Danielle Buglak, PhD

Postdoc | Centrosome, nucleus, and video game enthusiast 🦓

[Danielle Buglak, PhD @BuglakDanielle]

Excited to share our recent work looking head-tail architecture in sperm!

[J Cell Science @J_Cell_Sci]

.@BuglakDanielle, Kathleen Holmes, Nasser Rusan and team investigate the role of the proximal centriole-like structure in maintaining nucleus–centriole architecture in sperm. #OpenAcccess #ReadAndPublish
https://t.co/7wLM751NJi

[Danielle Buglak, PhD @BuglakDanielle]

@LuskingL @nih_nhlbi @AlexKellyLab @OrnaCF @KateMiro1 Thank you so much for accepting the invitation! We had a great time with you

[VBautch @vbautch1]

So proud of our new study from the fabulous Molly Kulikauskas (@MollyKulikausk1 ) and the rest of the team! Alk1 signaling, like life, is a balance......

[Pauline Bougaran @PaulineBougaran]

A teaser of my first first-author paper which will be soon published in @atvbahajournals! 👀 Thanks a lot to my PhD supervisor @PascaleDufourcq and all the members of the @insermU1034 for their help! 🥳

[Brittany Miller, PhD @BK_Miller_Micro]

Attention soon-to-be and recent graduates: The Brennwald and Baker labs are UNC Chapel Hill are hiring a joint research technician! This is a unique opportunity to gain skills in molecular biology, genetics, and structural biology while working in two very supportive labs 🎉🔬

[Danielle Buglak, PhD @BuglakDanielle]

Check out our recent paper in @eLife! @vbautch1 @BautchLab

[eLife - the journal @eLife]

The nuclear membrane protein SUN1 stabilises endothelial cell junctions by regulating microtubule dynamics to regulate blood vessel formation. https://t.co/hm9WriKDGL

[VBautch @vbautch1]

https://t.co/hasLWY4crc @eLife
How does the nucleus communicate long-range to cellular junctions? Danielle Buglak (Bautch lab) and team show the way in endothelial cells and vessels - see our new paper just out in eLife!

[Danielle Buglak, PhD @BuglakDanielle]

@HaoYin20 Outside of junctional changes, we don't see major differences in the SUN1 KD cells following shear, but we haven't tried compression!

[Danielle Buglak, PhD @BuglakDanielle]

Thanks @HaoYin20 for the wonderful highlight of our work!

[Hao Yin @HaoYin20]

Nuclei-to-Cell periphery signaling in #SproutingAngiogenesis & VE-cadherin junctional dynamics

LINC complex SUN1/Nesprin1
Microtubule
GEF-H1 (RhoGEF)
Actinomyosin
VE-cad

How this is modified by #ShearStress🤓

Dr Victoria Bautch lab @eLife 2023 @vbautch1
https://t.co/t60JWt4Xeq

[Biomedical Picture of the Day BPoD @BPoD_s]

SUNny Sprouts - Role of #cell nucleus #protein called SUN1 in #blood vessel formation. Image & research by @BuglakDanielle et al @BautchLab @unc in @eLife. More on @MRC_LMS's https://t.co/4OrkQFFEik

[DisabledInSTEM @DisabledStem]

Shoutout to all the disabled women who persist in STEM every single day!! #DisabledInSTEM #InternationalWomensDay

[S Blitshteyn MD, FAAN, FANA, Dysautonomia Clinic @dysclinic]

Getting struck by a disabling chronic illness with no effective treatment in the prime of your life is a traumatic event of enormous impact. Nobody wants to hear that it's "benign" when your life is no longer as you knew it. We should avoid that word in #chronicillness.

[Bonnielin Swenor PhD @BonnieSwenorPhD]

A decade ago, I was 'kicked off' a research project bc the PI didn't understand how I - a person with low vision - could see my data. They said they would never trust my work. Today @NIH ACD passed landmark recs on disability inclusion. https://t.co/LxkUIgQAGT

[allisondraste is moving to 🦋 @allisondraste]

I hate that my chronic illness related fatigue is almost always understood in a work setting as being an inability to handle stress as if I am not a master at it

[VBautch @vbautch1]

Herculean effort from @MollyKulikausk1 with help from @ShakaX4 - great use of pandemic down time! So proud of you - congratulations!

[UNC Cytoskeleton Club @CytoskeletonUNC]

We also have some great posters focused on the interactions between cells from @BuglakDanielle (@BautchLab), @GladfelterLab, and @Anjanja1984 (@peiferlabunc)

If computational biology is your jam, then don't miss these two posters from the Elston Lab & @GladfelterLab!

[Hao Yin @HaoYin20]

Calculate #GiniCoefficient for your #EndothelialCell🤓

#LaminarShear (15 dyn/cm2 72 h @ibidiCells) increase HUVEC single-cell transcriptome heterogeneity

Genes+⏫Gini
-Translation
-OxPhos
-Adhesion

Dr. Victoria Bautch lab @atvbahajournals 2021 @vbautch1
https://t.co/wDxYOrdjrt

[Danielle Buglak, PhD @BuglakDanielle]

@ploostermelissa Thank you!

[Danielle Buglak, PhD @BuglakDanielle]

Very excited to share the preprint for my thesis work!

[VBautch @vbautch1]

Woo Hoo! Our first paper on endothelial nuclear-junction communication on bioRxiv - congrats to Danielle @BuglakDanielle and amazing team!
Nuclear SUN1 stabilizes endothelial cell junctions to regulate blood vessel formation https://t.co/JQQ6YSnaG6