Carlos F. Lagos

Pharmaceutical Chemist, Molecular Craftsman, PhD

[Agencia Nacional de Investigación y Desarrollo @ANID_Chile]

Desde Valdivia, investigadores e investigadoras descubrieron un mecanismo clave en las neuronas. El estudio, financiado principalmente por @anid_chile; vía Fondecyt, y publicado en Cell Metabolism; ayuda a entender cómo las neuronas se protegen del estrés oxidativo, un tipo de daño celular vinculado a enfermedades como el Alzheimer, el Parkinson y los accidentes cerebrovasculares.

Este hallazgo abre nuevas líneas de investigación para comprender qué ocurre cuando estos mecanismos de protección fallan. 🔬

[Matt Dancho (Business Science) @mdancho84]

🚨 BREAKING: IBM launches a free Python library that converts ANY document to data

Introducing Docling. Here's what you need to know: 🧵

[Agencia Nacional de Investigación y Desarrollo @ANID_Chile]

📢 ¡Ya está disponible el Calendario de Convocatorias 2026 de ANID! Conoce y planifica la postulación a oportunidades de financiamiento para proyectos individuales y asociativos en investigación, tecnología, innovación y estudios de postgrado. Revisa las fechas clave en: https://t.co/k2Tm0ZsLDY

[Boris Cherny @bcherny]

I'm Boris and I created Claude Code. I wanted to quickly share a few tips for using Claude Code, sourced directly from the Claude Code team. The way the team uses Claude is different than how I use it. Remember: there is no one right way to use Claude Code -- everyones' setup is different. You should experiment to see what works for you!

[Mushtaq Bilal, PhD @MushtaqBilalPhD]

Libgen, Sci-Hub, and Z-library had millions of pirated academic books and papers.

So, they were shut down. We shouldn't use them anyway.

We should help billion-dollar academic publishers get richer.

Anyway, here's how to access these libraries:

Don't do this!

[Carlos F. Lagos @cflagospharma]

https://t.co/VNWgzOjcZS

[Patrick Walters @wpwalters]

New Practical Cheminformatics Post, "Useful RDKit Utils - A Mötley Collection of Helpful Routines"
https://t.co/MaP7vjkQ39

[BryanRoth @zenbrainest]

Wow, wow, wow!!!
The structure of human sweetness https://t.co/Cok9PiQJ3M

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in siRNA therapies, here's a review https://t.co/BBH5NPXYDz
https://t.co/9DGL8S2jLN

[BryanRoth @zenbrainest]

Yuuge paper on #psychedelics The structural diversity of psychedelic drug actions revealed https://t.co/7buwS3kttF

[CarlssonLab @CarlssonLab]

Identifying ligands for therapeutic targets among billions of compounds is challenging! Can we search ultra-large chemical libraries more efficiently?
Yes! Read about our docking/ML approach:
https://t.co/K2dsOzDzGZ

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in RNA-based medicines such as antisense oligonucleotides and siRNAs, here's a review discussing strategies to address challenges associated with their applicability, efficacy and safety profiles
https://t.co/VTYFyPbfoM
https://t.co/G0YbDtsMST

[FeRNAndo Valiente 🧬🧫🔬 @pelaofunk]

Solo falta el 10%....muy muy cerca de la meta!!!
Aun puedes ADQUIRIR TU ENTRADA PARA MAÑANA O HACER TU DONACIÓN

https://t.co/LPPDyHpXvG

🗓️ *Sábado 1 de marzo*
⏰ *Entre 12 y 20 horas*
📍 *Villa Rovereto, Laguna de Aculeo, Paine*

Te esperamos!

[Gabriela Repetto 🧬 @gmrepetto]

El último día de febrero se conmemora el día mundial de las #EnfermedadesRaras #PocoFrecuentes @rarediseaseday . En preparación para este día, compartiremos durante esta semana los resultados principales de nuestro trabajo de investigación colaborativa en el @ICIM_UDD et al.

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in personalized therapeutics such as antisense oligonucleotides for ultra-rare diseases, this review from @irdirc discusses progress in the field and provides a roadmap for their development
https://t.co/HtwRVgHPZr
https://t.co/E8tvMfMihh

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in cancer immunotherapy, this Review in our February issue discusses opportunties and challenges in using vaccines for cancer prevention
https://t.co/1P35fYAMRv
https://t.co/Jco1WHpn7L

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in therapeutic strategies for Duchenne muscular dystrophy, here's a review
https://t.co/Dwrf5nBjQ1
https://t.co/wRGtBlbm5u

[Nature Reviews Drug Discovery @NatRevDrugDisc]

For readers interested in new epilepsy therapies in development, here's a comprehensive recent review
https://t.co/AIGSjsvfHh
https://t.co/GPFEt6A22i

[Mushtaq Bilal, PhD @MushtaqBilalPhD]

Google just introduced an AI co-scientist.

"To help uncover new, original knowledge and to formulate...novel research hypotheses...building upon prior evidence and aligned to scientist-provided research objectives and guidance."

If it's half as good, it'll be revolutionary.

[Investigación USS @VRID_USS]

🎓Nos enorgullece felicitar a nuestros y nuestras estudiantes de doctorado @USanSebastian por haber logrado la adjudicación de una beca altamente competitiva en la Convocatoria 2025 de Becas de Doctorado Nacional y primer llamado de Beneficios Complementarios de este año