I am excited to share our preprint! we use synthetic human gut communities to reveal crucial ecosystem-level dynamics that drive major gut microbiota signatures. Thanks to the support of @MoualiYoussef and Strowig lab https://t.co/asWhZLmHJ1
Very excited to share our paper!! If you are interested in how our gut microbes have changed with the modernization and industrialization of our lifestyles check it out! @cellhostmicrobe https://t.co/ZAtlpxAlGv
S. copri keeps pace with modern lifestyles
Subset of Segatella copri strains have acquired an additional oxygen regulator via horizontal gene transfer, which confers increased oxygen tolerance. These strains are more prevalent in industrialized countries
https://t.co/z7BtAZWt41
I'm thrilled to share our latest manuscript, published in @Nature!!
➡️ https://t.co/gtAMrHexFH...
We analyzed data from over 34,000 participants from UK and US, revealing strong associations between specific gut bacteria and markers of cardiometabolic health and dietary habits.
Exciting new #GutMicrobiome study with over 30,000 participants! @fasnicar & team link microbes to metabolic health markers & alter their abundance with diet interventions, teaming up with @timspector's ZOE app + microbiome testing.
These big datasets are what we need!
@Nature
Our Spotlight with @StrowigLab on the 2 groundbreaking studies revealing how medications could increase infection risk
@Goodman_lab@Aman_Kr25@lab_maier https://t.co/yFABXyWeGi
New paper! Combining epidemiology and experiments uncovers surprising drug-host-microbiome-pathogen interactions. Congrats @Aman_Kr25@RobynTamblyn and the rest of the team.
https://t.co/A6vr7JQx9r
Thrilled to share that my postdoc paper is finally out today in @Nature. Very thankful to my mentor Andy @Goodman_lab and all the collaborators including @RobynTamblyn.
The unfolding drama between neighboring bacteria:
@Goodman_lab ID mechanism used by human gut commensals to antagonize related bacteria. Secreted effector Bte1 alters the protein-folding machinery of targeted cells, causing substrate aggregation & toxicity
https://t.co/3ipimBav7Z
Small RNA in bacterial colonization
@MoualiYoussef @StrowigLab characterize RNA landscape of Segatella copri. ID small RNA regulator essential for colonization & whose expression is regulated by metabolism of dietary components by S. copri
https://t.co/KJp0upeqec
Bacterial small RNA makes a big impact for gut colonization
Monzel & Desai @LIH_Luxembourg highlight work of @MoualiYoussef @StrowigLab IDing SrcF, sRNA from S. copri that promotes colonization by regulating bacterial degradation of dietary carbohydrates
https://t.co/g9eGCrWuts
Segatella copri ist ein weitverbreitetes #Darmbakterium, aber noch relativ wenig erforscht. Eine Studie von @StrowigLab, @MoualiYoussef in Kooperation mit @JoergLab identifiziert jetzt eine small #RNA, die eine Schlüsselrolle bei der Besiedelung spielt.
https://t.co/hNKwjRY9Qc
Small RNA w/big roles in colonization
@MoualiYoussef @StrowigLab characterize RNA landscape of Segatella copri. ID small RNA regulator essential for colonization & whose expression is regulated by metabolism of dietary components by S. copri
https://t.co/KJp0upeY3K
RNA world of Prevotella, now Segatella, gut bacteria unfolding! Includes an sRNA essential for colonization.
Great work from the @StrowigLab. I am proud to say that three of my former students and postdocs (El Mouali, Tawk, Ponath) contributed to it.
https://t.co/MWH3f3SFTV
Check out the spectacular work led by @MoualiYoussef - giving insights into #sRNA regulation in the unexplored #Segatella/#Prevotella impacting metabolism and interactions with the host & commensals in the gut🦠
Very proud of the amazing @MoualiYoussef for this fantastic work! Finally we get some deeper mechanistic insight on the lifestyle of the mysterious Segatella/Prevotella copri in the gut.