoning at an early stage when you substitute with non-doctors, who do not possess medical reasoning.

You need that training to be able to link science back to the patient to start at the foundations of the degree.

[Oded Rechavi @OdedRechavi]

"A GO term analysis? how is this helpful?"

[TheLiftingShrink @psypharmacopeia]

Anti-psychiatry has plenty of brilliant minds who can tear the field apart with philosophy, rhetoric, and clever arguments. But none of that survives a single shift in a psych ER.