cchlanger

Scientist @IMBA_Vienna interested in bringing computer science, software development, and agile project management best practices into life sciences.

[cchlanger @cchlanger]

For those bioinformaticians who drown in genomic datasets and are asked to turn them into a paper, we present HiCognition: a visual exploration and hypothesis testing tool for 3D genomics.
🪄https://t.co/eLuhCvhCml

#3DGenome #bioinfo #ComputationalBiology #genomics #BioVis

[Gerlich Lab @Gerlich_Lab]

Proud bioinformatician @cchlanger presenting our new visualisation tool @hicognition at today’s @IMPvienna / @IMBA_Vienna PhD & PostDoc day 🧬

[Elliot Hershberg @ElliotHershberg]

The tool has some cool ideas around *genomic region sets* which aim to allow "users to address biological questions about how a specific type of region is composed, regulated, and organized in 3D space."

[Ester Morreale @fmorreale_ester]

Delighted to finally share our work on BacPROTACs, published today @CellCellPress! We bring the PROTAC approach to the bacterial world, hijacking ClpCP proteolytic complexes to induce targeted protein degradation.
Read the full article here👇
https://t.co/xqnod9hvIE

[IJCAIconf @IJCAIconf]

🐦Early bird gets the worm 🪱 IJCAI-ECAI 2022 EARLY BIRD REGISTRATION closes on 30 May.
👉 Application for Student Volunteers closes on 23 May and the decision will be communicated before the early bird deadline.

https://t.co/GNWotwLZVk

#IJCAI2022 #Vienna #Austria #KI #AI

[cchlanger @cchlanger]

@IJCAIconf 🦾

[Daniel Gerlich @gerlich_daniel]

Our new preprint about @HiCognition: a visual exploration and hypothesis testing tool for 3D genomics is out: https://t.co/IK0JyzTmFA. Congratulations to @cchlanger and @michi8591 for developing this fantastic software.
#3DGenome #biology #bioinfo #genomics #DNA #chromatin

[cchlanger @cchlanger]

Discover associations using the LOLA widget 🧬HiCognition users can use a powerful widget that implements the LOLA algorithm to explore associations between genomic region sets and to discover regulatory, functional, or spatial patterns that are characteristic to them.
5/5

[cchlanger @cchlanger]

HiCognition allows data analysis of genomic datasets based on the genomic region-set approach. Combined with efficient preprocessing and interactive data visualization, this enables rapid exploration.
@hicognition
#3DGenome #bioinfo #ComputationalBiology #genomics #scicomm
1/5

[cchlanger @cchlanger]

Explore average behavior using aggregation widgets 🧬 HiCognition allows visualization of genomic features' average behavior at genomic regions, allowing users to explore both 1D- and 2D-genomic features.
4/5

[Michael Mitter @michi8591]

In contrast to conventional genome browsers, which visualize a specific subregion, HiCognition can interactively analyze large sets of genomic regions that are of particular interest in many biological questions. @hicognition
https://t.co/dwjXoqrHHS
#3DGenome #bioinfo #DNA