The @AlexsLemonade#MillionMile is on! All donations made TODAY 9/11 and TOMORROW 9/12 are DOUBLED by the amazing @VolvoCarUSA. To join us on this mission to achieve a world without pediatric cancer, please click donate on our lab’s fundraising page: https://t.co/wq6O5ZnQFG
Check out our (@SchmidtLabHMS) new preprint, a collaboration with @lingwoodlab and @BalazsLab at @ragoninstitute! We investigate a possible approach to elicit neutralizing antibodies against future emerging coronaviruses as well as SARS-CoV-2
https://t.co/GVXz3DUKCs
Congratulations to Dr. Cathcart and the whole team! The binding interface between E1 and the a1 helix of E2 comprises an exciting new target site for blocking E1/E2 ubiquitin transfer. Ultimately, molecules that engage this site could promise a new means of proteasomal blockade.
https://t.co/aS6cGf067u
Excited to share Zack's, Cat's, and my latest paper in which we biochemically and structurally characterize a homogeneous BAX oligomer and use it to interrogate the BAX activation pathway. Special thanks to @LorenWalensky and @jrengen for their mentorship!
I'm excited to share our latest work, led by Zack Hauseman and I, in which we conduct a disulfide tethering screen to identify fragments that covalently modify BFL-1 Cysteine 55 and thereby inhibit BFL-1 blockade of mitochondrial apoptosis!
https://t.co/m4EzQccCFW
https://t.co/eVyuPQWJ6Q
Check out the Walensky Lab's latest paper led by Dr. Yael Ben-Nun, in which we develop and structurally characterize HDMX selective SAH-p53 peptides.
Excited to share our work on the RND transporter AcrB! Thank you to Ben Luisi @CamBiochem and everyone in the Luisi lab for all your support and mentorship.
Multidrug efflux in bacteria contributes to antibiotic resistance during host infection. Here, Du et al. and Ben Luisi @CamBiochem determine the structure of a multi-drug transporter by #cryoEM under conditions that mimic the natural membrane environment. https://t.co/ervd2TUtYG