Giulia Castellani

Researcher at IRCCS San Martino Hospital| Neuroimmunologist 🧠

[Miguel Ángel Abellanas @maabellanas]

Exciting news from my postdoc! Our latest paper is now published in @NatureComms. We discovered a critical, active brain-spleen circuit that regulates neuroprotective immunity and dictates the pace of Alzheimer’s disease progression. 👇 Let’s break down what we found.

[Ospedale San Martino Genova @SanMartino_Ge]

Il progetto sostenuto dal FIS di Giulia Castellani, ricercatrice @SanMartino_Ge, studia i meccanismi biologici che predispongono all’autismo, partendo dal legame tra le infezioni nel primo e secondo trimestre di gravidanza e la probabilità che il nascituro sviluppi la condizione.

[Giulia Castellani @castel_giulia]

📢 Happy to announce our lab at @SanMartino_Ge is supported by @mur_gov_ FIS Starting grant!
We’re studying #Neuroimmunology & #NDDs via in vivo approaches & single- cell tech! 🧠🧬
WE ARE SEEKING: ✅ Postdocs ✅ PhDs ✅ LabTech

📩 [email protected]
Please RT! 🔄

[Miguel Ángel Abellanas @maabellanas]

I’m very happy to share the preprint of one of the projects I’ve been working on during my postdoc in Michal Schwartz’s lab at the @WeizmannScience

🧠 Alzheimer’s disease disrupts bone marrow myelopoiesis, leading to systemic immune dysfunction.

https://t.co/jVj4k8rxPf

[Brain @Brain1878]

Castellani et al. show that intranasal administration of oxytocin during the neonatal period alleviates behavioural and immune alterations in a mouse model of 22q11.2 hemideletion syndrome, with the effect linked to an early reduction in BBB permeability. https://t.co/Sr6obVg3yW

[Giulia Castellani @castel_giulia]

Our study finally out in @Brain1878 ! 🧠✨

Thanks to @LabPapaleo and all co-authors for the joint effort!

Check it out 💡

🔗 https://t.co/du2nBg8gLU

[Giulia Castellani @castel_giulia]

✨

[Waggoner Lab @LabWaggoner]

Targeting CD38 immunometabolic checkpoint improves metabolic fitness and cognition in a mouse model of #Alzheimer’s disease @NatureComms @AharonJudith et al.
https://t.co/ek4N0HtadU

[Science Immunology @SciImmunology]

New research suggests that #EpsteinBarr virus infections may drive immune changes in the deep cervical lymph nodes in patients with #MultipleSclerosis, contributing to disease progression.

Learn more in Science #Immunology: https://t.co/g57zeoV4YR

[Leyre Basurco @basurco_leyre]

Happy to see our work featured on the cover of the 2025 Special Issue of @NeuroCellPress on Brain Aging! @maabellanas #MaitreyeePurnapatre @Paola632898361 and #MichalSchwartz Check out this fascinating collection of reviews & perspectives exploring the neurobiology of aging!🧠✨

[Miguel Ángel Abellanas @maabellanas]

What a beginning of 2025!! I'm glad to share a new Perspective @NatureNeuro!!🧠🧪

Monocyte-derived macrophages act as reinforcements when microglia fall short in Alzheimer’s disease.

Unroll the thread!🧶

[Rivlin Lab @LabRivlin]

Excited to share our latest study! 🧠✨ We reveal how non-direction-selective retinal ganglion cells encode motion beyond their receptive field, relaying the unconventional signals to the brain. A new insight into multimodal neurons in visual processing!
https://t.co/ho0zPM1MSG

[Giulia Castellani @castel_giulia]

@LabRivlin Congrats for this impressive work! 👏🏻

[Giulia Castellani @castel_giulia]

@FadiSheban Good luck Fadi for your next steps🍀 wish you only the best🤞🏼

[Giulia Castellani @castel_giulia]

@jonykipnis @mitchkim_mw Wow! Congrats for this beautiful study! 👏🏻

[Giulia Castellani @castel_giulia]

@mitchkim_mw @jonykipnis Congrats Mitch, Jony and the team! This study is so important!👏🏻

[Rivlin Lab @LabRivlin]

Our paper📝“Top-down modulation of the retinal code via histaminergic neurons of the hypothalamus” is now available in @ScienceAdvances! Dive in to find out how histaminergic neurons in the brain🧠modulate activity of retinal neurons in mice🐭and humans😎. https://t.co/qXvi4fPOLA

[Giulia Castellani @castel_giulia]

@IShainer @BiologyTechnion So happy for you Inbal! Good luck for this new adventure 🍀🍀

[Giulia Castellani @castel_giulia]

Our Spotlight on the groundbreaking work of @lcdsmyth, @jonykipnis, @kipnislab and colleagues is out in @TrendsImmuno. 🧠💡 Thanks to #JavierMaríaPeraltaRamos and #MichalSchwartz.

[Trends in Immunology @TrendsImmuno]

Bridging anatomical gaps between brain and immune system https://t.co/q8EIXETGvt #immunology

[Trends in Immunology @TrendsImmuno]

Bridging anatomical gaps between brain and immune system https://t.co/q8EIXETGvt #immunology

[Giulia Castellani @castel_giulia]

@lcdsmyth Writing about your article was a pleasure, Leon. Such a beautiful discovery! 🧠