Caolann Brady

DPhil in Clinical Medicine, University of Oxford @Carroll_Lab_Ox

[Caolann Brady @caolann_b]

Proud to share that our manuscript was published this week in @Nature_NPJ Vaccines! This paper is the first instalment of my PhD work on a project that I was very lucky to be a part of

[Carroll Lab @Carroll_Lab_Ox]

📣Publication alert 📣
A novel study in npj Vaccines by @caolann_b defines immune correlates of protection (CoPs) against SARS-CoV-2 using systems immunology and machine learning tool (SIMON) in 90 macaques across 4 vaccine platforms. Thread with key findings below 🧵
@PSIOxford

[Adriana Tomic @TomicAdriana]

🚨 New Paper Alert! 🚨 Just published in @npjVaccines!
We used our #AI/#ML platform #SIMON 🤖 to define #SarsCov2 correlates of protection using preclinical NHP data. Great collab w/ @Carroll_Lab_Ox @UniofOxford, led by @caolann_b!

Key findings:
✅ Antibodies🛡️ best predict clinical protection.
✅ T-cells💪 + Abs🦠 predict viral control.
🤔 Protection ≠ Viral Control!

Learn how AI helps decode vaccine immunity 👇
https://t.co/CAmAYaTeKL
#COVID19 #Vaccines #AI #MachineLearning #Immunology #SystemsVaccinology #CorrelatesOfProtection #AtomicLab

[Carroll Lab @Carroll_Lab_Ox]

📣Publication alert 📣
A novel study in npj Vaccines by @caolann_b defines immune correlates of protection (CoPs) against SARS-CoV-2 using systems immunology and machine learning tool (SIMON) in 90 macaques across 4 vaccine platforms. Thread with key findings below 🧵
@PSIOxford

[Caolann Brady @caolann_b]

Congratulations @hannahjklim! Very impactful research - I’m very lucky to have worked with you on a minor part of this project 💕

[Carroll Lab @Carroll_Lab_Ox]

New paper led by our former DPhil student @hannahjklim out now in @NatureComms ‘Serological analysis in humans in Malaysian Borneo suggests prior exposure to H5 avian influenza near migratory shorebird habitats’

Some media coverage in the thread below

https://t.co/HvV5ybdGlg

[Caolann Brady @caolann_b]

Excited to share that I passed my DPhil viva yesterday! I’ve learnt so much in the last 3 years and I’m very grateful for all of the input and encouragement I received! I’m feeling very inspired for the next phase of my research career while studying medicine at @UniofOxford!

[Carroll Lab @Carroll_Lab_Ox]

Congratulations to @caolann_b who passed her DPhil viva yesterday! Thanks to Prof Helen McShane and Prof @ChrisChiuLab for being viva examiners

Caolann is now starting medicine @UniofOxford and we wish her all the best in her career!

[Petter Brodin @BrodinPetter]

New paper out @Nature - why are males more vulnerable to severe infections (ex acute #COVID), while females suffer more from autoimmunity (SLE, MS etc and also #LongCovid)? sex chromosomes or hormones?

Here we studied adaptation of human immune systems to gender-affirming testosterone treatment in trans-men assigned female sex at birth: https://t.co/HzCQI6GUwn

[Caolann Brady @caolann_b]

It was great to be back in Dublin this week for academic reasons at #ECI2024 - I learnt a lot! It was great to give the final presentation of my PhD, back where it all began!🇮🇪

[Charlotte Summers @charlot_summers]

So, @bykatewomersley @marinadpol and I wrote something.... please take a look!

Changes to the UK foundation programme add further challenges for doctors pursuing clinical academic careers https://t.co/SxBrakD16h

[Caolann Brady @caolann_b]

We made a micro-documentary - please give it a watch and share! Thank you @OxfordSparks @PSIOxford and @ReubenCollege for supporting our project!

[OxfordSparks @OxfordSparks]

Pandemics: The Unanswered Questions

Researchers @CillianGartlan, @caolann_b, @hannahjklim and @gracehood_ explain the science behind the public's Covid-19 questions, including the likelihood of future pandemics and why many viruses come from bats.

🎥https://t.co/5KRsai72Qf 1/2

[Caolann Brady @caolann_b]

Thank you @iuis_online for organising a fantastic conference in Cape Town! I thoroughly enjoyed meeting so many great scientists and engaging in exciting discussions #IUIS2023

[Cillian Gartlan @CillianGartlan]

Some behind-the-scenes from our upcoming micro-documentary with @OxfordSparks ‘Pandemics: The Unanswered Questions’. Stay tuned!

This is part of a public engagement project made possible with funding from @ReubenCollege and @PSIOxford

[Carroll Lab @Carroll_Lab_Ox]

DPhil students @caolann_b and @CillianGartlan presented posters and talks at the @JennerInstitute DPhil symposium hosted @sthildas_events yesterday

[Cillian Gartlan @CillianGartlan]

Last night we debuted a new public engagement project called ‘Pandemics: The Unanswered Questions’ @morethanadodo as part of the ‘Connected Worlds’ event. We really enjoyed discussing all things pandemics!

Stay tuned for more on this project! @gracehood_ @caolann_b

[Cillian Gartlan @CillianGartlan]

Myself and the other PhD students in @Carroll_Lab_Ox (@caolann_b, @gracehood_ and @hannahjklim) will be debuting a public engagement project we’ve been working on at this event!

It’s called ‘Pandemics: The Unanswered Questions’ and is funded by @ReubenCollege and @PSIOxford

[Caolann Brady @caolann_b]

The first publication of my DPhil is out now! This review article provides the rationale for the experimental work of my DPhil. I hope to see correlate of protection investigation being more frequently included in studies involving animal challenge models! Thread and link👇

[Carroll Lab @Carroll_Lab_Ox]

New review article by our DPhil student @caolann_b titled ‘Pre-clinical models to define correlates of protection for SARS-CoV-2.’ @FrontImmunol https://t.co/aePolG6xUm

Thread below🧵#vaccineconversations @britsocimm

[Carroll Lab @Carroll_Lab_Ox]

New research article by our DPhil student @hannahjklim showing how environmental and land use factors can be used to model high-risk regions for probability of exposure to potential zoonotic reservoir species. Short thread below🧵#spillover

[Carroll Lab @Carroll_Lab_Ox]

Carroll Lab Christmas dinner 2022! 🎄

Missing a few members; @stephanie200586 @TomTipton3 @gracehood_ and Dung!

[Caolann Brady @caolann_b]

Thoroughly enjoyed presenting my first year DPhil work at #BSI22 - thanks to @bsicongress for accepting my abstract. Really appreciated the engagement and questions - thank you to @Leo1401j and @jenneratingVacc for chairing such a great session!

[Carroll Lab @Carroll_Lab_Ox]

Brilliant talk from @caolann_b showcasing her work on SARS-CoV-2 correlates of protection #BSI22

[Caolann Brady @caolann_b]

@TomicAdriana @Carroll_Lab_Ox Thanks @TomicAdriana for all your help!