Prashen Chelikani

Professor, UManitoba. Taste biology, GPCRs, Host-microbes.

[Craig Baird - Canadian History Ehx @CraigBaird]

On this day in 1958, Terry Fox was born in Winnipeg.
A Canadian hero, over $1 billion has been raised in his name since he embarked on The Marathon of Hope in 1980.

📸 Gail Harvey

Learn more in my Deep Dive 👇
https://t.co/yKMS2sh8Oy

[Yongqiang Chen, Ph.D. @YongqiangChen1]

We just published. 39 candidate autophagy cargoes are degraded simultaneously by autophagy. Autophagy can differentially regulate protein expression across 4 cell death pathways.

Bitter taste receptor T2R14 and autophagy inhibition influence program... https://t.co/87GT0j4wFP

[Sai P Pydi @saip_pydi]

Thrilled to share our new paper in @MolMetab ! 🎉
In this study we asked “what really happens inside the pancreas as obesity progresses?”
Temporal single-cell transcriptional dynamics of murine pancreatic isl... https://t.co/8051JlWjf5

[Arun K. Shukla @arshukla]

Delighted to share this amazing collaborative study involving our laboratory @IITKanpur now published in @Nature! This was spearheaded by David Baker's lab @UWproteindesign with contributions from several labs across the globe!
Link: https://t.co/0AMRqW4eCx

[Arun K. Shukla @arshukla]

Structural energetics of cold sensitivity | Nature

https://t.co/hg5biyecv9

[Saeid Ghavami @CellAutophagy]

Hierarchical Machine Learning Uncovers Topological Signatures of Autophagy Regulation by Oral Bacteria in OSCChttps://www.biorxiv.org/content/10.64898/2025.12.29.696881v1
#MachineLearning #Autophagy

[Saeid Ghavami @CellAutophagy]

Using hierarchical, label-free ML + network analysis, we identify non-random biological signatures and introduce a Dysbiosis Index that separates pro-cancer vs protective bacterial states—validated across independent clinical datasets.
@um_research @CancerCareMB

[Saeid Ghavami @CellAutophagy]

Key insight: Autophagy is not binary.
Pathogenic oral bacteria hijack autophagy to drive inflammation, EMT, and tumor aggressiveness, while commensals stabilize homeostatic autophagy and epithelial integrity. The difference is encoded in network topology.
#OralCancer #Microbiome

[Research Manitoba @Research_MB]

2025 Innovation Proof-of-Concept recipients are advancing transformative ideas, from sustainable battery materials and smart food-quality tools to 3D-printed housing solutions and next-generation diagnostics, as they move their projects closer to real-world impact and commercial success. Learn more about how the IPoC grant affects their professional lives at: https://t.co/kQACiFYLWq

[Science News @SciencNews]

Handwritten notes are more useful for studying and committing to memory than typed notes, ultimately contributing to higher achievement for college students.

https://t.co/pYuE7QpTzm

[Pingzhao Hu @PingzhaoH]

Thrilled to announce our work "Integrative analysis of taste genetics and the dental plaque microbiome in early childhood caries" is now out in Cell Reports https://t.co/wkVA8I4Cza @CIHR_ICR, @WesternU, @SchulichMedDent, @westernuBiochem, @um_bmg , @Chelikanilab, @wasifmohdkhan

[Sai P Pydi @saip_pydi]

Thank you @India_Alliance for highlighting our work!! I truly couldn’t have set up the lab without the funding from IA- @DBTIndia @wellcometrust!! Thank you @IITKanpur @mfcem_iitk @BSBEIITK1 for the support!!

[Sai P Pydi @saip_pydi]

Finally!!! The structure of human sweetness: Cell https://t.co/VWc4AwfWoC

[Peter Cattini @aloss4wrds]

Thanks to all that came to celebrate the Cattini Lab Reunion and mark Yan’s retirement. Hope your stories are going well!

[Paul Marcogliese @PCMarcogliese]

Over 1300 Canadian researchers and climbing.
@StanKutcher

https://t.co/ZLXE7hK2bA

[The Nobel Prize @NobelPrize]

Did you know that our body 'eats' itself to stay healthy?

Yoshinori Ohsumi was awarded the 2016 Nobel Prize in Physiology or Medicine for discovering the mechanisms for ‘self-eating’ or autophagy, which refers to the way our cells destroy and recycle their own contents.

[Science Magazine @ScienceMagazine]

A genetic detective tackles a touchy question: How often are children genetically unrelated to their presumed fathers?

Learn more: https://t.co/FF6btPfYqq @NewsfromScience

[The Nobel Prize @NobelPrize]

"If you're working non-stop all the time you will burn out."

How do you keep a healthy work-life balance as a scientist? Hear 2009 chemistry laureate Venki Ramakrishnan share his best advice on how to achieve a good work-life balance.

#NobelPrize

[bioRxiv Genomics @biorxiv_genomic]

Integrative analysis of taste genetics and the dental plaque microbiome in early childhood caries https://t.co/xNHNqDnXmz #biorxiv_genomic

[Arun K. Shukla @arshukla]

GPCR drug discovery: new agents, targets and indications | Nature Reviews Drug Discovery
https://t.co/GI5Mz64CD0