#CARTcells for #DIPG#DMG clinical trial (1st arm) results are out today. Full Tweetorial coming, but first want to share the story of a patient whose #DIPG has disappeared for over 3 years. It is a milestone and moment of hope on a journey filled with so much grief.
“There’s a lot of loss that led to this research,” Drew’s dad said. “I hope those families know that this success is because of them.”
https://t.co/rNnHkL6pQR
Reconceptualizing behavior as a sharable reagent:
https://t.co/UUjOL6yDpf
We present a platform for behavioral analysis called Simple Behavioral Analysis (SimBA). A sincere thank you to the community for their continued expert feedback and suggestions
"To reduce pregnancy-associated mortality, evidence-based interventions are needed...along with nonpunitive approaches that incentivize pregnant and postpartum women to seek treatments for their substance use disorder."
Our paper out now in the journal Neurotoxicology: "Perinatal morphine but not buprenorphine affects gestational and offspring neurobehavioral outcomes in mice": https://t.co/FErmnxu0mG
"This work benefits both individuals using opioids and clinicians by adding to the knowledge base needed to make informed decisions about perinatal and infant care."
We used a buprenorphine dose on the lower end (but clinically relevant), that induced similar behavioral effects as the morphine dose used. Higher bup doses likely differ, making dose an important factor to consider.
The world expects us to play a role, and it wants us to look the part. Woman. Man. Mother. Wife. Breadwinner. Boss. Grandparent. Champion.
But the barbell — or the goal posts; the mountaintop; the finish line; even the top of your basement stairs — doesn’t care about your costume. All that matters is what you can do.
Like “move things from A to B and run fast and lift heavy,” says newly crowned Fittest Woman on Earth @laurahorvaht 🇭🇺. She earned the title with feats of strength and speed; technique and control; power and perseverance.
We all face scrutiny and stereotypes. We’ve all tried and failed at some point or another to fit into a mold we weren’t made for.
Maybe that’s why so many of us are drawn to sport. To physical conquest.
Barbells don’t un-lift themselves because you look like you shouldn’t be able to handle their weight. Miles aren’t discounted because you don’t “look like a runner.”
On the field and in the @CrossFit gym — and ultimately, in life — work is what matters.
And as Horvath says (and proved last week), “It’s amazing what our bodies can do if you put the work in.”
The best instructors do two things simultaneously when they teach. They come to the table with incredible expertise. But they also flip back and forth from the position of expert to the position of novice, as if they are learning it for the first time.