Brian Smith Lab

Laboratory of Brian C. Smith, Dept of Biochemistry, Medical College of Wisconsin @medicalcollege @mcwgradschool Opinions my own.

[Dr. Urrutia’s Precision Medicine Site @precision_ru]

Breaking News: A Feast of Genomics in 3D lead by Dr. Brian Smith, Co-Director, Structural Genomics Unit @MCW_Research @UDNconnect @RareDiseases @MCWPediatrics @MCWCancerCenter @Dr_R_Kurzrock

[Program in Chemical Biology @mcwchembio]

The Program in Chemical Biology is hiring a bachelor's or master's level chemist to join our highly collaborative team: https://t.co/Y1NFKGiV4P

[Brian Smith Lab @briansmithlab]

#Smithmigas #womeninscience #WomenInSTEM #InternationalWomensDay

[Brian Smith Lab @briansmithlab]

We're excited for our PBRM1 bromodomain inhibitor work to be featured in @PracticalFrag! A nice example of our @mcwchembio fragment screening pipeline. Thanks to @EmilyDykhuizen for cell work. @MedicalCollege @MCW_Research

[Practical_Fragments @PracticalFrag]

Fragment screening by NMR and optimization produces selective inhibitor for neglected bromodomain family VIII protein PBRM1
https://t.co/qZAPiQwyZz
@briansmithlab @nmr900 @MCW_Research @ACSPublications @JMedChem

[Brian Smith Lab @briansmithlab]

New Smith Lab from @MedicalCollege of WI publication in @ACSBioMed Journal of Medicinal Chemistry: "Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening" https://t.co/qDjQFD1huj
#bromodomains #NMR #PBRM1 #SAR

[Program in Chemical Biology @mcwchembio]

The Program in Chemical Biology at the Medical College of Wisconsin has opened a search for tenure-track positions. Review of applications will start October 14. For more details visit our posting in C&E News:https://t.co/ykFpPCaMLg

[Brian Smith Lab @briansmithlab]

Hot off the press from the Smith Lab at @MedicalCollege of WI! "N-terminal BET bromodomain inhibitors disrupt a BRD4-p65 interaction and reduce inducible nitric oxide synthase transcription in pancreatic ß-cells" https://t.co/YM6z0YNKDz #bromodomains #p65 #BRD4 #diabetes

[Brian Smith Lab @briansmithlab]

New publication from @Sprague_Dan of the Smith Lab - Trisubstituted Triazenes : the First Ligands of the sY12-Binding Pocket on Chemokine CXCL12 in @ACSMedChemLett https://t.co/7jygZGZcVz

[Medical College of Wisconsin @MedicalCollege]

Felice was the recipient of our 10,000th COVID-19 vaccine administered by medical student Natalie Yass. Learn more about the COVID-19 vaccines here: https://t.co/algiiBEtlq #ThisIsOurShot

[Medical College of Wisconsin @MedicalCollege]

Wearing a mask helps reduce the spread of COVID-19 when used in conjunction with other preventative measures, including physical distancing, frequent hand washing and cleaning high traffic surfaces. #WearAMask

[Brian Smith Lab @briansmithlab]

@Sprague_Dan You've got this!

[Brian Smith Lab @briansmithlab]

Cheers to the #TwoWomen scientists who won the #NobelPrize in chemistry today! Congrats @doudna_lab and Dr. Charpentier!

[Brian Smith Lab @briansmithlab]

Signal boost
https://t.co/wHielh0CDy

[Brian Smith Lab @briansmithlab]

New Smith Lab publication in Bio-Organic Chemistry - Novel activity-based probes targeting #sirt1, inspired by Cravatt lab #HDAC probes. Inaugural 1st-author paper for @mcwgradschool student @cjgoetz; teamwork by @Sprague_Dan.

https://t.co/LDVBF1aOcN

[Phil Bilodeau, MD @phil_bilodeau]

Why has no one thought of opening a bar near a hospital and calling it PubMed

[Joseph Kerschner @JoeKerschnerMD]

Excited to share that Dr. Robert Golden, Dean of @uwsmph and I crafted an op-ed in the Milwaukee Journal Sentinel on the @AAMCtoday road map to reset the nation's approach to the COVID-19 pandemic. This important message should be shared far and wide! https://t.co/au3X2t8fJq

[MCW_CardioResearchCenter @CVCatMCW]

Congratulations to our newest #NIH T32 postdoctoral trainees, Ryan Adam, PhD, Joshua Nord, PhD, and Michael Flinn, PhD @ivorbenjamin2 https://t.co/h2Ofk9woR5

[Allison Ebert @AllisonEbertPhD]

This is not a new idea, but it bears repeating. "All lives matter" is a worthless phrase until black lives are also included in the "all". #BlackLivesMatter

[MCW Graduate School @mcwgradschool]

“The new study does not ask why, but earlier research, including an analysis published last year by the NIH, has found that black applicants are more likely to propose studying health disparities, which are less likely to be funded by the agency.” https://t.co/9FosZhZseU

[Medical College of Wisconsin @MedicalCollege]

MYTH: Warm weather and heat can kill COVID-19. With all the information available about #coronavirus (COVID-19), it's important to separate fact from fiction.
For trusted information and resources, visit the MCW Coronavirus Resource Center at: https://t.co/algiiBEtlq #MCWCOVID19