Developmental Cancer Genomics. We study cancer and developmental biology using genomics and computing. PI @StAnna_CCRI | postdoc @CeMM_News | PhD @crm_edinburgh
🔬 At this year’s Long Night of Research, around 850 visitors joined us to experience the future of childhood cancer research. Through direct engagement, guests gained insight into how scientific ideas evolve into meaningful approaches for young patients!
🚨New paper! St. AnnaCCRI Researchers together with @CeMM_News uncovered a new strategy against leukemia: by collapsing the SAGA scaffold, the cancer-driving protein KAT2A breaks down, potentially halting leukemia cell growth. Published in @NatureComms👉https://t.co/lkc3L8TVn6
Our Human Multiomic Development Atlas paper is out in Nature today! A heart-felt "thank you" to all co-authors for their tireless work on this complex yet exciting project! Congrats all! https://t.co/iUiZz00KOt
New preprint from the lab!
How do tissue shapes influence cell fate decisions?
By manipulating brain organoid geometry, we show that lumen rounding directs apical progenitor division mode and promotes the emergence of basal progenitors.
https://t.co/nyPU8kJNpj
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🔍 Search a tissue image like a dataset?
CeMM PI André Rendeiro & team have developed #LazySlide, an AI-powered, open-source tool that links whole-slide pathology images to molecular data & enables natural-language search.
➡️ https://t.co/oORtsTzSnv
📄 https://t.co/A0SS7KN9d6
👋We are hiring a computational PhD student, interested in functional genomics and the non-coding genome. To continue developing our BRAIN-MAGNET algorithm recently published in Cell (https://t.co/r8uoZMZPfz). See vacancy for details!
https://t.co/QWoXjWHeNF
Excited to share another recent paper from the lab, in collaboration with @lucapinello and @danielevanbauer. We leveraged allele distributions after dense editing to identify the regulatory potential of individual nucleotides within #enhancers:
https://t.co/aTKlNX7P6U
INTERESTED IN SINGLE-CELL LINEAGE TRACING?
New review @NatureRevGenet from the @FraticelliLab. 🎉🎉
https://t.co/v3oa8gUUNj
With @VictoriaParreno we tried to update the modern manual for genetic tracing and clonal analysis. ENJOY!
Read link: https://t.co/amrOWuQvVs
Happy to share our paper in collaboration with the Halbritter group (@cancerbits). We used machine learning & ATAC-seq to refine erythroid differentiation protocols. Recipes for lineage differentiation are written on chromatin!
👉 https://t.co/s6MAJh9pZY
@StAnna_CCRI@CeMM_News
📢 New paper alert!
A research team led by @cancerbits and @DSeruggia developed a new method that helps scientists craft more accurate cellular models from stem cells. More: https://t.co/ZnOn7NN9ki
📢 New paper alert!
A research team led by @cancerbits and @DSeruggia developed a new method that helps scientists craft more accurate cellular models from stem cells. More: https://t.co/ZnOn7NN9ki
In Focus: Raising Awareness of Tremendous Progress and Ongoing Challenges in the Fight against Childhood
and Adolescent Cancers https://t.co/SZpjHoGnrL
By Samara L. Potter and Elaine R. Mardis at @nationwidekids@OhioStateMed
🎗️#InternationalChildhoodCancerDay! Every year, around 400,000 children worldwide are diagnosed with cancer. Progress is possible: through research, international collaboration and close cooperation between science and clinical care. Read more: https://t.co/LinJLC7CVH
Deadline approaching!
3 more days to apply to our consortium!
I am looking for a PhD student interested in combining experimental systems biology and high-throughput assay to investigate memory formation in epithelial cells across organs.
Details here: https://t.co/ZFcaIVegBz